Abstract: The invention relates to the 2-aminoalkyl-9-hydroxyellipticinium chloride hydrochloride of formula: ##STR1## in which Z represents hydrogen or a lower alkyl group, Alk represents a lower alkylene group and Am represents a di(lower alkyl)amino, pyrrolidino or piperidino group.These compounds are useful as antitumour agents.

Abstract: The process consists in generating a primary tube wave, in using a reflecting element for the tube wave and in recording the times of emission of the induced waves radiated by the reflecting element, in receiving and recording at least part of the induced waves, then in processing the recorded signals so as to determine the characteristics of the medium to be explored. Application in particular to exploration between boreholes.

Abstract: A measuring device for a seismic profile within a well-bore includes resilient members such as springs which are flexible in at least two directions and are interposed between a geophone and a rigid arm connected to a measuring-tool body for applying the geophone against the wall of the well-bore during each detection of seismic waves generated at the ground surface. The elasticity of the resilient members is at least equal to the elasticity of the subsurface stratum through which the well-bore extends. The resonance frequency of the mass of the geophone with the resilient members is equal at a maximum to the resonance frequency defined by the geophone mass and elasticity of the subsurface stratum.

Abstract: A method for measuring vibrational stresses and velocities of waves propagated within formations surrounding a wellbore essentially consists in simultaneously measuring the vibrational stress and vibrational velocity produced by propagation of the vibration within the medium, then in establishing a ratio of magnitudes relating to the vibrational stress and velocity in respect of one and the same measuring point. The method and device provided by the invention also find applications in the separation of different types of secondary waves generated during propagation of a primary wave in a medium.

Abstract: The present invention relates to drugs characterized in that they comprise, in association, at least one immunotoxin and at least one monovalent carboxylic ionophore.

Abstract: The present invention relates to new immunoenzymic conjugates resulting from a chemical coupling, by covalent bond, of an antibody or a fragment of antibody, which has retained the capacity of recognizing the selected antigen, with an enzyme capable of producing ammonium ions from natural substrates which are well tolerated in higher animal organisms.The invention also relates to a process for the preparation of these conjugates and the medicinal associations of said conjugates with an immunotoxin.

Abstract: The invention relates to pharmaceutical compositions comprising a combination of at least one immunotoxin and at least one mannose-containing polymer. This combination makes it possible to inhibit the rapid elimination of immunotoxins from the plasma after injection.

Abstract: Method of instantaneous acoustic logging within a wellbore.The method is characterized in that it consists of locating on drill-pipe and ground recordings elementary recordings corresponding to one and the same depth level of the drilling tool, in grouping these elementary recordings in pairs, then in intercorrelating said recordings of the pairs so as to produce in respect of each pair a correlated signal which is representative of the acoustic energy produced and of the difference in travel times of the waves received on sensors from which the pair of recordings has been obtained.A particular application is for the determination of a seismic wellbore profile.

Abstract: The present invention relates to polyfunctional hydrophilic spherical microparticles of uniform size which contain from 5 to 95% of units originating from the copolymerization of an aldehyde of the formula ##STR1## R.sub.1 being an alkyl radical, from 5 to 90% of units originating from the copolymerization of an acrylic acid ester of the formula ##STR2## in which R.sub.2 is H or alkyl and R.sub.3 is a hydroxyalkyl group, less than 15% of units originating from an acrylic acid derivative chosen from amongst ##STR3## R.sub.4, R.sub.5 and R.sub.6 being alkyl radicals, and from 0.1 to 10% of units originating from a crosslinking product.The invention also relates to a process for the preparation of the said microparticles and to the use of these microparticles for the nephelometric determination of HB.sub.s antigen.

Abstract: A method and device for making geophysical measurements in a wellbore comprising a measuring string of a plurality of measuring tools displaced along a borehole wall connected to a surface control unit by a traction system including a cable, guide pulley, connection head and junction box. The measuring tools are displaced at a relative velocity which is equal and opposite to the absolute velocity of the traction system in order to reduce the absolute velocity of the measuring tools to zero during measurement periods. The relative velocity of the tools is in the same direction as the absolute velocity of the traction system between measurement periods, with the result that the absolute velocity of the measuring tools during these periods is higher than the absolute velocity of the traction system.

Abstract: A measuring tool for producing geophysical measurements within a borehole comprises a crawler belt, at least a portion of which constitutes a support for a transducer. The crawler belt is continuously displaced within the bore hole by means of a suspension cable and guide pulley in cooperating relation with spiked shoes and retaining plates for maintaining at least the transducer-supporting portion of the crawler belt in a stationary position with respect to the borehole wall during each measurement stage.

Abstract: Imidazolides of the formula: ##STR1## in which: E represents an inert spacing structure; andG represents a group: ##STR2## or a group --S--S--X, in which X is an activating group. Application: synthesis of cytotoxic conjugates.

Abstract: The present invention relates to an anti-cancer drug, characterized in that it contains at least one product constituted by the chain A of recin conjugated by means of a disulfide bridge with at least one fraction of a monoclonal antibody of leukaemic anti-cell specificity, and to the processes for preparing the active ingredient of said drug.

Abstract: The present invention relates to cytotoxic medicines characterized in that they contain in association at least an immunotoxine and an amine or a pharmaceutically acceptable salt of said amine.

Abstract: The present invention relates to medicaments comprising, in association, at least one immunotoxin and chloroquin.

Abstract: The present invention relates to drugs useful in particular for the treatment of melanomas, characterized in that they contain an active substance which is a molecule in which the chain A of ricin is associated, by a covalent bond of disulfide type, with a human antimelanoma antibody.

Abstract: Carcinostatic products are formed by coupling, by covalent bonding, the A chain of ricin with an antibody which is capable of selectively recognizing a given antigen at the surface of cancerous cells. Such products can be made by the formation of a disulphide bridge between the free thiol group in the A chain of ricin and an immunoglobulin or immunoglobulin fragment into which a thiol group or an activated disulphide group has been introduced. The A chain of ricin and the immunoglobulin are carefully purified before use.

Abstract: Seismic exploration on land and on ocean beds is performed by emitting vibrational acoustic signals of long time-duration within a desired frequency spectrum at one or a number of points, the signals corresponding to the waves received from the reflectors being then processed. The method further consists in forming the complex spectrum of the received signal corresponding to the emitted signal in respect of each frequency band, in forming the complex spectrum of a reference of the emitted signal in respect of each frequency band and in dividing the complex spectrum of the received signal by the complex spectrum of the reference of the emitted signal, at least an external portion of each complex spectrum being eliminated in the case of each complex spectrum.