Abstract: Described herein are compounds that may selectively bind to Hsp90, methods of using the compounds, and kits including the compounds. The compounds may allow for selective detection of Hsp90 in a sample.

Abstract: Described herein are compounds that may selectively bind to Hsp90, methods of using the compounds, and kits including the compounds. The compounds may allow for selective detection of Hsp90 in a sample.

Abstract: Substituted indazoles linked to a substituted adenine with a polyethylene glycol moiety selectively bind to Hsp90. The compounds include detection moieties such as fluorophores and are useful in methods and kits for selective detection of Hsp90 in a sample.

Abstract: Described herein are compounds that may selectively bind to Hsp90, methods of using the compounds, and kits including the compounds. The compounds may allow for selective detection of Hsp90 in a sample.

Abstract: Described herein are compounds that may selectively bind to Hsp90, methods of using the compounds, and kits including the compounds. The compounds may include detection moieties such as fluorophores that may allow for selective detection of Hsp90 in a sample.

Abstract: Described herein are substituted indazoles comprising formula (II) that may selectively bind to Hsp90, methods of using the compounds, and kits including the compounds. Formula (II) may link to detection moieties such as fluorophores that may allow for selective detection of Hsp90 in a sample.

Abstract: Described herein are compounds that may selectively bind to Hsp90, methods of using the compounds, and kits including the compounds. The compounds may include detection moieties such as fluorophores that may allow for selective detection of Hsp90 in a sample.

Abstract: Described herein are 6-aminopurine compounds comprising formula (III) that may selectively bind to Hsp90, methods of using the compounds, and kits including the compounds. Formula (III) may link to detection moieties such as fluorophores that may allow for selective detection of Hsp90 in a sample.

Abstract: Described herein are compounds that may selectively bind to Hsp90, methods of using the compounds, and kits including the compounds. The compounds may include detection moieties such as fluorophores that may allow for selective detection of Hsp90 in a sample.

Abstract: A track system, for use in connection with bundling one or more objects positioned within a bundling station, includes guiding a length of wire through a track guide assembly. The track guide assembly includes a plurality of straight and corner track segments coupled to each other and to a carrier plate subassembly, the track guide assembly substantially enclosing a wire guide path to guide the length of wire about the one or more objects. The track system further includes a pneumatic system configured to reduce a pressure to release the plurality of straight and corner track segments to free the length of wire during a tension cycle and to increase the pressure to fix the plurality of straight and corner track segments during a feed cycle. Related systems and methods are also provided.

Abstract: The present description discusses apparatuses and methods for applying straps around a bundle of objects by applying a variable force to tension the strap around the bundle of objects and then actuating a series of cams to control the sealing of the strap around the bundle of objects. The apparatus includes a track assembly extending substantially about a strapping station. The track assembly is adapted to receive a strap and to release the strap during a tensioning operation. An accumulator delivers strap to the track assembly. The accumulator has a strap conveyor system that defines a strap path and an accumulator container adjacent to the strap path. Strap can be accumulated in the accumulator container and subsequently delivered to the track assembly.

Abstract: Described herein are substituted indazoles that may selectively bind to Hsp90, methods of using the compounds, and kits including the compounds. The compounds may include detection moieties such as fluorophores that may allow for selective detection of Hsp90 in a sample.

Abstract: A twister assembly for use in connection with bundling one or more objects with a length of wire may cut, grip, eject, and twist the length of wire. The twister assembly includes a main shaft driven by a main shaft motor and a twister shaft driven by a twister motor. The main shaft may be operatively coupled to a gripping mechanism, which is operable between an open and a closed position, a cutting mechanism, and an ejector mechanism. The twister shaft may be operatively coupled to a twisting mechanism, where the twisting mechanism includes a plurality of gears configured to rotate a twister pinion. The twister pinion is further configured to engage the length of wire and twist a portion of the length of wire to form a knot. Related twister assemblies and methods are also provided.

Abstract: Described herein are compounds that may selectively bind to Hsp90, methods of using the compounds, and kits including the compounds. The compounds may include detection moieties such as fluorophores that may allow for selective detection of Hsp90 in a sample.

Abstract: The present description discusses apparatuses and methods for applying straps around a bundle of objects by applying a variable force to tension the strap around the bundle of objects and then actuating a series of cams to control the sealing of the strap around the bundle of objects. The apparatus includes a track assembly extending substantially about a strapping station. The track assembly is adapted to receive a strap and to release the strap during a tensioning operation. An accumulator delivers strap to the track assembly. The accumulator has a strap conveyor system that defines a strap path and an accumulator container adjacent to the strap path. Strap can be accumulated in the accumulator container and subsequently delivered to the track assembly.

Abstract: A twister assembly for use in connection with bundling one or more objects with a length of wire may cut, grip, eject, and twist the length of wire. The twister assembly includes a main shaft driven by a main shaft motor and a twister shaft driven by a twister motor. The main shaft may be operatively coupled to a gripping mechanism, which is operable between an open and a closed position, a cutting mechanism, and an ejector mechanism. The twister shaft may be operatively coupled to a twisting mechanism, where the twisting mechanism includes a plurality of gears configured to rotate a twister pinion. The twister pinion is further configured to engage the length of wire and twist a portion of the length of wire to form a knot. Related twister assemblies and methods are also provided.

Abstract: A track system, for use in connection with bundling one or more objects positioned within a bundling station, includes guiding a length of wire through a track guide assembly. The track guide assembly includes a plurality of straight and corner track segments coupled to each other and to a carrier plate subassembly, the track guide assembly substantially enclosing a wire guide path to guide the length of wire about the one or more objects. The track system further includes a pneumatic system configured to reduce a pressure to release the plurality of straight and corner track segments to free the length of wire during a tension cycle and to increase the pressure to fix the plurality of straight and corner track segments during a feed cycle. Related systems and methods are also provided.

Abstract: The present description discusses apparatuses and methods for applying straps around a bundle of objects by applying a variable force to tension the strap around the bundle of objects and then actuating a series of cams to control the sealing of the strap around the bundle of objects. The apparatus includes a track assembly extending substantially about a strapping station. The track assembly is adapted to receive a strap and to release the strap during a tensioning operation. An accumulator delivers strap to the track assembly. The accumulator has a strap conveyor system that defines a strap path and an accumulator container adjacent to the strap path. Strap can be accumulated in the accumulator container and subsequently delivered to the track assembly.

Abstract: The efficiency of an etching process may be increased in various ways, and the cost of an etching process may be decreased. Unused etchant may be isolated and recirculated during the etching process. Etching byproducts may be collected and removed from the etching system during the etching process. Components of the etchant may be isolated and used to general additional etchant. Either or both of the etchant or the layers being etched may also be optimized for a particular etching process.

Abstract: This disclosure provides systems, methods and apparatus, including computer programs encoded on computer storage media, for detecting proximity and/or color of an object. In one aspect, an optical sensor includes a plurality of transmissive interferometric elements, a plurality of detectors positioned to detect the presence and/or intensity of light transmitted through the elements, and a processor to determine the proximity of an object based at least in part upon input from the detectors. An optical signal can be sensed by selectively actuating certain elements in a set of transmissive interferometric elements in an array to allow transmission of optical signals within a first spectrum through the array, and detecting optical signals transmitted through the array.