Patents by Inventor Philip Turnbull

Philip Turnbull has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GLP-1 receptor modulators
    Patent number: 11530205
    Abstract: Compounds are provided that modulate the glucagon-like peptide 1 (GLP-1) receptor, as well as products containing such compounds, and methods of their use and synthesis. Such compounds have the structure of Formula (I) below: (I) or pharmaceutically acceptable salts thereof, wherein A, J, W1, Y, Z, R1, R2, R3 and R4 are as defined herein.
    Type: Grant
    Filed: April 26, 2018
    Date of Patent: December 20, 2022
    Assignee: Receptos LLC
    Inventors: Junko Tamiya, Philip Turnbull, Brahmachary Enugurthi, Liming Huang, Adam R. Yeager, Thomas Fowler, Greg P. Iacobini, Matthew Richard Crittall
  • SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATOR
    Publication number: 20220227722
    Abstract: A compound is provided having following structure Compound (1): or a pharmaceutically acceptable salt, homolog, hydrate or solvate thereof. Also provided is a pharmaceutical composition comprising Compound (1) or a pharmaceutically acceptable salt, homolog, hydrate or solvate thereof, in combination with a pharmaceutically acceptable carrier or diluent.
    Type: Application
    Filed: March 27, 2020
    Publication date: July 21, 2022
    Inventors: Philip TURNBULL, Esther MARTINBOROUGH, Maurice MARSINI
  • SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS
    Publication number: 20220194971
    Abstract: Compounds are provided having the structure of Formula (I) or (II) or a pharmaceutically acceptable salt, homolog, hydrate or solvate thereof, wherein Ra, Rd and Re are as defined herein. Such compounds serve as modulators of the sphingosine-1-phosphate receptor, and have utility for treatment of a malcondition for which activation of this receptor is medically indicated.
    Type: Application
    Filed: March 27, 2020
    Publication date: June 23, 2022
    Inventors: Philip Turnbull, Roger Bakale, Jeff Schkeryantz, Maurice Marsini
  • SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS
    Publication number: 20220194908
    Abstract: Compounds are provided having the structure of Formula (I), or a pharmaceutically acceptable salt, homolog, hydrate or solvate thereof, wherein Rb1 and Rb2 are as defined herein. Such compounds serve as modulators of the sphingosine-1-phosphate receptor, and have utility for treatment of a malcondition for which activation of this receptor is medically indicated.
    Type: Application
    Filed: March 27, 2020
    Publication date: June 23, 2022
    Inventors: Philip Turnbull, Roger Bakale, Maurice Marsini
  • SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS
    Publication number: 20220144788
    Abstract: Compounds are provided having the structure of Formula (I) or a pharmaceutically acceptable salt, homolog, hydrate or solvate thereof, wherein Ra is as defined herein. Such compounds serve as modulators of the sphingosine-1-phosphate receptor, and have utility for treatment of a malcondition for which activation of this receptor is medically indicated.
    Type: Application
    Filed: March 27, 2020
    Publication date: May 12, 2022
    Inventors: Philip Turnbull, Roger Bakale, Jeff Schkeryantz, Maurice Marsini
  • NOVEL GLP-1 RECEPTOR MODULATORS
    Publication number: 20210371409
    Abstract: Compounds are provided that modulate the glucagon-like peptide 1 (GLP-1) receptor, as well as products containing such compounds, and methods of their use and synthesis. Such compounds have the structure of Formula (I) below: (I) or pharmaceutically acceptable salts thereof, wherein A, J, W1, Y, Z, R1, R2, R3 and R4 are as defined herein.
    Type: Application
    Filed: April 26, 2018
    Publication date: December 2, 2021
    Inventors: Junko Tamiya, Philip Turnbull, Brahmachary Enugurthi, Liming Huang, Adam R. Yeager, Thomas Fowler, Greg P. Iacobini, Matthew Richard Crittall
  • Dimethylaminoethanol salt of a GLP-1 receptor modulator
    Patent number: 11066395
    Abstract: Crystalline 2-hydroxy-N,N-dimethylethanaminium 1-(2-(5-(tert-butyl)-thiophene-2-carboxamido)-3-(4-(5-(4?-ethyl-[1,1?-bi(cyclohexan)]-3-en-4-yl)pyrimidin-2-yl)phenyl)propanoyl)azetidine-3-carboxylate salt, and methods related to synthesis and therapeutic use of the same.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: July 20, 2021
    Assignee: RECEPTOS LLC
    Inventors: Ephraim Vidal, Roger Bakale, Philip Turnbull, David Moser, Andrew Robbins, Craig Grant
  • CXCR3 receptor agonists
    Patent number: 11040954
    Abstract: Compounds are provided having the structure of the following Formula I: where R, R1, R2, R3a and R3b are as defined herein. Pharmaceutical compositions comprising such compounds, as well as methods related to their manufacture and use, are also provided.
    Type: Grant
    Filed: May 11, 2020
    Date of Patent: June 22, 2021
    Assignee: RECEPTOS LLC
    Inventors: Adam Yeager, Philip Turnbull, Lin Zhang, Junhua Fan, Junko Tamiya, Marcos Steinberg, Tom Fowler, Hanae Benelkebir, Raffaele Pasceri, Maria Ieva, Kevan Grant, Yang Tran
  • DIMETHYLAMINOETHANOL SALT OF A GLP-1 RECEPTOR MODULATOR
    Publication number: 20200131164
    Abstract: Crystalline 2-hydroxy-N,N-dimethylethanaminium 1-(2-(5-(tert-butyl)-thiophene-2-carboxamido)-3-(4-(5-(4?-ethyl-[1,1?-bi(cyclohexan)]-3-en-4-yl)pyrimidin-2-yl)phenyl)propanoyl)azetidine-3-carboxylate salt, and methods related to synthesis and therapeutic use of the same.
    Type: Application
    Filed: September 29, 2017
    Publication date: April 30, 2020
    Inventors: Ephraim Vidal, Roger Bakale, Philip Turnbull, David Moser, Andrew Robbins, Craig Grant
  • CXCR3 RECEPTOR AGONISTS
    Publication number: 20190345133
    Abstract: Compounds are provided having the structure of the following Formula I: where R, R1, R2, R3a and R3b are as defined herein. Pharmaceutical compositions comprising such compounds, as well as methods related to their manufacture and use, are also provided.
    Type: Application
    Filed: August 31, 2017
    Publication date: November 14, 2019
    Inventors: Adam Yeager, Philip Turnbull, Lin Zhang, Junhua Fan, Junko Tamiya, Marcos Steinberg, Tom Fowler, Hanae Benelkebir, Raffaele Pasceri, Maria Ieva, Kevan Grant, Yang Tran
  • CHEMICAL COMPOUNDS
    Publication number: 20070276000
    Abstract: The present invention relates to cycloalkylidene compounds with a variety of therapeutic uses, more particularly novel naphthalene compounds that are particularly useful for selective estrogen modulation.
    Type: Application
    Filed: June 21, 2005
    Publication date: November 29, 2007
    Inventors: Dennis Heyer, Jing Fang, Frank Navas III, Subba Katamreddy, Jennifer Peckham, Philip Turnbull, Aaron Miller, Adwoa Akwabi-Ameyan, Charles Dadswell
  • Aniline derivatives as selective androgen receptor modulators
    Publication number: 20070191479
    Abstract: This invention relates to non-steroidal compounds that are modulators of androgen, glucocorticoid, mineralocorticoid, and progesterone receptors, and also to the methods for the making and use of such compounds.
    Type: Application
    Filed: March 3, 2005
    Publication date: August 16, 2007
    Inventors: Philip Turnbull, Rodolfo Cadilla, David Cowan, Andrew Larkin, Istvan Kaldor, Eugene Stewart
  • Chemical compounds
    Publication number: 20060148893
    Abstract: This invention relates to non-steroidal compounds that are or are believed to be modulators of androgen, glucocorticoid, mineralocorticoid, and progesterone receptors, and also to the methods for the making and use of such compounds.
    Type: Application
    Filed: June 9, 2004
    Publication date: July 6, 2006
    Inventors: Jean-Baptiste Blanc, Rodolfo Cadilla, David Cowan, Istvan Kaldor, Andrew Larkin, Eugene Stewart, Ryan Trump, Philip Turnbull
  • Chemical compounds
    Publication number: 20060142387
    Abstract: This invention relates to non-steroidal compounds that are modulators of androgen, glucocorticoid, mineralocorticoid, and progesterone receptors, and also to the methods for the making and use of such compounds.
    Type: Application
    Filed: June 9, 2004
    Publication date: June 29, 2006
    Inventors: Rodolfo Cadilla, Andrew Larkin, Eugene Stewart, Ryan Trump, Philip Turnbull
  • Condensed heterocyclic compounds as calcitonin agonists
    Publication number: 20050107419
    Abstract: The present invention relates to novel fused heterocyclic ring system compounds and methods for their use in the treatment and prevention of diseases or conditions.
    Type: Application
    Filed: February 24, 2003
    Publication date: May 19, 2005
    Inventors: Ashok Bhandari, Eric Boros, David Cowan, Anthony Handlon, Clifton Hyman, Jeffrey Oplinger, Michael Rabinowitz, Philip Turnbull