Abstract: Linker-drug compounds and antibody-drug conjugates that bind to human oncology targets are disclosed. The linker-drug compounds and antibody-drug conjugates comprise a splicing modulator drug moiety. The disclosure further relates to methods and compositions for use in the treatment of neoplastic disorders by administering the antibody-drug conjugates provided herein. In an embodiment, the splicing modulator comprises a pladienolide or a pladienolide derivative.

Abstract: A method for installing a maximum power point tracking (MPPT) controller is provided. The method includes acquiring an occlusion area proportion of a photovoltaic string in a photovoltaic system, optimizing the occlusion area proportion to generate a target occlusion area proportion, determining a target position from the photovoltaic string according to the target occlusion area proportion, and installing the MPPT controller at the target position.

Abstract: One or more implementations of the present specification provide an invoice access method and apparatus based on a blockchain, and an electronic device. The method includes: generating first ciphertext data by encrypting plaintext data of the target invoice based on a first key corresponding to an invoice issuer; generating second ciphertext data by encrypting the plaintext data of the target invoice based on a second key corresponding to an invoice receiver; adding the first ciphertext data and an user identifier of the invoice issuer to the blockchain as related to one another; and adding the second ciphertext data and an user identifier of the invoice receiver to the blockchain as related to one another.

Abstract: Methods and systems for emulating a hardware accelerator is provided. When executed by a computer, the platform includes a plurality of computational resources provided by the computer; a hardware emulator operated on a first computational resource of the plurality of computational resources; and an accelerator being emulated in the platform and operated on a second computational resource of the plurality of computational resources, the accelerator being configured to execute an offloading operation.

Abstract: The present invention discloses a flue gas low-temperature adsorption denitrification method, including: pressurizing a flue gas that has been subjected to dust removal and desulfurization, precooling the pressurized flue gas, cooling the precooled flue gas to a temperature lower than room temperature by a flue gas cooling system, flowing the flue gas at the temperature lower than room temperature into a low-temperature denitrification system, performing physical adsorption denitrification in the low-temperature denitrification system, precooling the flue gas that has been subjected to dust removal and desulfurization with the denitrificated flue gas, and flowing the heat-absorbed clean flue gas into a chimney to be discharged.

Abstract: A transcriptional regulator specifically responding to D-2-hydroxyglutarate (D-2-HG) and its application in the biological detection of D-2-HG. Wherein the transcriptional regulator is named DhdR and the nucleotide sequence is shown as SEQ ID NO: 1. The D-2-HG biosensors BD2HG-0 and BD2HG-1 are constructed using the transcriptional regulator DhdR and can detect biological samples containing D-2-HG.

Abstract: The display panel includes a plurality of light-emitting areas and a plurality of non-light-emitting areas, the plurality of light-emitting areas being space apart from each other by the plurality of non-light-emitting area; light-emitting elements each located in one of the plurality of light-emitting areas and including an anode and a cathode that are opposite to each other, and a light-emitting layer located therebetween; a cover layer covering a light-emission side of the light-emitting element. The cover layer includes a substrate and first dopants doped in the substrate, the first dopants are magnetic. When an external magnetic field intensity applied to the cover layer is changed by an amount greater than a preset magnetic field intensity, the first dopants in the substrate are rearranged from a first mode to a second mode.

Abstract: The disclosure provides a method for preparing an electrode film layer on a surface of a solar cell substrate. The method includes: a) obtaining a metal electrode material melt by heating and melting a metal electrode material under a vacuum condition; b) bombarding the metal electrode material melt with an ion source at low energy, so that it is sputtered and deposited on the surface of the solar cell substrate to form the electrode film layer; in which the energy of low energy bombarding is 30 eV to 80 eV.

Abstract: A heat pipe operating noiselessly by preventing, or reducing the effects of, the mixing of working fluid at different temperatures includes a hollow tube, a capillary structure, a working fluid, and a bushing. The porous capillary structure able to carry the fluid is disposed on an inner wall of the tube. The bushing is hollow, and the bushing is disposed on a surface of the capillary structure away from the tube. The heat pipe is divided into evaporation, adiabatic, and condensation sections, the capillary structure being at all sections. The working fluid is disposed in the capillary structure of the evaporation section, the bushing is disposed on a side of the capillary structure of the adiabatic section. The present disclosure further provides a device including the heat pipe.

Abstract: Method and system are provided for audio quality feedback during live transmission from a source that is received at multiple audience devices. The method carried out at a server includes: obtaining audio information of an audio signal as received by at least some of the audience devices in a transmission session; classifying one or more subsets of the audience devices by one or more common factors per subset; and analyzing the obtained audio information from the audience devices in conjunction with the classifications of the subsets of the audience devices to determine one or more common factors that affect received audio quality at an identified subset of the audience devices classified by the one or more common factors. The method provides feedback of the one or more common factors to at least one of the audience devices in the identified subset or to the source device, or to both.

Abstract: A heat pipe operating noiselessly by preventing, or reducing the effects of, the mixing of working fluid at different temperatures includes a hollow tube, a capillary structure, a working fluid, and a bushing. The porous capillary structure able to carry the fluid is disposed on an inner wall of the tube. The bushing is hollow, and the bushing is disposed on a surface of the capillary structure away from the tube. The heat pipe is divided into evaporation, adiabatic, and condensation sections, the capillary structure being at all sections. The working fluid is disposed in the capillary structure of the evaporation section, the bushing is disposed on a side of the capillary structure of the adiabatic section.

Abstract: The present invention relates to the field of air filtration, in particular to a polytetrafluoroethylene composite filter material and a preparation method and uses thereof. The polytetrafluoroethylene composite filter material comprises a support layer and a polytetrafluoroethylene microporous membrane layer, and the support layer and the polytetrafluoroethylene microporous membrane layer are compounded by an adhesive, wherein the adhesive comprises a two-component polyurethane adhesive, a pore forming agent and an inorganic filler.

Abstract: Provided is a method for desulphurizating and denitrating a flue gas in an integrated manner based on low-temperature adsorption. The method includes: decreasing a temperature of the flue gas below a room temperature by using a flue gas cooling system; removing moisture in the flue gas by using a dehumidification system; sending the flue gas to a SO2 and NOx adsorbing column system; and simultaneously adsorbing SO2 and NOx of the flue gas with a material of activated coke, activated carbon, a molecular sieve or diatom mud in the SO2 and NOx adsorbing column system to implement an integration of desulphurization and denitration of the flue gas based on the low-temperature adsorption. With the present method, SO2 and NOx of the flue gas can be adsorbed simultaneously in an environment having a temperature below the room temperature.

Abstract: The present invention relates to the field of air filtration, in particular to a polytetrafluoroethylene composite filter material. The polytetrafluoroethylene composite filter material comprises a supporting layer and a polytetrafluoroethylene film layer, wherein the supporting layer is a silver-plated carbon nanomaterial-modified meltblown nonwoven fabric. The polytetrafluoroethylene composite filter material is prepared by fiberizing a resin material modified by silver-plated carbon nanomaterial on the surface of a polytetrafluoroethylene film by a melt-blowing method. The polytetrafluoroethylene composite filter material of the present invention combines filtering and sterilizing functions, has higher filtering efficiency and filtering precision, has the functions of sterilizing and killing viruses, has a good isolation effect, and greatly prolongs the service life of the filter material.

Abstract: A method for desulfurizing and decarbonizing a flue gas includes: feeding a boiler flue gas after denitrating and dedusting to a water cooler; cooling the boiler flue gas in the water cooler to a temperature near room temperature, and discharging condensed water; feeding a wet flue gas to a washing tower; washing and cooling the wet flue gas with a washing liquid to separate H2O, SO2 and CO2 in a solid form from the flue gas; feeding a solid-liquid mixed slurry from a bottom of the washing tower to a solid-liquid separator to separate solid H2O, SO2 and CO2 from the washing liquid; feeding the solid H2O, SO2 and CO2 to a rectification separation column; separating CO2 from SO2 and H2O by a reboiler at a bottom of the rectification separation column; and discharging CO2, SO2 and H2O.

Abstract: Embodiments of the present disclosure relate to a method for building an application. According to the method, a request is received from a building environment to acquire at least one component for executing at least one function of at least one feature of the application. The at least one feature is to be deployed to at least one target node in a distributed service platform comprising a plurality of nodes. The at least one target node and the at least one component are determined based on the request. The at least one component is acquired from the at least one target node. The at least one component is sent to the building environment for building the at least one feature.

Abstract: A method and system for improving memory reorganization and storage technology is provided. The method includes configuring data capture settings of a database system resulting in configured data capture settings. Data objects associated with a user are retrieved and stored in a database. Overlapping data elements of the data objects are determined and associated collaboration data model software code is generated. A request for first data is received and mapped to the data objects. A clone data object associated with the first data object is generated with respect to the overlapping data elements.

Abstract: A computer-implemented method includes detecting, by a bridge container running inside a container scope, connection information about a first service instance running to provide a respective first service outside the container scope. A first virtual container is initialized inside the container scope. The first virtual container is connected to the first service instance, utilizing the connection information about the first service instance, to virtualize the first service instance inside the container scope. It is detected that that a first source container inside the container scope requires the first service of the first service instance. The first source container is connected to the first virtual container to enable the first source container to access the first service instance through the first virtual container.

Abstract: Forming an amorphous carbon layer due to lattice distortion of carbon atoms on a surface layer of a single-crystal diamond under a mechanical shear function of a hard abrasive, and generating a chemical reaction between the amorphous carbon layer on the surface layer and the reactive abrasive to achieve quickly removing carbon atoms on the surface layer of the single-crystal diamond due to a local high temperature between abrasive grains and the single-crystal diamond caused by friction at a high speed.