Abstract: A flow cell for calorimetric measurements comprises a body (2) with at least one flow channel (3), which extends between an inlet opening (4) and an outlet opening (5), and a thermoelectric detector (16) for monitoring temperature changes, which occur during chemical or biochemical processes in a measuring volume (17). The measuring volume (17) is arranged in close vicinity of the outlet opening (5). The body (2) of the flow cell (1) has a good thermal conductivity of a magnitude such, that a fluid flowing through the flow channel (3) is thermostatizised prior to entering the measuring volume (17) solely by flowing through the flow channel (3) and free of any external thermostatization means. Thus, a flow cell is provided, which is capable of self-thermostatizing a fluid flowing therethrough.