Patents by Inventor Poonam Agarwal
Poonam Agarwal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20180355441Abstract: The present invention relates to a new compound for visualizing DNA-platinum crosslink, and its use as a research tool and in screening method for identifying candidate drug to be used in combination with platinating compounds such as cisplatin, carboplatin, and oxaliplatin. The project leading to this application has received funding from the European Research Council (ERC) under the European Union's Horizon 2020 research and innovation program (grant agreement No [647973]).Type: ApplicationFiled: December 15, 2016Publication date: December 13, 2018Inventors: RAPHAEL RODRIGUEZ, EMMANOUIL ZACHARIOUDAKIS, LAVANIYA KUNALINGAM, ALEXANDRA BARTOLI, KYLE MILLER, POONAM AGARWAL
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Patent number: 8765418Abstract: The present invention provides compositions and methods for the detection and characterization of HPV sequences. More particularly, the present invention provides compositions, methods and kits for using invasive cleavage structure assays (e.g. the INVADER assay) to screen nucleic acid samples, e.g., from patients, for the presence of any one of a collection of HPV sequences. The present invention also provides compositions, methods and kits for screening sets of HPV sequences in a single reaction container.Type: GrantFiled: February 15, 2013Date of Patent: July 1, 2014Assignee: Third Wave Technologies, Inc.Inventors: Angela Hudson, Tamara Sander, Poonam Agarwal, Michelle Garsha, Hon Ip, Robert W. Kwiatkowski, Vecheslav Elagin, Marilyn Olson-Munoz, Michelle Curtis, Sarah Olson, Ilse Tyler
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Publication number: 20130149697Abstract: The present invention provides compositions and methods for the detection and characterization of HPV sequences. More particularly, the present invention provides compositions, methods and kits for using invasive cleavage structure assays (e.g. the INVADER assay) to screen nucleic acid samples, e.g., from patients, for the presence of any one of a collection of HPV sequences. The present invention also provides compositions, methods and kits for screening sets of HPV sequences in a single reaction container.Type: ApplicationFiled: February 15, 2013Publication date: June 13, 2013Inventors: Angela Hudson, Tamara Sander, Poonam Agarwal, Michelle Garsha, Hon Ip, Robert W. Kwiatkowski, JR., Vecheslav Elagin, Marilyn Olson-Munoz, Michelle Curtis, Sarah Olson, Ilse Tyler
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Patent number: 8389245Abstract: The present invention provides compositions and methods for the detection and characterization of HPV sequences. More particularly, the present invention provides compositions, methods and kits for using invasive cleavage structure assays (e.g. the INVADER assay) to screen nucleic acid samples, e.g., from patients, for the presence of any one of a collection of HPV sequences. The present invention also provides compositions, methods and kits for screening sets of HPV sequences in a single reaction container.Type: GrantFiled: September 19, 2007Date of Patent: March 5, 2013Assignee: Third Wave Technologies, Inc.Inventors: Angela Hudson, Tamara Sander, Poonam Agarwal, Michelle Garsha, Hon Ip, Robert W. Kwiatkowski, Jr., Vecheslav Elagin, Marilyn Olson-Munoz, Michelle Curtis, Sarah Olson, Ilse Tyler
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Patent number: 7932039Abstract: The present invention provides methods, compositions, and kits for detecting the presence or absence of target sequences in a sample, where the sample also contains interfering sequences that are similar or identical to the target sequences. In particular, the present invention provides blocker oligonucleotides that at least partially inhibit the formation of invasive cleavage structures with the interfering sequences but do not substantially inhibit the formation of invasive cleavage structures with the target sequences.Type: GrantFiled: January 27, 2009Date of Patent: April 26, 2011Assignee: Third Wave Technologies, Inc.Inventors: Poonam Agarwal, Robert W. Kwiatkowski, Jr.
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Publication number: 20090203018Abstract: The present invention provides methods, compositions, and kits for detecting the presence or absence of target sequences in a sample, where the sample also contains interfering sequences that are similar or identical to the target sequences. In particular, the present invention provides blocker oligonucleotides that at least partially inhibit the formation of invasive cleavage structures with the interfering sequences but do not substantially inhibit the formation of invasive cleavage structures with the target sequences.Type: ApplicationFiled: January 27, 2009Publication date: August 13, 2009Applicant: THIRD WAVE TECHNOLOGIES, INC.Inventors: Poonam Agarwal, Robert W. Kwiatkowski, JR.
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Patent number: 7527948Abstract: The present invention provides compositions and methods for the detection and characterization of HPV sequences. More particularly, the present invention provides compositions, methods and kits for using invasive cleavage structure assays (e.g. the INVADER assay) to screen nucleic acid samples, e.g., from patients, for the presence of any one of a collection of HPV sequences. The present invention also provides compositions, methods and kits for screening sets of HPV sequences in a single reaction container.Type: GrantFiled: September 27, 2004Date of Patent: May 5, 2009Assignee: Third Wave Technologies, Inc.Inventors: Angela Hudson, Tamara Sander, Poonam Agarwal, Michelle Garsha, Hon Ip, Robert W. Kwiatkowski, Jr., Vecheslav Elagin, Marilyn Olson-Munoz, Michelle Curtis, Sarah Olson, Ilse Tyler
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Patent number: 7482127Abstract: The present invention provides methods, compositions, and kits for detecting the presence or absence of target sequences in a sample, where the sample also contains interfering sequences that are similar or identical to the target sequences. In particular, the present invention provides blocker oligonucleotides that at least partially inhibit the formation of invasive cleavage structures with the interfering sequences but do not substantially inhibit the formation of invasive cleavage structures with the target sequences.Type: GrantFiled: November 3, 2006Date of Patent: January 27, 2009Assignee: Third Wave Technologies, Inc.Inventors: Poonam Agarwal, Robert W. Kwiatowski, Jr.
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Publication number: 20080176215Abstract: The present invention provides compositions and methods for the detection and characterization of HPV sequences. More particularly, the present invention provides compositions, methods and kits for using invasive cleavage structure assays (e.g. the INVADER assay) to screen nucleic acid samples, e.g., from patients, for the presence of any one of a collection of HPV sequences. The present invention also provides compositions, methods and kits for screening sets of HPV sequences in a single reaction container.Type: ApplicationFiled: September 19, 2007Publication date: July 24, 2008Applicant: Third Wave Technologies, Inc.Inventors: Angela Hudson, Tamara Sander, Poonam Agarwal, Michelle Garsha, Hon Ip, Robert W. Kwiatkowski, Vecheslav Elagin, Marilyn Olson-Munoz, Michelle Curtis, Sarah Olson, Ilse Tyler
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Publication number: 20070202517Abstract: The present invention provides methods, compositions, and kits for detecting the presence or absence of target sequences in a sample, where the sample also contains interfering sequences that are similar or identical to the target sequences. In particular, the present invention provides blocker oligonucleotides that at least partially inhibit the formation of invasive cleavage structures with the interfering sequences but do not substantially inhibit the formation of invasive cleavage structures with the target sequences.Type: ApplicationFiled: November 3, 2006Publication date: August 30, 2007Applicant: Third Wave Technologies, Inc.Inventors: Poonam Agarwal, Robert Kwiatkowski
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Publication number: 20070111200Abstract: The present invention provides compositions and methods for the detection and characterization of HPV sequences. More particularly, the present invention provides compositions, methods and kits for using invasive cleavage structure assays (e.g. the INVADER assay) to screen nucleic acid samples, e.g., from patients, for the presence of any one of a collection of HPV sequences. The present invention also provides compositions, methods and kits for screening sets of HPV sequences in a single reaction container.Type: ApplicationFiled: September 27, 2004Publication date: May 17, 2007Inventors: Angela Hudson, Tamara Sander, Poonam Agarwal, Michelle Garsha, Hon Ip, Robert Kwiatkowski, Vecheslav Elagin, Marilyn Olson-Munoz, Michelle Curtis, Sarah Olson, Ilse Tyler
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Publication number: 20060147938Abstract: The present invention provides compositions and methods for the detection and characterization of mutations associated with cystic fibrosis. More particularly, the present invention provides compositions, methods and kits for using invasive cleavage structure assays (e.g. the INVADER assay) to screen nucleic acid samples, e.g., from patients, for the presence of any one of a collection of mutations in the CFTR gene associated with cystic fibrosis. The present invention also provides compositions, methods and kits for screening sets of CFTR alleles in a single reaction container.Type: ApplicationFiled: November 14, 2003Publication date: July 6, 2006Applicant: Third Wave Technologies, Inc.Inventors: Molly Accola, Susan Wigdal, Andrea Mast, Christian Bartholomay, Robert Kwiatkowski, Vincent Tevere, Hon Ip, Kathleen Carroll, Patrick Peterson, Poonam Agarwal, Nancy Jarvis, Jeff Hall, Robert Roeven
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Patent number: 6913881Abstract: The present invention relates to compositions and methods for the detection and characterization of nucleic acid sequences and variations in nucleic acid sequences. The present invention relates to methods for forming a nucleic acid cleavage structure on a target sequence and cleaving the nucleic acid cleavage structure in a site-specific manner. For example, in some embodiments, a 5? nuclease activity from any of a variety of enzymes is used to cleave the target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.Type: GrantFiled: November 15, 2000Date of Patent: July 5, 2005Assignee: Third Wave Technologies, Inc.Inventors: Brian D. Aizenstein, Eric B. Rasmussen, Jeff G. Hall, Poonam Agarwal, David Arco, Myrta W. Atiles, Deborah E. Burris, Monika de Arruda Indig, Scott M. Law, Andrea L. Mast, David J. Marshall, Carolyn W. Miller, Mary C. Oldenberg, James R. Prudent, Jennifer M. Schneiders, Mary Ann Brow, Victor Lyamichev