Patents by Inventor Petra Rach

Petra Rach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5665716
    Abstract: New 24-homo vitamin D derivatives of formula I ##STR1## are described, in which R.sup.1 means a hydrogen atom, a hydroxy, an alkanoyloxy group with 1 to 8 carbon atoms or an aralkanoyloxy group with up to 8 carbon atoms,R.sup.2 and R.sup.3, independently of one another, mean a linear or branched alkyl group with 1 to 4 carbon atoms, a trifluoromethyl group or together mean a saturated carbocyclic ring with 3 to 9 carbon atoms formed with carbon atom 25,R.sup.4 and R.sup.5, independently of one another, mean a hydrogen atom, an alkanoyl group with 1 to 8 carbon atoms or an aralkanoyl group with up to 8 carbon atoms, andA and B each mean a hydrogen or together a second bond, andn stands for 1, 2, 3,4 or 5.
    Type: Grant
    Filed: October 2, 1990
    Date of Patent: September 9, 1997
    Assignee: Schering Aktiengesellschaft
    Inventors: Gerald Kirsch, Gunter Neef, Katicia Schwarz, Matthias Brautigam, Ruth Thieroff-Ekerdt, Petra Rach
  • Patent number: 5532228
    Abstract: The invention discloses side-chain homologous vitamin D derivatives of formula I ##STR1## in which R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6, B, and D have the meanings defined in the specification and either (1) A is a direct bond between carbon atoms 20 and 22 and X is an oxy alkylene radical, --(CH.sub.2).sub.n O-- where n is 1 to 3; (2) A is a methylene bridge, --CH.sub.2 --, between carbon atoms 20 and 22 and X is either an alkylene radical, --(CH.sub.2).sub.n -- or an oxy alkylene radical, --(CH.sub.2).sub.n O--, where n is 1 to 3; or (3) if A is a direct bond and B and D together form a second bond, then X(R.sup.5) (R.sup.6) is ##STR2## The compounds possess proliferation-inhibiting and cell-differentiating activity.
    Type: Grant
    Filed: June 1, 1993
    Date of Patent: July 2, 1996
    Assignee: Schering Aktiengesellschaft
    Inventors: Gunter Neef, Gerald Kirsch, Andreas Stein-Eyer, Katica Schwarz, Matthias Brautigam, Ruth Thieroff-Ekerdt, Petra Rach
  • Patent number: 5411949
    Abstract: 23-Oxa-derivatives in the vitamin D series of formula I ##STR1## are described in which R.sup.1, R.sup.2 and R.sup.4 independently of one another mean a hydrogen atom or an acyl group with 1 to 9 carbon atoms,R.sup.3 each means a hydrogen atom or each a linear or branched alkyl group with 1 to 4 carbon atoms and X means an alkylene radical--(CH.sub.2).sub.n -- with n=1, 2, 3, and if n=1, R.sup.3 each cannot be a methyl or propyl group, as well as a process for their production.The compounds have proliferation-inhibiting and cell-differentiation effects and are suitable for the production of pharmaceutical agents.
    Type: Grant
    Filed: July 19, 1993
    Date of Patent: May 2, 1995
    Assignee: Schering Aktiengesellschaft
    Inventors: Gunter Neef, Andreas Steinmeyer, Gerald Kirsch, Katica Schwarz, Martin Haberey, Ruth Thieroff-Ekerdt, Petra Rach
  • Patent number: 5292728
    Abstract: New 24-oxa derivatives in the vitamin D series of general formula I are described in whichR.sup.1, R.sup.2 and R.sup.5, independently of one another, mean a hydrogen atom or an acyl group with 1 to 9 carbon atoms,R.sup.3 means a hydrogen atom or a linear or branched alkyl group with 1 to 4 carbon atoms andR.sup.4 means a hydrogen atom each or a linear or branched alkyl group each with 1 to 4 carbon atoms.Pharmaceutical preparations which contain these compounds are also disclosed.
    Type: Grant
    Filed: December 4, 1992
    Date of Patent: March 8, 1994
    Assignee: Schering Aktiengesellschaft
    Inventors: Gunter Neef, Gerald Kirsch, Andreas Steinmeyer, Katica Schwarz, Matthias Brautigam, R. Thieroff-Ekerdt, Petra Rach
  • Patent number: 5089175
    Abstract: Hydroxyalkane carboxylic acid derivatives of general formula I ##STR1## in which n means the numbers 7 to 18,R.sub.1 represents a hydrogen atom or an acyl group with a maximum of 16 carbon atoms, andoptionally an alkylene group with 4 to 8 carbon atoms interrupted by an oxygen atom or a nitrogen atom, are useful for the production of pharmaceutical agents for local treatment of diseases of the skin and mucous membranes.
    Type: Grant
    Filed: February 16, 1990
    Date of Patent: February 18, 1992
    Assignee: Schering Aktiengesellschaft
    Inventors: Christopher G. Earnshaw, Gerald Kirsch, Petra Rach, Ruth Thieroff-Ekerdt, Michael Topert
  • Patent number: 5010071
    Abstract: Androstane derivatives of the general Formula I ##STR1## in which R.sub.1 represents a hydrogen atom or a methyl group,X and Y each mean hydrogen atoms or together a carbon-carbon bond, andR.sub.2 symbolizes a hydrogen atom or an alkyl group with 1 to 6 carbon atoms,are pharmaceutically effective substances which have a distinct antiandrogenic effectiveness in topical application.
    Type: Grant
    Filed: July 13, 1989
    Date of Patent: April 23, 1991
    Assignee: Schering Aktiengesellschaft
    Inventors: Dieter Bittler, Henry Laurent, Petra Rach, Michael Topert
  • Patent number: 4859659
    Abstract: Dermatics are claimed which are characterized in that they contain as the active compound one or two 17.beta.-methyl-18-nor steroids of general Formula I ##STR1## wherein is a single bond or a double bond,R.sub.1 is a hydrogen atom or a methyl group, andR.sub.2 is an alkyl group of maximally 6 carbon atoms, optionally substituted by an alkanoyloxy group containing 2-6 carbon atoms.
    Type: Grant
    Filed: December 17, 1986
    Date of Patent: August 22, 1989
    Assignee: Schering Aktiengesellschaft
    Inventors: Dieter Bittler, Henry Laurent, Klaus Nickisch, Petra Rach