Patents by Inventor Piotr Bobrowicz

Piotr Bobrowicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Agonist antibodies that bind human CD137 and uses thereof
    Patent number: 11752207
    Abstract: The present disclosure relates to, inter alia, compounds (e.g., antibodies, or antigen-binding fragments thereof) that bind to an epitope of CD137 and agonize CD137, and to use of the compounds in methods for treating, or ameliorating one or more symptoms of, cancer.
    Type: Grant
    Filed: June 8, 2020
    Date of Patent: September 12, 2023
    Assignee: Compass Therapeutics LLC
    Inventors: Piotr Bobrowicz, Paul Widboom, Michael March Schmidt, Jason M. Lajoie, Robert V. Tighe, III, Cheuk Lun Leung, Ugur Eskiocak
  • ANTIGEN BINDING AGENTS THAT BIND CD277 AND USES THEREOF
    Publication number: 20210388089
    Abstract: The present disclosure relates to, inter alia, methods for treating, or ameliorating one or more symptoms of, cancer, with compounds (e.g., antibodies, or antigen-binding fragments thereof) that bind to CD277.
    Type: Application
    Filed: August 9, 2019
    Publication date: December 16, 2021
    Inventors: Michael March SCHMIDT, Brooke T. MCLAUGHLIN, Piotr BOBROWICZ, Jose R. CONEJO-GARCIA, Kyle Kristopher PAYNE
  • SURFACE DISPLAY OF WHOLE ANTIBODIES IN EUKARYOTES
    Publication number: 20210317441
    Abstract: Methods for display of recombinant whole immunoglobulins or immunoglobulin libraries on the surface of eukaryote host cells, including yeast and filamentous fungi, are described. The methods are useful for screening libraries of recombinant immunoglobulins in eukaryote host cells to identify immunoglobulins that are specific for an antigen of interest.
    Type: Application
    Filed: June 10, 2021
    Publication date: October 14, 2021
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Bianka Prinz, Natarajan Sethuraman, Dongxing Zha, Stefan Wildt, Piotr Bobrowicz
  • ANTIBODIES THAT BIND CD277 AND USES THEREOF
    Publication number: 20210309746
    Abstract: The present disclosure relates to, inter alia, compounds (e.g., antibodies, or antigen-binding fragments thereof) that bind to CD277, for treating, or ameliorating one or more symptoms of cancer.
    Type: Application
    Filed: August 9, 2019
    Publication date: October 7, 2021
    Inventors: Piotr Bobrowicz, Paul Widboom, Michael March Schmidt
  • Surface display of whole antibodies in eukaryotes
    Patent number: 11046951
    Abstract: Methods for display of recombinant whole immunoglobulins or immunoglobulin libraries on the surface of eukaryote host cells, including yeast and filamentous fungi, are described. The methods are useful for screening libraries of recombinant immunoglobulins in eukaryote host cells to identify immunoglobulins that are specific for an antigen of interest.
    Type: Grant
    Filed: October 3, 2018
    Date of Patent: June 29, 2021
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Bianka Prinz, Natarajan Sethuraman, Dongxing Zha, Stefan Wildt, Piotr Bobrowicz
  • POLYSPECIFICITY REAGENTS, METHODS FOR THEIR PREPARATION AND USE
    Publication number: 20210156872
    Abstract: The present invention relates, inter alia, to polyspecificity reagents, methods of making the same, and methods of using the same in, inter alia, the selection, screening, enrichment, and identification of non-polyspecific, and thus developable, polypeptides.
    Type: Application
    Filed: December 3, 2020
    Publication date: May 27, 2021
    Inventors: Piotr Bobrowicz, Amber D. Hanna, Jerry M. Thomas
  • Polyspecificity reagents, methods for their preparation and use
    Patent number: 10883997
    Abstract: The present invention relates, inter alia, to polyspecificity reagents, methods of making the same, and methods of using the same in, inter alia, the selection, screening, enrichment, and identification of non-polyspecific, and thus developable, polypeptides.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: January 5, 2021
    Assignee: Adimab, LLC
    Inventors: Piotr Bobrowicz, Amber D. Hanna, Jerry M. Thomas
  • AGONIST ANTIBODIES THAT BIND HUMAN CD137 AND USES THEREOF
    Publication number: 20200306374
    Abstract: The present disclosure relates to, inter alia, compounds (e.g., antibodies, or antigen-binding fragments thereof) that bind to an epitope of CD137 and agonize CD137, and to use of the compounds in methods for treating, or ameliorating one or more symptoms of, cancer.
    Type: Application
    Filed: June 8, 2020
    Publication date: October 1, 2020
    Inventors: Piotr Bobrowicz, Paul Widboom, Michael March Schmidt, Jason M. Lajoie, Robert V. Tighe, III, Cheuk Lun Leung, Ugur Eskiocak
  • Agonist antibodies that bind human CD137 and uses thereof
    Patent number: 10716851
    Abstract: The present disclosure relates to, inter alia, compounds (e.g., antibodies, or antigen-binding fragments thereof) that bind to an epitope of CD137 and agonize CD137, and to use of the compounds in methods for treating, or ameliorating one or more symptoms of, cancer.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: July 21, 2020
    Assignee: Compass Therapeutics LLC
    Inventors: Piotr Bobrowicz, Paul Widboom, Michael March Schmidt, Jason M. Lajoie, Robert V. Tighe, III, Cheuk Lun Leung, Ugur Eskiocak
  • AGONIST ANTIBODIES THAT BIND HUMAN CD137 AND USES THEREOF
    Publication number: 20200046833
    Abstract: The present disclosure relates to, inter alia, compounds (e.g., antibodies, or antigen-binding fragments thereof) that bind to an epitope of CD137 and agonize CD137, and to use of the compounds in methods for treating, or ameliorating one or more symptoms of, cancer.
    Type: Application
    Filed: October 30, 2019
    Publication date: February 13, 2020
    Inventors: Piotr BOBROWICZ, Paul WIDBOOM, Michael March SCHMIDT, Jason M. LAJOIE, Robert V. TIGHE, III, Cheuk Lun LEUNG, Ugur ESKIOCAK
  • Agonist antibodies that bind human CD137 and uses thereof
    Patent number: 10434175
    Abstract: The present disclosure relates to compounds (e.g., antibodies, or antigen-binding fragments thereof) that bind to an epitope of CD137 and agonize CD137, and to use of the compounds in methods for treating, or ameliorating one or more symptoms of, cancer.
    Type: Grant
    Filed: May 23, 2019
    Date of Patent: October 8, 2019
    Assignee: Compass Therapeutics LLC
    Inventors: Piotr Bobrowicz, Paul Widboom, Michael March Schmidt, Jason M. Lajoie, Robert V. Tighe, III, Cheuk Lun Leung, Ugur Eskiocak
  • AGONIST ANTIBODIES THAT BIND HUMAN CD137 AND USES THEREOF
    Publication number: 20190269776
    Abstract: The present disclosure relates to compounds (e.g., antibodies, or antigen-binding fragments thereof) that bind to an epitope of CD137 and agonize CD137, and to use of the compounds in methods for treating, or ameliorating one or more symptoms of, cancer.
    Type: Application
    Filed: May 23, 2019
    Publication date: September 5, 2019
    Inventors: Piotr Bobrowicz, Paul Widboom, Michael March Schmidt, Jason M. Lajoie, Robert V. Tighe, III, Cheuk Lun Leung, Ugur Eskiocak
  • AGONIST ANTIBODIES THAT BIND HUMAN CD137 AND USES THEREOF
    Publication number: 20190224315
    Abstract: The present disclosure relates to compounds (e.g., antibodies, or antigen-binding fragments thereof) that bind to an epitope of CD137 and agonize CD137, and to use of the compounds in methods for treating, or ameliorating one or more symptoms of, cancer.
    Type: Application
    Filed: April 3, 2019
    Publication date: July 25, 2019
    Inventors: Piotr Bobrowicz, Paul Widboom, Michael March Schmidt, Jason M. Lajoie, Robert V. Tighe, III, Cheuk Lun Leung, Ugur Eskiocak
  • Agonist antibodies that bind human CD137 and uses thereof
    Patent number: 10350292
    Abstract: The present disclosure relates to compounds (e.g., antibodies, or antigen-binding fragments thereof) that bind to an epitope of CD137 and agonize CD137, and to use of the compounds in methods for treating, or ameliorating one or more symptoms of, cancer.
    Type: Grant
    Filed: April 3, 2019
    Date of Patent: July 16, 2019
    Assignee: Compass Therapeutics LLC
    Inventors: Piotr Bobrowicz, Paul Widboom, Michael March Schmidt, Jason M. Lajoie, Robert V. Tighe, III, Cheuk Lun Leung, Ugur Eskiocak
  • Agonist antibodies that bind human CD137 and uses thereof
    Patent number: 10279038
    Abstract: The present disclosure relates to compounds (e.g., antibodies, or antigen-binding fragments thereof) that bind to an epitope of CD137 and agonize CD137, and to use of the compounds in methods for treating, or ameliorating one or more symptoms of, cancer.
    Type: Grant
    Filed: November 9, 2018
    Date of Patent: May 7, 2019
    Assignee: Compass Therapeutics LLC
    Inventors: Piotr Bobrowicz, Paul Widboom, Michael March Schmidt, Jason M. Lajoie, Robert V. Tighe, III, Cheuk Lun Leung, Ugur Eskiocak
  • Agonist antibodies that bind human CD137 and uses thereof
    Patent number: 10279039
    Abstract: The present disclosure relates to compounds (e.g., antibodies, or antigen-binding fragments thereof) that bind to an epitope of CD137 and agonize CD137, and to use of the compounds in methods for treating, or ameliorating one or more symptoms of, cancer.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: May 7, 2019
    Assignee: Compass Therapeutics LLC
    Inventors: Piotr Bobrowicz, Paul Widboom, Michael March Schmidt, Jason M. Lajoie, Robert V. Tighe, III, Cheuk Lun Leung, Ugur Eskiocak
  • Agonist antibodies that bind human CD137 and uses thereof
    Patent number: 10279040
    Abstract: The present disclosure relates to compounds (e.g., antibodies, or antigen-binding fragments thereof) that bind to an epitope of CD137 and agonize CD137, and to use of the compounds in methods for treating, or ameliorating one or more symptoms of, cancer.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: May 7, 2019
    Assignee: Compass Therapeutics LLC
    Inventors: Piotr Bobrowicz, Paul Widboom, Michael March Schmidt, Jason M. Lajoie, Robert V. Tighe, III, Cheuk Lun Leung, Ugur Eskiocak
  • AGONIST ANTIBODIES THAT BIND HUMAN CD137 AND USES THEREOF
    Publication number: 20190125866
    Abstract: The present disclosure relates to compounds (e.g., antibodies, or antigen-binding fragments thereof) that bind to an epitope of CD137 and agonize CD137, and to use of the compounds in methods for treating, or ameliorating one or more symptoms of, cancer.
    Type: Application
    Filed: December 21, 2018
    Publication date: May 2, 2019
    Inventors: Piotr BOBROWICZ, Paul WIDBOOM, Michael March SCHMIDT, Jason M. LAJOIE, Robert V. TIGHE, III, Cheuk Lun LEUNG, Ugur ESKIOCAK
  • AGONIST ANTIBODIES THAT BIND HUMAN CD137 AND USES THEREOF
    Publication number: 20190099488
    Abstract: The present disclosure relates to compounds (e.g., antibodies, or antigen-binding fragments thereof) that bind to an epitope of CD137 and agonize CD137, and to use of the compounds in methods for treating, or ameliorating one or more symptoms of, cancer.
    Type: Application
    Filed: December 13, 2018
    Publication date: April 4, 2019
    Inventors: Piotr Bobrowicz, Paul Widboom, Michael March Schmidt, Jason M. Lajoie, Robert V. Tighe, III, Cheuk Lun Leung, Ugur Eskiocak
  • POLYSPECIFICITY REAGENTS, METHODS FOR THEIR PREPARATION AND USE
    Publication number: 20190079098
    Abstract: The present invention relates, inter alia, to polyspecificity reagents, methods of making the same, and methods of using the same in, inter alia, the selection, screening, enrichment, and identification of non-polyspecific, and thus developable, polypeptides.
    Type: Application
    Filed: November 20, 2018
    Publication date: March 14, 2019
    Inventors: Piotr Bobrowicz, Amber D. Hanna, Jerry M. Thomas