Abstract: The present invention relates to encapsulated microfluidic packages and methods thereof. In particular embodiments, the package includes a device, a cradle configured to support the device, and a lid having a bonding surface configured to provide a fluidic seal between itself and the device and/or cradle. Other package configurations, as well as methods for making such fluidic seals, are described herein.

Abstract: A microneedle device comprising a hollow microneedle protruding from the rim of an outer open holder can be used for the extraction of interstitial fluid (ISF). Dermal ISF can be extracted with the microneedle device with minimal pain and no blistering for human subjects. Extracted ISF volumes are sufficient for determining transcriptome and proteome signatures. Similar profiles in ISF, serum, and plasma samples, suggest that ISF can be a proxy for direct blood sampling. This minimally-invasive microneedle device enables real-time health monitoring applications using extracted ISF.

Abstract: The present invention relates to encapsulated microfluidic packages and methods thereof. In particular embodiments, the package includes a device, a cradle configured to support the device, and a lid having a bonding surface configured to provide a fluidic seal between itself and the device and/or cradle. Other package configurations, as well as methods for making such fluidic seals, are described herein.

Abstract: The present invention relates to encapsulated microfluidic packages and methods thereof. In particular embodiments, the package includes a device, a cradle configured to support the device, and a lid having a bonding surface configured to provide a fluidic seal between itself and the device and/or cradle. Other package configurations, as well as methods for making such fluidic seals, are described herein.

Abstract: A microneedle device comprising a hollow microneedle protruding from the rim of an outer open holder can be used for the extraction of interstitial fluid (ISF). Dermal ISF can be extracted with the microneedle device with minimal pain and no blistering for human subjects. Extracted ISF volumes are sufficient for determining transcriptome and proteome signatures. Similar profiles in ISF, serum, and plasma samples, suggest that ISF can be a proxy for direct blood sampling. This minimally-invasive microneedle device enables real-time health monitoring applications using extracted ISF.

Abstract: The present invention relates to encapsulated microfluidic packages and methods thereof. In particular embodiments, the package includes a device, a cradle configured to support the device, and a lid having a bonding surface configured to provide a fluidic seal between itself and the device and/or cradle. Other package configurations, as well as methods for making such fluidic seals, are described herein.

Abstract: The present invention relates to methods of using an aqueous composition or dispersion containing a water-soluble or water-dispersible synthetic polymer, and compositions formed thereof. The aqueous composition or dispersion is added to agricultural spray compositions, ink compositions, deicing or anti-icing compositions, latex paint and coating compositions, cleaner compositions, adhesives, fire-extinguishing chemical compositions, hydro-metallurgy/electro-winning compositions, compositions having organosilanes, personal care compositions, water-based hydraulic compositions, dust control compositions, and textile finish compositions, to impart properties including aerosol control, spatter control, shear stability, rheology control, transfer efficiency, oil/water reduction, sling control, emollient performance, film forming capability, surface activity, encapsulent ability, lubricity, thickening, and anti-wear capability, to the resultant composition formed thereof.

Abstract: A friction-modifying additive composition for a slideway lubricant comprising a mixture of at least one polymeric ester of certain dibasic and monobasic acids with selected organo phosphorus compounds.

Abstract: The present invention relates to a hydraulic fluid composition comprising: (a) a base fluid and (b) as an anti-mist additive, an alkylene-vinyl ester copolymer having a molecular weight of between about 5,000 and about 100,000 and soluble in said base fluid. In another aspect, the present invention relates to a process for imparting flame retardancy and reduced wear characteristics to a hydraulic system which comprises adding to the hydraulic system the above-identified hydraulic fluid composition.

Abstract: A heat transfer composition comprising a heat transfer medium and a lubricant, wherein said heat transfer medium is a low boiling organic compound and wherein said lubricant is a halogenated polyoxyalkylene monoalcohol having the empirical structural formula:R.sub.1 X.sub.m (OR.sub.2).sub.n --OHwherein R.sub.1 and R.sub.2 are independently selected from the group having 1 to 18 carbon atoms, an aryl group having from 6 to 18 carbon atoms, and combinations thereof, X is a halogen, m is an integer of between 1 and 37, and n is an integer from 5-350. Also claimed is the process for making the lubricant and the lubricant composition itself.

Abstract: Disclosed is an improved water-based hydraulic fluid composition which comprises an aqueous composition having a viscosity of at least 5 centistokes at 40.degree. C. which contains up to about 95 percent by weight of water, at least 0.1 percent by weight of a carboxylic acid lubricity agent, and an effective amount of at least one selected anti-wear additive; wherein the improvement comprises:said anti-wear agent comprising the combination of:(a) mono-, di-, or trihydroxy-substituted aromatic compound; with(b) an aromatic compound substituted with one to three electron-withdrawing substituents, wherein said electron-withdrawing substituents are selected from the group consisting of cyano, sulfo, and mixtures thereof.

Abstract: Disclosed is an improved water-based hydraulic fluid composition which comprises an aqueous composition having a viscosity of at least 5 centistokes at 40.degree. C. which contains up to about 95 percent by weight of water, at least 0.1 percent by weight of a carboxylic acid lubricity agent, and an effective amount of at least one selected anti-wear additive; wherein the improvement comprises:said anti-wear agent comprising the combination of:(a) an aromatic compound containing one to three electron-releasing substituent components, wherein said electron-releasing substituents are selected from the group consisting of amino, alkyl-substituted amino having 1 to about 12 carbon atoms, amido groups of the formula --NHC(.dbd.