Abstract: Systems and methods are provided herein for improving connections between a heart pump such a left ventricular assist device (LVAD) and the heart and/or tubing such as a graft tube. An apical connector including a cylindrical housing and a ring support connected to the housing is described. The apical connector may include a sewing ring to be connected to the patient's heart and a spring positioned within the cylindrical housing to engage a portion of the pump and secure the apical connector to the pump. Alternatively, an apical connector may include an upper and lower housing with locks positioned in channels between the housings and may include a handle and a ring to cause the locks to engage a portion of the pump. A quick connect assembly is also described for efficiently connecting a graft tube to an outlet of a heart pump using a flange with through-holes and protrusions.

Abstract: Disclosed herein is a mounting mechanism such as a drift tube mounting mechanism for mounting a drift tube provided in a drift tube accelerator vessel 10 via an elongate holding element 14. The mounting mechanism comprises a biasing mechanism comprising one or more disc spring members 46 for axially biasing the elongate holding element 14 with respect to the vessel towards a mounting position. The mounting mechanism further comprises a screw 58 having a head portion 60 and a shaft portion, said shaft portion comprising a threaded portion 64 for screwing into the elongate holding element 14. The mounting mechanism further comprises a bushing 66 comprising a sleeve portion 68 receiving at least a part of the screw shaft and separating the one or more disc spring members 46 from said screw shaft portion. The screw head portion 60 is configured to receive the axial biasing force generated by the one or more disc spring members 46.

Abstract: Disclosed herein is a mounting mechanism such as a drift tube mounting mechanism for mounting a drift tube provided in a drift tube accelerator vessel 10 via an elongate holding element 14. The mounting mechanism comprises a biasing mechanism comprising one or more disc spring members 46 for axially biasing the elongate holding element 14 with respect to the vessel towards a mounting position. The mounting mechanism further comprises a screw 58 having a head portion 60 and a shaft portion, said shaft portion comprising a threaded portion 64 for screwing into the elongate holding element 14. The mounting mechanism further comprises a bushing 66 comprising a sleeve portion 68 receiving at least a part of the screw shaft and separating the one or more disc spring members 46 from said screw shaft portion. The screw head portion 60 is configured to receive the axial biasing force generated by the one or more disc spring members 46.

Abstract: The present invention concerns a novel process for the production of known benzocycloheptathiophene derivatives of the formula: ##STR1## wherein R.sub.1 is hydrogen, chlorine, bromine or alkoxy, and R.sub.2 is alkyl. The compounds are useful as specific histaminolytics for use in the treatment of allergic conditions.

Abstract: The present invention concerns a novel process for the production of known benzocycloheptathiophene derivatives of the formula: ##SPC1##Wherein R.sub.1 is hydrogen, chlorine, bromine or alkoxy, and R.sub.2 is alkyl. The compounds are useful as specific histaminolytics for use in the treatment of allergic conditions.