Patents by Inventor Pradnya NARKHEDE

Pradnya NARKHEDE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR HIGHLY SENSITIVE DNA METHYLATION ANALYSIS
    Publication number: 20220033890
    Abstract: Methods, compositions and kits are provided to amplify the amount of genomic methylated DNA can by subsequently analyzed and/or sequenced. It has particular use with small amounts of DNA, including, but not limited to cell free DNA samples. In some embodiments, the ratio of polymerase and methyltransferase is controlled in order to provide maximum yields. In some embodiments, a dual primase/polymerase is used.
    Type: Application
    Filed: September 27, 2021
    Publication date: February 3, 2022
    Applicant: The University of Chicago
    Inventors: Chuan HE, Boxuan Simen ZHAO, Pradnya NARKHEDE, Chang LIU, Xiaolong CUI
  • Method for highly sensitive DNA methylation analysis
    Patent number: 11130991
    Abstract: Methods, compositions and kits are provided to amplify the amount of genomic methylated DNA can by subsequently analyzed and/or sequenced. It has particular use with small amounts of DNA, including, but not limited to cell free DNA samples. In some embodiments, the ratio of polymerase and methyltransferase is controlled in order to provide maximum yields. In some embodiments, a dual primase/polymerase is used.
    Type: Grant
    Filed: March 8, 2018
    Date of Patent: September 28, 2021
    Assignee: THE UNIVERSITY OF CHICAGO
    Inventors: Chuan He, Boxuan Simen Zhao, Pradnya Narkhede, Chang Liu, Xiaolong Cui
  • METHOD FOR HIGHLY SENSITIVE DNA METHYLATION ANALYSIS
    Publication number: 20200032330
    Abstract: Methods, compositions and kits are provided to amplify the amount of genomic methylated DNA can by subsequently analyzed and/or sequenced. It has particular use with small amounts of DNA, including, but not limited to cell free DNA samples. In some embodiments, the ratio of polymerase and methyltransferase is controlled in order to provide maximum yields. In some embodiments, a dual primase/polymerase is used.
    Type: Application
    Filed: March 8, 2018
    Publication date: January 30, 2020
    Inventors: Chuan HE, Boxuan Simen ZHAO, Pradnya NARKHEDE, Chang LIU, Xiaolong CUI