Patents by Inventor Piero D'Andrea

Piero D'Andrea has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of nebivolol
    Patent number: 9090922
    Abstract: The present invention relates to a novel process for the synthesis of the Nebivolol product depicted in Scheme 1, comprised of a reduced number of high-yield steps, and characterized by the enzymatic resolution of the chroman ester precursor.
    Type: Grant
    Filed: November 30, 2011
    Date of Patent: July 28, 2015
    Assignee: MENARINI INTERNATIONAL OPERATIONS LUXEMBOURG S.A.
    Inventors: Sandro Mauro, Daniela Fattori, Piero D'Andrea, Amalia Cipollone, Enzo D'Andrea, Carmela Ercolano
  • Hydroxamates as Histone Deacetylase Inhibitors and Pharmaceutical Formulations Containing Them
    Publication number: 20080207694
    Abstract: Compounds of structure (I) having histone deacetylase (HDAC) inhibitor activity are described. The compounds are chemically characterised by the presence of hydroxamic acid, with zinc as chelator, and an aromatic nucleus connected by a linker in which either a bicyclic aromatic system or a piperidino ring are present.
    Type: Application
    Filed: March 14, 2006
    Publication date: August 28, 2008
    Inventors: Cristina Rossi, Marina Porcelloni, Piero D'Andrea, Daniela Fattori, Elena Marastoni