Patents by Inventor Phil Gunning

Phil Gunning has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MELANOMA BIOMARKERS
    Publication number: 20220317125
    Abstract: The present invention relates to autoantibody biomarkers associated with melanoma. The autoantibody biomarkers can be used to detect or diagnose melanoma and can also be used to inform treatment of melanoma patients, particularly treatment with checkpoint inhibitors. The autoantibody biomarkers can be used in a variety of methods including: methods of selecting melanoma patients for treatment; methods of predicting responsiveness to treatment; methods of predicting survival responsive to treatment; and methods of predicting the risk of immune-related adverse events (irAEs) in patients treated with checkpoint inhibitors.
    Type: Application
    Filed: June 19, 2020
    Publication date: October 6, 2022
    Inventors: Phil GUNNING, Petra BUDDE, Hans-Dieter ZUCHT, Manuel BRÄUTIGAM
  • THERAPEUTIC METHODS AND USES OF SAPOGENINS AND THEIR DERIVATIVES
    Publication number: 20110190249
    Abstract: The invention discloses therapeutic methods and uses of certain steroidal sapogenins, related compounds and derivatives thereof, in the treatment of non-cognitive neurodegeneration, non-cognitive neuromuscular degeneration, motor-sensory neurodegeneration or receptor dysfunction or loss in the absence of cognitive, neural and neuromuscular impairment.
    Type: Application
    Filed: April 12, 2011
    Publication date: August 4, 2011
    Applicant: PHYTOPHARM PLC
    Inventors: Daryl REES, Phil Gunning, Antonia Orsi, Zongqin Xia, Yaer Hu
  • SUBSTITUTED SAPOGENINS AND THEIR USE
    Publication number: 20100087411
    Abstract: The invention discloses substituted sapogenins and their use in the treatment of cognitive disfunction and similar conditions.
    Type: Application
    Filed: August 11, 2009
    Publication date: April 8, 2010
    Applicant: Phytopharm PLC
    Inventors: Paul Barraclough, Jim Hanson, Phil Gunning, Daryl Rees, Zongqin Xia, Yaer Hu
  • 5-Beta-sapogenin and pseudosapogenin derivatives and their use in the treatment of dementia
    Patent number: 7507720
    Abstract: The invention discloses the use of sapogenin derivatives in the treatment of cognitive disfunction and similar conditions. Methods of treatment and pharmaceutical compositions are also disclosed.
    Type: Grant
    Filed: August 11, 2006
    Date of Patent: March 24, 2009
    Assignee: Phytopharm PLC
    Inventors: Paul Barraclough, Jim Hanson, Phil Gunning, Daryl Rees, Zongqin Xia, Yaer Hu
  • Substituted sapogenins and their use
    Publication number: 20080207576
    Abstract: The invention discloses substituted sapogenins and their use in the treatment of cognitive disfunction and similar conditions.
    Type: Application
    Filed: August 23, 2007
    Publication date: August 28, 2008
    Inventors: Paul Barraclough, Jim Hanson, Phil Gunning, Daryl Rees, Zongqin Xia, Yaer Hu
  • 5-Hydroxysapogenin derivatives with anti-dementia activity
    Publication number: 20080020021
    Abstract: The invention discloses the use of 5-hydroxysapogenin derivatives in the treatment of cognitive disfunction and similar conditions. Methods of treatment and pharmaceutical composition are also disclosed.
    Type: Application
    Filed: August 20, 2007
    Publication date: January 24, 2008
    Applicant: PHYTOPHARM PLC
    Inventors: Paul Barraclough, Jim Hanson, Phil Gunning, Daryl Rees, Zongqin Xia, Yaer Hu
  • Sapogenin derivatives and their use in the treatment of cognitive dysfunction
    Publication number: 20080021004
    Abstract: The invention discloses the use of sapogenin derivatives in the treatment of cognitive dysfunction and similar conditions. Methods of treatment and pharmaceutical composition are also disclosed.
    Type: Application
    Filed: August 20, 2007
    Publication date: January 24, 2008
    Applicant: PHYTOPHARM PLC
    Inventors: Paul Barraclough, Jim Hanson, Phil Gunning, Daryl Rees, Zongqin Xia, Yaer Hu
  • 5-Beta-sapogenin and pseudosapogenin derivatives and their use in the treatment of dementia
    Publication number: 20060276415
    Abstract: The invention discloses the use of sapogenin derivatives in the treatment of cognitive disfunction and similar conditions.
    Type: Application
    Filed: August 11, 2006
    Publication date: December 7, 2006
    Applicant: PHYTOPHARM PLC
    Inventors: Paul Barraclough, Jim Hanson, Phil Gunning, Daryl Rees, Zongqin Xia, Yaer Hu
  • 5-?-sapogenin and pseudosapogenin derivatives and their use in the treatment of dementia
    Patent number: 7138427
    Abstract: The invention discloses the use of sapogenin derivatives in the treatment of cognitive disfunction and similar conditions.
    Type: Grant
    Filed: March 28, 2002
    Date of Patent: November 21, 2006
    Assignee: Phytopharm PLC.
    Inventors: Paul Barraclough, Jim Hanson, Phil Gunning, Daryl Rees, Zongqin Xia, Yaer Hu
  • Steroidal sapogenins and their derivatives for treating Alzheimer's disease
    Publication number: 20060182817
    Abstract: The invention discloses the use of a number of saponins and sapogenins, notably those of steroidal structure, in the treatment of cognitive disfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.
    Type: Application
    Filed: July 17, 2004
    Publication date: August 17, 2006
    Inventors: Zongqin Xia, Yaer Hu, Ian Rubin, Jonathan Brostoff, Brian Whittle, Weijun Wang, Phil Gunning
  • 5-hydroxysapogenin derivatives with anti-dementia activity
    Publication number: 20060165757
    Abstract: The invention discloses the use of 5-hydroxysapogenin derivatives in the treatment of cognitive disfunction and similar conditions. Methods of treatment and pharmaceutical composition are also disclosed.
    Type: Application
    Filed: February 2, 2006
    Publication date: July 27, 2006
    Applicant: Phytopharm PLC
    Inventors: Paul Barraclough, Jim Hanson, Phil Gunning, Daryl Rees, Zongqin Xia, Yaer Hu
  • 5-beta-sapogenin and pseudosapogenin derivatives and their use in the treatment of dementia
    Publication number: 20060100184
    Abstract: The invention discloses the use of sapogenin derivatives in the treatment of cognitive disfunction and similar conditions.
    Type: Application
    Filed: March 28, 2002
    Publication date: May 11, 2006
    Inventors: Paul Barraclough, Jim Hanson, Phil Gunning, Daryl Rees, Zongqin Xia, Yaer Hu
  • Therapeutic methods and uses of sapogenins and their derivatives
    Publication number: 20050130948
    Abstract: The invention discloses therapeutic methods and uses of certain steroidal sapogenins, related compounds and derivatives thereof, in the treatment of non-cognitive neurodegeneration, non-cognitive neuromuscular degeneration, motor-sensory neurodegeneration or receptor dysfunction or loss in the absence of cognitive, neural and neuromuscular impairment.
    Type: Application
    Filed: March 27, 2003
    Publication date: June 16, 2005
    Inventors: Daryl Rees, Phil Gunning, Antonia Orsi, Zongqin Xia, Yaer Hu
  • Steroidal sapogenins and their derivatives for treating alzheimer's disease
    Patent number: 6812213
    Abstract: The invention discloses the use of a number of saponins and sapogenins, notably those of steroidal structure, in the treatment of cognitive disfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.
    Type: Grant
    Filed: February 15, 2002
    Date of Patent: November 2, 2004
    Assignee: Phytopharm, plc
    Inventors: Zongqin Xia, Yaer Hu, Ian Rubin, Jonathan Brostoff, Brian Whittle, Weijun Wang, Phil Gunning
  • Sapogenin derivatives, their synthesis and use, and methods based upon their use
    Publication number: 20040147495
    Abstract: The invention discloses certain steroidal sapogenins and derivatives thereof, and their use in the treatment of cognitive dysfunction, non-cognitive neurodegeneration, non-cognitive neuromuscular degeneration, and receptor loss in the absence of cognitive, neural and neuromuscular impairment. Methods of synthesis, treatment and pharmaceutical compositions are also disclosed.
    Type: Application
    Filed: March 4, 2004
    Publication date: July 29, 2004
    Inventors: Paul Barraclough, Jim Hanson, Phil Gunning, Daryl Rees, Zongqin Xia, Yaer Hu
  • Substituted sapogenins and their use
    Publication number: 20030158161
    Abstract: The invention discloses substituted sapogenins and their use in the treatment of cognitive disfunction and similar conditions.
    Type: Application
    Filed: July 3, 2002
    Publication date: August 21, 2003
    Applicant: PHYTOPHARM PLC.
    Inventors: Paul Barraclough, Jim Hanson, Phil Gunning, Daryl Rees, Zongqin Xia, Yaer Hu
  • Smilagenin and anzurogenin-D for the treatment of alzheimer's disease
    Publication number: 20030118673
    Abstract: The invention discloses the use of smilagenin and anzurogenin D in the treatment of cognitive dysfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.
    Type: Application
    Filed: January 3, 2003
    Publication date: June 26, 2003
    Inventors: Zongqin Xia, Yaer Hu, Ian Rubin, Jonathan Brostoff, Brian Whittle, Weijun Wang, Phil Gunning
  • 5-hydroxysapogenin derivatives with anti-dementia activity
    Publication number: 20030100542
    Abstract: The invention discloses the use of 5-hydroxysapogenin derivatives in the treatment of cognitive disfunction and similar conditions. Methods of treatment and pharmaceutical composition are also disclosed.
    Type: Application
    Filed: March 28, 2002
    Publication date: May 29, 2003
    Inventors: Paul Barraclough, Jim Hanson, Phil Gunning, Daryl Rees, Zongqin Xia, Yaer Hu
  • 5-beta-sapogenin and pseudosapogenin derivatives and their use in the treatment of dementia
    Publication number: 20030004147
    Abstract: The invention discloses the use of sapogenin derivatives in the treatment of cognitive disfunction and similar conditions.
    Type: Application
    Filed: March 28, 2002
    Publication date: January 2, 2003
    Inventors: Paul Barraclough, Jim Hanson, Phil Gunning, Daryl Rees, Zongqin Xia, Yaer Hu
  • Steroidal sapogenins and their derivatives for treating alzheimer's disease
    Publication number: 20020193317
    Abstract: The invention discloses the use of a number of saponins and sapogenins, notably those of steroidal structure, in the treatment of cognitive disfunction and similar conditions. Methods of treatment, and pharmaceutical compositions are also disclosed.
    Type: Application
    Filed: February 15, 2002
    Publication date: December 19, 2002
    Inventors: Zongqin Xia, Yaer Hu, Ian Rubin, Jonathan Brostoff, Brian Whittle, Weijun Wang, Phil Gunning