Patents by Inventor Philip J. O'Connell

Philip J. O'Connell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11674181
    Abstract: A method for identifying a renal allograft recipient at risk for chronic allograft damage or interstitial fibrosis and tubular atrophy (IF/TA) by comparing the transcription level of a preselected gene signature set with the transcription level of a comparison standard, and diagnosing the recipient as being at risk for chronic allograft damage if the transcription level of the preselected gene signature set is significantly higher than the transcription level of the comparison standard.
    Type: Grant
    Filed: February 1, 2021
    Date of Patent: June 13, 2023
    Assignees: Icahn School of Medicine at Mount Sinai, Western Sydney Local Health District
    Inventors: Barbara Murphy, Weijia Zhang, Philip J. O'Connell
  • Publication number: 20210230700
    Abstract: A method for identifying a renal allograft recipient at risk for chronic allograft damage or interstutial fibrosis and tubular atrophy (IF/TA) by comparing the transcription level of a preselected gene signature set with the transcription level of a comparison standard, and diagnosing the recipient as being at risk for chronic allograft damage if the transcription level of the preselected gene signature set is significantly higher than the transcription level of the comparison standard.
    Type: Application
    Filed: February 1, 2021
    Publication date: July 29, 2021
    Inventors: Barbara Murphy, Weijia Zhang, Philip J. O`Connell
  • Patent number: 10725026
    Abstract: A method for identifying a kidney transplant recipient at an increased risk of developing interstitial fibrosis or tubular atrophy which comprises obtaining a post-transplant urine sample from the kidney transplant recipient; measuring the level of clusterin in the urine sample; comparing the level of clusterin in the patient sample to the level of clusterin in a control sample from the urine of a non-fibrotic kidney transplant recipient; diagnosing a kidney transplant recipient with a clusterin level that is significantly higher than the clusterin level in the control as being at an increased risk of developing interstitial fibrosis or tubular atrophy.
    Type: Grant
    Filed: November 13, 2017
    Date of Patent: July 28, 2020
    Assignees: Icahn School of Medicine at Mount Sinai, Westmead Institute For Medical Research, Western Sydney Local Health District
    Inventors: Barbara Murphy, Philip J. O'Connell
  • Publication number: 20180292395
    Abstract: A method for identifying a kidney transplant recipient at an increased risk of developing interstitial fibrosis or tubular atrophy which comprises obtaining a post-transplant urine sample from the kidney transplant recipient; measuring the level of clusterin in the urine sample; comparing the level of clusterin in the patient sample to the level of clusterin in a control sample from the urine of a non-fibrotic kidney transplant recipient; diagnosing a kidney transplant recipient with a clusterin level that is significantly higher than the clusterin level in the control as being at an increased risk of developing interstitial fibrosis or tubular atrophy.
    Type: Application
    Filed: November 13, 2017
    Publication date: October 11, 2018
    Inventors: Barbara Murphy, Philip J. O'Connell
  • Patent number: 9816985
    Abstract: A method for identifying a kidney transplant recipient at an increased risk of developing interstitial fibrosis or tubular atrophy which comprises obtaining a post-transplant urine sample from the kidney transplant recipient; measuring the level of clusterin in the urine sample; comparing the level of clusterin in the patient sample to the level of clusterin in a control sample from the urine of a non-fibrotic kidney transplant recipient; diagnosing a kidney transplant recipient with a clusterin level that is significantly higher than the clusterin level in the control as being at an increased risk of developing interstitial fibrosis or tubular atrophy.
    Type: Grant
    Filed: April 17, 2013
    Date of Patent: November 14, 2017
    Assignees: Icahn School of Medicine at Mount Sinai, Westmead Institure For Medical Research, Western Sydney Local Health District
    Inventors: Barbara Murphy, Philip J. O'Connell
  • Publication number: 20150133378
    Abstract: A method for identifying a kidney transplant recipient at an increased risk of developing interstitial fibrosis or tubular atrophy which comprises obtaining a post-transplant urine sample from the kidney transplant recipient; measuring the level of clusterin in the urine sample; comparing the level of clusterin in the patient sample to the level of clusterin in a control sample from the urine of a non-fibrotic kidney transplant recipient; diagnosing a kidney transplant recipient with a clusterin level that is significantly higher than the clusterin level in the control as being at an increased risk of developing interstitial fibrosis or tubular atrophy.
    Type: Application
    Filed: April 17, 2013
    Publication date: May 14, 2015
    Inventors: Barbara Murphy, Philip J. O'Connell
  • Patent number: 4848105
    Abstract: A clothes washing machine of the vertical axis type has a self-cleaning lint filter integral with the spin tub. The spin tub is formed as a unitary piece from plastic material, and includes a central hub and radially outer bottom wall which are interconnected by a plurality of radially extending ribs. The ribs have spaces between them defining an annular gap, and an annular perforated lint filter is secured in the gap. An oscillating agitator within the spin tub has downwardly projecting vanes on the lower outer surface of its skirt portion which, as the agitator oscillates, cooperate with the spin tub ribs to form a pumping action to pump liquid upwardly through the lint filter and out to the interior of the spin tub. When the agitator and spin tub go into a spin mode, the centrifugal force washes the lint on the underside of the lint filter off into the fluid being pumped to drain.
    Type: Grant
    Filed: July 25, 1988
    Date of Patent: July 18, 1989
    Assignee: White Consolidated Industries, Inc.
    Inventors: Philip J. O'Connell, Raymond W. Rummel