Patents by Inventor Pol-Henri W. Guivarc'h

Pol-Henri W. Guivarc'h has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Spray drying process and compositions of fenofibrate
    Patent number: 6696084
    Abstract: The present invention relates to a novel spray drying process for the preparation of pharmaceutical compositions containing small particles of phospholipid-stabilized fenofibrate. This invention also relates to spray dried powdered compositions prepared according to this process, and to dosage forms of fenofibrate (capsules, tablets, powders, granules, and dispersions) prepared from these powdered compositions. The powdered compositions and dosage forms are useful in the treatment of dyslipidemia and dyslipoproteinemia and have the advantage that they provide reduced in vivo variability in the bioavailability of fenofibrate active species among fed and fasted patients when administered orally.
    Type: Grant
    Filed: April 20, 2001
    Date of Patent: February 24, 2004
    Assignee: RTP Pharma Inc.
    Inventors: Gary W. Pace, Awadesh K. Mishra, Robert A. Snow, Indu Parikh, Pol-Henri W. Guivarc'h
  • Fibrate-statin combinations with reduced fed-fasted effects
    Patent number: 6534088
    Abstract: This invention discloses an orally administered pharmaceutical composition for the treatment of elevated levels of cholesterol and related conditions comprising a statin and fenofibrate in the form of microparticles of solid fenofibrate that are stabilized by phospholipid as a surface active substance, wherein a therapeutically effective amount of the composition provides the statin and a quantity of fenofibrate to a fasted human patient that is greater than 80% of the quantity of fenofibrate provided by the same amount of the composition when administered to the same patient who has been fed a high fat meal.
    Type: Grant
    Filed: April 20, 2001
    Date of Patent: March 18, 2003
    Assignee: SkyePharma Canada Inc.
    Inventors: Pol-Henri W. Guivarc'h, Indu Parikh, Robert A. Snow
  • Fibrate-statin combinations with reduced fed-fasted effects
    Publication number: 20020161032
    Abstract: This invention discloses an orally administered pharmaceutical composition for the treatment of elevated levels of cholesterol and related conditions comprising a statin and fenofibrate in the form of microparticles of solid fenofibrate that are stabilized by phospholipid as a surface active substance, wherein a therapeutically effective amount of the composition provides the statin and a quantity of fenofibrate to a fasted human patient that is greater than 80% of the quantity of fenofibrate provided by the same amount of the composition when administered to the same patient who has been fed a high fat meal.
    Type: Application
    Filed: April 20, 2001
    Publication date: October 31, 2002
    Inventors: Pol-Henri W. Guivarc'h, Indu Parikh, Robert A. Snow
  • Spray drying process and compositions of fenofibrate
    Publication number: 20020056206
    Abstract: The present invention relates to a novel spray drying process for the preparation of pharmaceutical compositions containing small particles of phospholipid-stabilized fenofibrate. This invention also relates to spray dried powdered compositions prepared according to this process, and to dosage forms of fenofibrate (capsules, tablets, powders, granules, and dispersions) prepared from these powdered compositions. The powdered compositions and dosage forms are useful in the treatment of dyslipidemia and dyslipoproteinemia and have the advantage that they provide reduced in vivo variability in the bioavailability of fenofibrate active species among fed and fasted patients when administered orally.
    Type: Application
    Filed: April 20, 2001
    Publication date: May 16, 2002
    Inventors: Gary W. Pace, Awadesh K. Mishra, Robert A. Snow, Indu Parikh, Pol-Henri W. Guivarc'h