Patents by Inventor Philip W. Hammond

Philip W. Hammond has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Optimized anti-CD30 antibodies
    Patent number: 9574006
    Abstract: An antibody that targets CD30, wherein the antibody comprises at least one modification relative to a parent antibody and the antibody binds with altered affinity to an Fc?R or alters effector function as compared to the parent antibody. Also disclosed are methods of using the anti-CD30 antibody.
    Type: Grant
    Filed: June 17, 2011
    Date of Patent: February 21, 2017
    Assignee: Xencor, Inc.
    Inventors: Gregory Alan Lazar, John R. Desjarlais, Philip W. Hammond, David F. Carmichael, Bao-lu Chen, Seung Y. Chu, Sher Bahadur Karki, Lori Kunkel
  • Hybridization assay detection probes for detecting human papilloma virus in a sample
    Patent number: 9194008
    Abstract: Hybridization assay detection probes targeted to HPV Type 16 nucleic acid sequences which are particularly useful to aid in detecting HPV type 16 are described. The oligonucleotides can aid in detecting HPV Type 16 by acting singly or as part of a detection probe mixture. Compositions, reaction mixtures and methods of use are provided.
    Type: Grant
    Filed: June 21, 2013
    Date of Patent: November 24, 2015
    Assignee: Gen-Probe Incorporated
    Inventors: Patricia Gordon, Nick M. Carter, Steven T. Brentano, Philip W. Hammond
  • HYBRIDIZATION ASSAY DETECTION PROBES FOR DETECTING HUMAN PAPILLOMA VIRUS IN A SAMPLE
    Publication number: 20150037785
    Abstract: Hybridization assay detection probes targeted to HPV Type 16 nucleic acid sequences which are particularly useful to aid in detecting HPV type 16 are described. The oligonucleotides can aid in detecting HPV Type 16 by acting singly or as part of a detection probe mixture. Compositions, reaction mixtures and methods of use are provided.
    Type: Application
    Filed: June 21, 2013
    Publication date: February 5, 2015
    Inventors: Patricia GORDON, Nick M. CARTER, Steven T. BRENTANO, Philip W. HAMMOND
  • Oligonucleotides for detecting human papilloma virus in a test sample
    Patent number: 8501410
    Abstract: Oligonucleotides targeted to HPV Type 16 and/or Type 18 nucleic acid sequences which are particularly useful to aid in detecting HPV type 16 and or 18 are described. The oligonucleotides can aid in detecting HPV Type 16 and/or Type 18 in different ways such as by acting as hybridization assay probes, helper probes, and/or amplification primers.
    Type: Grant
    Filed: December 10, 2010
    Date of Patent: August 6, 2013
    Assignee: Gen-Probe Incorporated
    Inventors: Patricia Gordon, Nick M. Carter, Steven T. Brentano, Philip W. Hammond
  • Optimized Anti-CD30 Antibodies
    Publication number: 20120014943
    Abstract: An antibody that targets CD30, wherein the antibody comprises at least one modification relative to a parent antibody and the antibody binds with altered affinity to an Fc?R or alters effector function as compared to the parent antibody. Also disclosed are methods of using the anti-CD30 antibody.
    Type: Application
    Filed: June 17, 2011
    Publication date: January 19, 2012
    Applicant: Xencor, Inc.
    Inventors: Gregory Alan Lazar, John R. Desjarlais, Philip W. Hammond, David F. Carmichael, Bao-Iu Chen, Seung Y. Chu, Sher Bahadur Karki, Lori Kunkel
  • METHODS OF GENERATING VARIANT PROTEINS WITH INCREASED HOST STRING CONTENT AND COMPOSITIONS THEREOF
    Publication number: 20110236969
    Abstract: The present invention relates to novel methods for generating variant proteins with increased host string content, and proteins that are engineered using these methods.
    Type: Application
    Filed: March 21, 2011
    Publication date: September 29, 2011
    Applicant: Xencor, Inc.
    Inventors: Gregory Alan Lazar, John R. Desjarlais, Philip W. Hammond
  • Oligonucleotides For Detecting Human Papilloma Virus In A Test Sample
    Publication number: 20110223584
    Abstract: Oligonucleotides targeted to HPV Type 16 and/or Type 18 nucleic acid sequences which are particularly useful to aid in detecting HPV type 16 and or 18 are described. The oligonucleotides can aid in detecting HPV Type 16 and/or Type 18 in different ways such as by acting as hybridization assay probes, helper probes, and/or amplification primers.
    Type: Application
    Filed: December 10, 2010
    Publication date: September 15, 2011
    Applicant: GEN-PROBE INCORPORATED
    Inventors: Patricia Gordon, Nick M. Carter, Steven T. Brentano, Philip W. Hammond
  • Optimized anti-CD30 antibodies
    Patent number: 7973136
    Abstract: An antibody that targets CD30, wherein the antibody comprises at least one modification relative to a parent antibody and the antibody binds with altered affinity to an FcgR or alters effector function as compared to the parent antibody. Also disclosed are methods of using the anti-CD30 antibody.
    Type: Grant
    Filed: October 6, 2006
    Date of Patent: July 5, 2011
    Assignee: Xencor, Inc.
    Inventors: Gregory Alan Lazar, John R. Desjarlais, Philip W. Hammond, David F. Carmichael, Bao-lu Chen, Seung Y. Chu, Sher Bahadur Karki, Lori Kunkel
  • Methods of generating variant proteins with increased host string content
    Patent number: 7930107
    Abstract: The present invention relates to novel methods for generating variant proteins with increased host string content, and proteins that are engineered using these methods.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: April 19, 2011
    Assignee: Xencor, Inc.
    Inventors: Gregory Alan Lazar, John R. Desjarlais, Philip W. Hammond
  • HUMAN ANTI-CANCER ANTIBODIES
    Publication number: 20110064743
    Abstract: The present invention provides novel human anti-cancer antibodies and related compositions and methods. These antibodies are used in the diagnosis and treatment of cancer.
    Type: Application
    Filed: September 9, 2010
    Publication date: March 17, 2011
    Inventors: PHILIP W. HAMMOND, ANNE-RENEE VAN DER VUURST DE VRIES, LARRY W. TJOELKER, MATTHEW MOYLE
  • Oligonucleotides for detecting human papilloma virus in a test sample
    Patent number: 7875441
    Abstract: Oligonucleotides targeted to HPV Type 16 and/or Type 18 nucleic acid sequences which are particularly useful to aid in detecting HPV type 16 and or 18 are described. The oligonucleotides can aid in detecting HPV Type 16 and/or Type 18 in different ways such as by acting as hybridization assay probes, helper probes, and/or amplification primers.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: January 25, 2011
    Assignee: Gen-Probe Incorporated
    Inventors: Patricia Gordon, Nick M. Carter, Steven T. Brentano, Philip W. Hammond
  • Methods of Generating Variant Proteins with Increased Host String Content
    Publication number: 20100190247
    Abstract: The present invention relates to novel methods for generating variant proteins with increased host string content, and proteins that are engineered using these methods.
    Type: Application
    Filed: March 12, 2010
    Publication date: July 29, 2010
    Applicant: Xencor, Inc.
    Inventors: Gregory ALAN Lazar, John R. Desjarlais, Philip W. Hammond
  • Methods of generating variant antibodies with increased host string content
    Patent number: 7657380
    Abstract: The present invention relates to novel methods for generating variant proteins with increased host string content by comparing a parent protein sequence with two or more natural protein sequences from a host species, analyzing one or more amino acid strings of the parent protein sequence with a structurally corresponding amino acid string of each of said natural protein sequences, substituting one or more amino acid strings of the parent protein sequence with a structurally corresponding amino acid string of one of the two or more natural protein sequences on an amino acid string by amino acid string basis so that the variant protein has increased host string content, and, synthesizing and screening the variant protein.
    Type: Grant
    Filed: December 3, 2004
    Date of Patent: February 2, 2010
    Assignee: Xencor, Inc.
    Inventors: Gregory Alan Lazar, John R. Desjarlais, Philip W. Hammond
  • Oligonucleotides for use in determining the presence of human papilloma virus in a test sample
    Patent number: 7470512
    Abstract: The present invention describes oligonucleotides targeted to HPV Type 16 and/or Type 18 nucleic acid sequences which are particularly useful to aid in detecting HPV type 16 and or 18. The oligonucleotides can aid in detecting HPV Type 16 and/or Type 18 in different ways such as by acting as hybridization assay probes, helper probes, and/or amplification primers.
    Type: Grant
    Filed: June 23, 2003
    Date of Patent: December 30, 2008
    Assignee: Gen-Probe Incorporated
    Inventors: Patricia Gordon, Nick M. Carter, Steven T. Brentano, Philip W. Hammond
  • Oligonucleotides For Detecting Human Papilloma Virus In A Test Sample
    Publication number: 20080311560
    Abstract: Oligonucleotides targeted to HPV Type 16 and/or Type 18 nucleic acid sequences which are particularly useful to aid in detecting HPV type 16 and or 18 are described. The oligonucleotides can aid in detecting HPV Type 16 and/or Type 18 in different ways such as by acting as hybridization assay probes, helper probes, and/or amplification primers.
    Type: Application
    Filed: October 30, 2007
    Publication date: December 18, 2008
    Inventors: Patricia GORDON, Nick M. Carter, Steven T. Brentano, Philip W. Hammond
  • Optimized Anti-Cd30 Antibodies
    Publication number: 20080267976
    Abstract: An antibody that targets CD30, wherein the antibody comprises at least one modification relative to a parent antibody and the antibody binds with altered affinity to an FcgR or alters effector function as compared to the parent antibody. Also disclosed are methods of using the anti-CD30 antibody.
    Type: Application
    Filed: October 6, 2006
    Publication date: October 30, 2008
    Inventors: Gregory Alan Lazar, John R. Desjarlais, Philip W. Hammond, David F. Carmichael, Bao-lu Chen, Seung Y. Chu, Sher Bahadur Karki, Lori Kunkel
  • METHOD OF TREATMENT OF TH2-MEDIATED CONDITIONS USING OPTIMIZED ANTI-CD30 ANTIBODIES
    Publication number: 20080206242
    Abstract: A method of treating Th2-mediated conditions, e.g., atopic conditions, e.g., atopic asthma and/or atopic dermatitis, using effective amount of an antibody that targets CD30, where the antibody has at least one modification relative to a parent antibody and the antibody binds with altered affinity to an Fc?R or alters effector function as compared to the parent antibody.
    Type: Application
    Filed: February 1, 2008
    Publication date: August 28, 2008
    Applicant: Xencor, Inc.
    Inventors: Christopher E. Lawrence, Philip W. Hammond
  • Methods of generating variant proteins with increased host string content and compositions thereof
    Publication number: 20080167449
    Abstract: The present invention relates to novel methods for generating variant proteins with increased host string content, and proteins that are engineered using these methods.
    Type: Application
    Filed: October 31, 2007
    Publication date: July 10, 2008
    Applicant: Xencor, Inc.
    Inventors: Gregory Alan Lazar, John R. Desjarlais, Philip W. Hammond
  • Oligonucleotides for use in determining the presence of human papilloma virus in a test sample
    Patent number: 7355034
    Abstract: The present invention describes oligonucleotides targeted to HPV Type 16 and/or Type 18 nucleic acid sequences which are particularly useful to aid in detecting HPV type 16 and or 18. The oligonucleotides can aid in detecting HPV Type 16 and/or Type 18 in different ways such as by acting as hybridization assay probes, helper probes, and/or amplification primers.
    Type: Grant
    Filed: June 26, 2003
    Date of Patent: April 8, 2008
    Assignee: Gen-Probe Incorporated
    Inventors: Patricia Gordon, Nick M. Carter, Steven T. Brentano, Philip W. Hammond
  • Oligonucleotides for nucleic acid amplification and for the detection of
    Patent number: 7009041
    Abstract: A method, composition and kit for synthesizing multiple copies of a target nucleic acid sequence autocatalytically under conditions of substantially constant temperature, ionic strength, and pH are provided in which multiple RNA copies of the target sequence autocatalytically generate additional copies using a mixture of blocked and unblocked primers and/or promoter-primers to initiate DNA and RNA synthesis, preferably with reduced non-specific product formation. The invention is useful for generating copies of a nucleic acid target sequence for purposes that include assays to quantitate specific nucleic acid sequences in clinical, environmental, forensic and similar samples, cloning and generating probes.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: March 7, 2006
    Assignee: Gen-Probe Incorporated
    Inventors: Sherrol H. McDonough, Daniel L. Kacian, Nanibhushan Dattagupta, Diane L. McAllister, Philip W. Hammond, Thomas B. Ryder