Patents by Inventor Phillip R. Hawkins
Phillip R. Hawkins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8008027Abstract: The present invention provides nucleotide and amino acid sequences that identify and encode a novel expressed chemokine (ADEC) from inflamed adenoid tissue. The present invention also provides for antisense molecules to the nucleotide sequences which encode ADEC, expression vectors for the production of purified ADEC, antibodies capable of binding specifically to ADEC, hybridization probes or oligonucleotides for the detection of ADEC-encoding nucleotide sequences, genetically engineered host cells for the expression of ADEC, diagnostic tests for inflammation or disease based on ADEC-encoding nucleic acid molecules or antibodies capable of binding specifically to ADEC.Type: GrantFiled: March 24, 2010Date of Patent: August 30, 2011Assignee: Incyte CorporationInventors: Karl J. Guegler, Phillip R. Hawkins, Craig G. Wilde, Jeffrey J. Seilhamer
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Publication number: 20100279333Abstract: The present invention provides nucleotide and amino acid sequences that identify and encode a novel expressed chemokine (ADEC) from inflamed adenoid tissue. The present invention also provides for antisense molecules to the nucleotide sequences which encode ADEC, expression vectors for the production of purified ADEC, antibodies capable of binding specifically to ADEC, hybridization probes or oligonucleotides for the detection of ADEC-encoding nucleotide sequences, genetically engineered host cells for the expression of ADEC, diagnostic tests for inflammation or disease based on ADEC-encoding nucleic acid molecules or antibodies capable of binding specifically to ADEC.Type: ApplicationFiled: March 24, 2010Publication date: November 4, 2010Inventors: KARL J. GUEGLER, PHILLIP R. HAWKINS, CRAIG G. WILDE, JEFFREY J. SEILHAMER
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Patent number: 7708984Abstract: The present invention provides nucleotide and amino acid sequences that identify and encode a novel expressed chemokine (ADEC) from inflamed adenoid tissue. The present invention also provides for antisense molecules to the nucleotide sequences which encode ADEC, expression vectors for the production of purified ADEC, antibodies capable of binding specifically to ADEC, hybridization probes or oligonucleotides for the detection of ADEC-encoding nucleotide sequences, genetically engineered host cells for the expression of ADEC, diagnostic tests for inflammation or disease based on ADEC-encoding nucleic acid molecules or antibodies capable of binding specifically to ADEC.Type: GrantFiled: June 4, 2007Date of Patent: May 4, 2010Assignee: Incyte CorporationInventors: Karl J. Guegler, Phillip R. Hawkins, Craig G. Wilde, Jeffrey J. Seilhamer
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Publication number: 20080138346Abstract: The present invention provides nucleotide and amino acid sequences that identify and encode a novel expressed chemokine (ADEC) from inflamed adenoid tissue. The present invention also provides for antisense molecules to the nucleotide sequences which encode ADEC, expression vectors for the production of purified ADEC, antibodies capable of binding specifically to ADEC, hybridization probes or oligonucleotides for the detection of ADEC-encoding nucleotide sequences, genetically engineered host cells for the expression of ADEC, diagnostic tests for inflammation or disease based on ADEC-encoding nucleic acid molecules or antibodies capable of binding specifically to ADEC.Type: ApplicationFiled: June 4, 2007Publication date: June 12, 2008Inventors: Karl J. Guegler, Phillip R. Hawkins, Craig G. Wilde, Jeffrey J. Seilhamer
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Patent number: 7378492Abstract: Various embodiments of the invention provide human receptors and membrane-associated proteins (REMAP) and Q polynucleotides which identify and encode REMAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.Type: GrantFiled: February 18, 2003Date of Patent: May 27, 2008Assignee: Incyte CorporationInventors: Narinder K. Chawla, Henry Yue, Thomas W. Richardson, Joseph P. Marquis, Patricia M. Lehr-Mason, Ann E. Gorvad, Shanya D. Becha, Amy E. Kable, Anita Swarnakar, Pei Jin, Phillip R. Hawkins, David Chien, Jayalaxmi Ramkumar, Uyen K. Tran, April J. A. Hafalia, Mariah R. Baughn, Soo Yeun Lee, Xin Jiang, Alan A. Jackson, Reena Khare, Sean A. Bulloch
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Patent number: 7235239Abstract: The present invention provides nucleotide and amino acid sequences that identify and encode a novel expressed chemokine (ADEC) from inflamed adenoid tissue. The present invention also provides for antisense molecules to the nucleotide sequences which encode ADEC, expression vectors for the production of purified ADEC, antibodies capable of binding specifically to ADEC, hybridization probes or oligonucleotides for the detection of ADEC-encoding nucleotide sequences, genetically engineered host cells for the expression of ADEC, diagnostic tests for inflammation or disease based on ADEC-encoding nucleic acid molecules or antibodies capable of binding specifically to ADEC.Type: GrantFiled: October 28, 2003Date of Patent: June 26, 2007Assignee: Incyte IncorporationInventors: Karl J Guegler, Phillip R Hawkins, Craig G Wilde, deceased, Jeffrey J Seilhamer, deceased
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Publication number: 20040086975Abstract: The present invention provides nucleotide and amino acid sequences that identify and encode a novel expressed chemokine (ADEC) from inflamed adenoid tissue. The present invention also provides for antisense molecules to the nucleotide sequences which encode ADEC, expression vectors for the production of purified ADEC, antibodies capable of binding specifically to ADEC, hybridization probes or oligonucleotides for the detection of ADEC-encoding nucleotide sequences, genetically engineered host cells for the expression of ADEC, diagnostic tests for inflammation or disease based on ADEC-encoding nucleic acid molecules or antibodies capable of binding specifically to ADEC.Type: ApplicationFiled: October 28, 2003Publication date: May 6, 2004Applicant: Incyte CorporationInventors: Karl J. Guegler, Phillip R. Hawkins, Craig G. Wilde, Jeffrey J. Seilhamer
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Patent number: 6692920Abstract: The present invention provides nucleotide and amino acid sequences that identify and encode a novel expressed chemokine (ADEC) from inflamed adenoid tissue. The present invention also provides for antisense molecules to the nucleotide sequences which encode ADEC, expression vectors for the production of purified ADEC, antibodies capable of binding specifically to ADEC, hybridization probes or oligonucleotides for the detection of ADEC-encoding nucleotide sequences, genetically engineered host cells for the expression of ADEC, diagnostic tests for inflammation or disease based on ADEC-encoding nucleic acid molecules or antibodies capable of binding specifically to ADEC.Type: GrantFiled: June 5, 2000Date of Patent: February 17, 2004Assignee: Incyte CorporationInventors: Karl J. Guegler, Phillip R. Hawkins, Craig G. Wilde, Jeffrey J. Seilhamer
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Patent number: 6677126Abstract: The invention provides a human translational regulator (TRANAC) and polynucleotides which identify and encode TRANAC. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of TRANAC.Type: GrantFiled: March 12, 2002Date of Patent: January 13, 2004Assignee: Incyte CorporationInventors: Jennifer L. Hillman, Phillip R. Hawkins
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Publication number: 20030180931Abstract: The present invention provides nucleotide and amino acid sequences that identify and encode novel cellubrevins (cb). The present invention also provides for antisense molecules to the nucleotide sequences which encode cbs, expression vectors for the production of purified CBs, antibodies capable of binding specifically to CBs, hybridization probes or oligonucleotides for the detecting the induction of CB encoding nucleotide sequences, genetically engineered host cells for the expression of CBs, diagnostic tests for activated, inflamed or diseased cells and/or tissues based on CB-encoding nucleic acid molecules and antibodies capable of binding specifically to CBs.Type: ApplicationFiled: January 29, 2003Publication date: September 25, 2003Applicant: Incyte Genomics, Inc.Inventors: Susan G. Stuart, Phillip R. Hawkins, Jeffrey J. Seilhamer, Lynn E. Murry
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Publication number: 20030096371Abstract: The present invention provides novel human cytokines (designated individually as NHC-1 and NHC-2, and collectively as NHC) and polynucleotides which identify and encode NHC. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding NHC and a method for producing NHC. The invention also provides for use of NHC and agonists, antibodies, or antagonists specifically binding NHC, in the prevention and treatment of diseases associated with expression of NHC. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding NHC for the treatment of diseases associated with the expression of NHC. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding NHC.Type: ApplicationFiled: November 19, 2002Publication date: May 22, 2003Applicant: Incyte Genomics, Inc.Inventors: Olga Bandman, Phillip R. Hawkins, Lynn E. Murry, Surya K. Goli
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Publication number: 20030083468Abstract: The present invention provides nucleotide and amino acid sequences that identify and encode novel expressed chemokines (ECs) from liver and pituitary gland tissues. The present invention also provides for antisense molecules to the nucleotide sequences which encode ECs, expression vectors for the production of purified ECs, antibodies capable of binding specifically to ECs, hybridization probes or oligonucleotides for the detection of EC-encoding nucleotide sequences, genetically engineered host cells for the expression of ECs, diagnostic tests for inflammation or disease based on EC-encoding nucleic acid molecules or antibodies capable of binding specifically to ECs, pharmaceutical compositions to treat inflammation or disease based on EC-encoding nucleic acid molecules or antibodies capable of binding specifically to ECs.Type: ApplicationFiled: November 12, 2002Publication date: May 1, 2003Applicant: Incyte Genomics, Inc.Inventors: Craig G. Wilde, Phillip R. Hawkins, Olga Bandman, Jeffrey J. Seilhamer
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Patent number: 6534275Abstract: The present invention provides nucleotide and amino acid sequences that identify and encode novel cellubrevins (cb). The present invention also provides for antisense molecules to the nucleotide sequences which encode cbs, expression vectors for the production of purified CBs, antibodies capable of binding specifically to CBs, hybridization probes or oligonucleotides for the detecting the induction of CB encoding nucleotide sequences, genetically engineered host cells for the expression of CBs, diagnostic tests for activated, inflamed or diseased cells and/or tissues based on CB-encoding nucleic acid molecules and antibodies capable of binding specifically to CBs.Type: GrantFiled: January 14, 2000Date of Patent: March 18, 2003Assignee: Incyte Genomics, Corp.Inventors: Susan G. Stuart, Phillip R. Hawkins, Jeffrey J. Seilhamer, Lynn E. Murry
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Publication number: 20030022306Abstract: The present invention provides polynucleotides which identify and encode a novel human nm23-like protein (H-nm23). The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequence encoding H-nm23 and for a method for producing the protein. The invention also provides for the use of substantially purified H-nm23 for the for the treatment of diseases associated with the expression of H-nm23. The invention also describes diagnostic assays which utilize diagnostic compositions comprising the polynucleotides which hybridize with naturally occurring sequences encoding H-nm23 and antibodies which specifically bind to the protein.Type: ApplicationFiled: August 28, 2002Publication date: January 30, 2003Applicant: Incyte Genomics, Inc.Inventors: Olga Bandman, Phillip R. Hawkins
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Publication number: 20020177208Abstract: The invention provides a human phospholipase A2 protein PHPLA2 and polynucleotides which identify and encode PHPLA2. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of PHPLA2.Type: ApplicationFiled: April 16, 2002Publication date: November 28, 2002Applicant: Incyte Genomics, Inc.Inventors: Phillip R. Hawkins, Olga Bandman, Karl J. Guegler, Purvi Shah, Neil C. Corley
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Patent number: 6486300Abstract: The present invention provides polynucleotides which identify and encode a novel human nm23-like protein (H-nm23). The invention provides for genetically engineered expression vectors and host cells comprising the nucleic acid sequence encoding H-nm23 and for a method for producing the protein. The invention also provides for the use of substantially purified H-nm23 for the for the treatment of diseases associated with the expression of H-nm23. The invention also describes diagnostic assays which utilize diagnostic compositions comprising the polynucleotides which hybridize with naturally occurring sequences encoding H-nm23 and antibodies which specifically bind to the protein.Type: GrantFiled: December 13, 1999Date of Patent: November 26, 2002Assignee: Incyte Genomics, Inc.Inventors: Olga Bandman, Phillip R. Hawkins
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Publication number: 20020160499Abstract: The present invention provides a human serine carboxypeptidase (CPEPT) and polynucleotides which identify and encode CPEPT. The invention also provides expression vectors, host cells, agonists, antibodies, and antagonists. The invention also provides methods for treating disorders associated with expression of CPEPT.Type: ApplicationFiled: February 25, 2002Publication date: October 31, 2002Applicant: Incyte Pharmaceuticals, Inc.Inventors: Olga Bandman, Phillip R. Hawkins, Jennifer L. Hillman, Preeti Lal, Surya K. Goli
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Publication number: 20020155553Abstract: The present invention provides a human vesicle binding protein (MVBP) and polynucleotides which identify and encode MVBP. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. In addition, the invention provides methods for producing MVBP and for treating or preventing disorders associated with expression of MVBP.Type: ApplicationFiled: July 26, 1999Publication date: October 24, 2002Applicant: INCYTE GENOMICS, INC.Inventors: OLGA BANDMAN, PHILLIP R. HAWKINS
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Publication number: 20020137077Abstract: The present invention relates to a combination comprising a plurality of cDNAs which are differentially expressed in activated T cells and which may be used in their entirety or in part to diagnose, to stage, to treat, or to monitor the treatment of a subject with allergy, cancer, chronic graft versus host, infectious, or autoimmune disease.Type: ApplicationFiled: October 25, 2001Publication date: September 26, 2002Inventors: Christopher M. Hopkins, David P. Peterson, Benjamin G. Cocks, Phillip R. Hawkins
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Publication number: 20020132330Abstract: The invention provides a human translational regulator (TRANAC) and polynucleotides which identify and encode TRANAC. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of TRANAC.Type: ApplicationFiled: March 12, 2002Publication date: September 19, 2002Applicant: Incyte Genomics, Inc.Inventors: Jennifer L. Hillman, Phillip R. Hawkins