Abstract: Provided is a method and apparatus for placing a valve (14) in a tubular organ having a greater diameter than the valve, comprising: an expandable tubular adapter (10) having an outer portion with a diameter suitable for contacting the inner walls of the tubular organ, and an inner portion with a diameter suitable for placement of the valve; a valve mounted within the inner portion of the adapter; and a system for placing a valved vascular segment in a tubular organ having a greater inner diameter than the outer diameter of the vascular segment, comprising: an expandable tubular adapter having an outer portion with a diameter suitable for contacting the inner walls of the tubular organ, and an inner portion with a diameter suitable for placement of the valve; an expandable valved vascular segment, expandable to the diameter of the inner portion of the adapter.

Abstract: A system for percutaneously inserting a prosthesis containing a biological replacement for a defective valve into an implantation site through a body lumen. The system contains a balloon catheter upon which a collapsable stent containing a venous valvular replacement is mounted. A protective shield is slidably mounted upon the catheter that is movable between a closed position over the balloon and an open position wherein the balloon can be inflated to expand the stent. A central lumen runs through the catheter that is formed of stainless steel. The central lumen provides a one to one torque ratio between the proximal end of the catheter and the distal end to enhance the steerability of the catheter. The vein of the replacement is reduced in thickness between 50% and 90% of its original size thereby considerably reducing the size of the replacement package when the stem is collapsed upon the balloon of the catheter.

Abstract: A system for percutaneously inserting a prosthesis containing a biological replacement for a defective valve into an implantation site through a body lumen. The system contains a balloon catheter upon which a collapsable stent containing a venous valvular replacement is mounted. A protective shield is slidably mounted upon the catheter that is movable between a closed position over the balloon and an open position wherein the balloon can be inflated to expand the stent. A central lumen runs through the catheter that is formed of stainless steel. The central lumen provides a one to one torque ratio between the proximal end of the catheter and the distal end to enhance the steerability of the catheter. The vein of the replacement is reduced in thickness between 50% and 90% of its original size thereby considerably reducing the size of the replacement package when the stem is collapsed upon the balloon of the catheter.

Abstract: A prosthesis device for percutaneous implantation that includes an expandable stent and a biological venous valvular replacement for a defective valve mounted inside the expanded stent. The wall thickness of the vein is reduced to a diameter that is about equal to the inside diameter of the expanded stent and is sutured to the inside of the expanded stent so that the vein is supported in a fully opened circular configuration.