Patents by Inventor Poon Lit Man

Poon Lit Man has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR DETECTING DNA ORIGINATING FROM DIFFERENT INDIVIDUALS
    Publication number: 20120190029
    Abstract: In a first aspect, the present invention features methods for differentiating DNA species originating from different individuals in a biological sample. These methods may be used to differentiate or detect fetal DNA in a maternal sample or to differentiate DNA of an organ donor from DNA of an organ recipient. In preferred embodiments, the DNA species are differentiated by observing epigenetic differences in the DNA species such as differences in DNA methylation. In a second aspect, the present invention features methods of detecting genetic abnormalities in a fetus by detecting fetal DNA in a biological sample obtained from a mother. In a third aspect, the present invention features methods for differentiating DNA species originating from an organ donor from those of an organ recipient. In a fourth aspect, the present invention features kits for differentiating DNA species originating from different individuals in a biological sample.
    Type: Application
    Filed: April 2, 2012
    Publication date: July 26, 2012
    Applicant: The Chinese University of Hong Kong
    Inventors: Lo Yuk Ming Dennis, Poon Lit Man
  • Non-invasive methods for detecting non-host DNA in a host using epigenetic differences between the host and non-host DNA
    Patent number: 6927028
    Abstract: In a first aspect, the present invention features methods for differentiating DNA species originating from different individuals in a biological sample. These methods may be used to differentiate or detect fetal DNA in a maternal sample or to differentiate DNA of an organ donor from DNA of an organ recipient. In preferred embodiments, the DNA species are differentiated by observing epigenetic differences in the DNA species such as differences in DNA methylation. In a second aspect, the present invention features methods of detecting genetic abnormalities in a fetus by detecting fetal DNA in a biological sample obtained from a mother. In a third aspect, the present invention features methods for differentiating DNA species originating from an organ donor from those of an organ recipient. In a fourth aspect, the present invention features kits for differentiating DNA species originating from different individuals in a biological sample.
    Type: Grant
    Filed: August 31, 2001
    Date of Patent: August 9, 2005
    Assignee: Chinese University of Hong Kong
    Inventors: Lo Yuk Ming Dennis, Poon Lit Man
  • Methods for detecting DNA originating from different individuals
    Publication number: 20030044388
    Abstract: In a first aspect, the present invention features methods for differentiating DNA species originating from different individuals in a biological sample. These methods may be used to differentiate or detect fetal DNA in a maternal sample or to differentiate DNA of an organ donor from DNA of an organ recipient. In preferred embodiments, the DNA species are differentiated by observing epigenetic differences in the DNA species such as differences in DNA methylation. In a second aspect, the present invention features methods of detecting genetic abnormalities in a fetus by detecting fetal DNA in a biological sample obtained from a mother. In a third aspect, the present invention features methods for differentiating DNA species originating from an organ donor from those of an organ recipient. In a fourth aspect, the present invention features kits for differentiating DNA species originating from different individuals in a biological sample.
    Type: Application
    Filed: August 31, 2001
    Publication date: March 6, 2003
    Applicant: The Chinese University of Hong Kong
    Inventors: Lo Yuk Ming Dennis, Poon Lit Man