Patents by Inventor Prakash Narayan

Prakash Narayan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20180009793
    Abstract: The present invention provides compositions and formulations of compounds having formula (I) and pharmaceutically acceptable derivatives thereof, wherein p, R1, R2 and B are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of any of a number of injuries, conditions or diseases in which HGF/SF or the activities thereof, or agonists or antagonists thereof have a therapeutically useful role. In addition, methods are provided for treating such diseases or diseases starting at a time after the onset of the injury, condition or disease.
    Type: Application
    Filed: February 23, 2017
    Publication date: January 11, 2018
    Inventors: Weizhong Cai, Prakash Narayan, Bijoy Panicker, David E. Smith
  • Publication number: 20170334736
    Abstract: Embodiments described generally relate to systems comprising a humidifier (e.g., a bubble column humidifier) and a heating device (e.g. a heat exchanger), and associated methods. In certain embodiments, the heating device heats a first liquid stream comprising a condensable fluid in liquid phase (e.g., water) and a dissolved salt (e.g., NaCl) to a relatively low temperature (e.g., about 90° C. or less) prior to the first liquid stream entering the humidifier through a main humidifier liquid inlet. In some cases, the system comprising the humidifier and the heating device requires only low-grade heat to operate, which may be advantageous due to the low cost and high availability of such heat.
    Type: Application
    Filed: May 20, 2016
    Publication date: November 23, 2017
    Applicant: Gradiant Corporation
    Inventors: Steven Lam, Conor Thomas Wilson, Maximus G. St. John, Prakash Narayan Govindan
  • Publication number: 20170334737
    Abstract: Embodiments described herein generally relate to humidification-dehumidification desalination systems, including apparatuses that include a vessel comprising a humidification region (e.g., a bubble column humidification region) and a dehumidification region (e.g., a bubble column dehumidification region), mobile humidification-dehumidification (HDH) desalination systems (e.g., systems having a relatively low height and/or a relatively small footprint), and associated systems and methods. Certain embodiments generally relate to methods of operating, controlling, and/or cleaning desalination systems comprising a plurality of desalination units (e.g., HDH desalination units).
    Type: Application
    Filed: May 19, 2017
    Publication date: November 23, 2017
    Applicant: Gradiant Corporation
    Inventors: Prakash Narayan Govindan, Maximus G. St. John, Steven Lam
  • Patent number: 9790102
    Abstract: A feed liquid flows into a second-stage humidifier chamber to form a second-stage humidifier bath. A first remnant of the feed liquid from the second-stage humidifier chamber then flows into a first-stage humidifier chamber to form a first-stage humidifier bath having a temperature lower than that of the second-stage bath. A second remnant of the feed liquid is then removed from the first-stage humidifier. Meanwhile, a carrier gas is injected into and bubbled through the first-stage humidifier bath, collecting a vaporizable component in vapor form from the first remnant of the feed liquid to partially humidify the carrier gas. The partially humidified carrier gas is then bubbled through the second-stage humidifier bath, where the carrier gas collects more of the vaporizable component in vapor form from the feed liquid to further humidify the carrier gas before the humidified carrier gas is removed from the second-stage humidifier chamber.
    Type: Grant
    Filed: August 31, 2015
    Date of Patent: October 17, 2017
    Assignees: Massachusetts Institute of Technology, King Fahd University of Petroleum and Minerals
    Inventors: Prakash Narayan Govindan, Mostafa H. Elsharqawy, Steven Lam, Maximus G. St. John, John H. Lienhard
  • Publication number: 20170203977
    Abstract: Systems and methods related to desalination systems are described herein. According to some embodiments, the desalination systems are transiently operated and/or configured to facilitate transient operation. In some embodiments, a liquid stream comprising water and at least one dissolved salt is circulated through a fluidic circuit comprising a desalination system. In some embodiments, a portion of the desalination system (e.g., a humidifier) is configured to remove at least a portion of the water from the liquid stream to produce a concentrated brine stream enriched in the dissolved salt. In certain cases, the concentrated brine stream is recirculated through the fluidic circuit until the concentrated brine stream reaches a relatively high density (e.g., at least about 10 pounds per gallon) and/or a relatively high salinity (e.g., a total dissolved salt concentration of at least about 25 wt %).
    Type: Application
    Filed: March 21, 2017
    Publication date: July 20, 2017
    Applicant: Gradiant Corporation
    Inventors: Prakash Narayan Govindan, Maximus G. St. John, Steven Lam, Mark Zaloudek, Karim M. Chehayeb, Samar Shah
  • Patent number: 9700811
    Abstract: Condensing apparatuses and their use in various heat and mass exchange systems are generally described. The condensing apparatuses, such as bubble column condensers, may employ a heat exchanger positioned external to the condensing vessel to remove heat from a bubble column condenser outlet stream to produce a heat exchanger outlet stream. In certain cases, the condensing apparatus may also include a cooling device positioned external to the vessel configured and positioned to remove heat from the heat exchanger outlet stream to produce a cooling device outlet stream. The condensing apparatus may be configured to include various internal features, such as a vapor distribution region and/or a plurality of liquid flow control weirs and/or chambers within the apparatus having an aspect ratio of at least 1.5. A condensing apparatus may be coupled with a humidifier to form part of a desalination system, in certain cases.
    Type: Grant
    Filed: March 24, 2015
    Date of Patent: July 11, 2017
    Assignee: Gradiant Corporation
    Inventors: Prakash Narayan Govindan, Steven Lam, Maximus G. St. John
  • Publication number: 20170195386
    Abstract: The invention is based, in part, on a system for allowing at least one client to real-time monitor and, or playback at least one real-world recognized event via at least one processor-controlled video camera, said system comprising: a processor; a non-transitory storage medium coupled to the processor; encoded instructions stored in the non-transitory storage medium, which when executed by the processor, cause the processor to: detect a threshold-grade event from audio-video data of a real-world environment captured from a processor-controlled video camera by an event detection module within an event management system applying event detection parameters; analyze the threshold-grade event for categorization into any one of a recognized event by an event recognition module within the event management system applying event recognition parameters; transmit at least any one of a single stream of the recognized event and, or a single stream of a audio-video sequence succeeding and, or preceding the recognized event
    Type: Application
    Filed: March 20, 2017
    Publication date: July 6, 2017
    Inventors: Vaidhi Nathan, Krishna Khadloya, Albert Kay, Prakash Narayan
  • Publication number: 20170174543
    Abstract: Cations that can precipitate from an aqueous composition to produce scaling are sequestered by adding a multi-dentate ligand to the aqueous composition. The multi-dentate ligand bonds with the cation to form a non-scaling ionic complex; and the aqueous solution with the ionic complex is used in a process that produces substantially pure water from the aqueous composition, where the cation, absent formation of the ionic complex, is subject to scaling. The pH of the aqueous composition (or a brine including components of the aqueous composition) is then reduced to release the cation from the multi-dentate ligand; and the multi-dentate ligand, after the cation is released, is then reused in a predominantly closed loop.
    Type: Application
    Filed: March 2, 2017
    Publication date: June 22, 2017
    Applicant: Massachusetts Institute of Technology
    Inventors: Prakash Narayan Govindan, Windsor Sung, Steven Lam, Maximus G. St. John, John H. Lienhard, Mohammed Mirhi, Anurag Bajpayee
  • Publication number: 20170152156
    Abstract: A carrier gas is directed through a humidification chamber in a humidifier, where the carrier gas flow is directly contacted with a feed liquid to humidify the carrier gas with water evaporated from the feed liquid, producing a humidified gas flow. The humidified gas flow is then compressed in a compressor and then directed through a dehumidification chamber in a dehumidifier, where the compressed humidified gas flow is dehumidified to condense water from the compressed humidified gas flow. The dehumidified gas flow is then expanded in an expander, wherein the expansion of the dehumidified gas flow generates motion (e.g., rotation of a shaft), and wherein the motion generated in the expander is transferred to the compressor, where the motion compresses the humidified gas flow. Heat is also removed from the expanded dehumidified gas flow and transferred to compressed dehumidified gas flow upstream from the expander.
    Type: Application
    Filed: June 29, 2015
    Publication date: June 1, 2017
    Applicants: Massachusetts Institute of Technology, King Fahd University of Petroleum & Minerals
    Inventors: Amro Al-Qutub, Prakash Narayan Govindan, John H. Lienhard
  • Publication number: 20170144906
    Abstract: Described herein are systems and methods for treating an aqueous input stream comprising at least one suspended and/or emulsified immiscible phase (e.g., oil, grease) and, in some cases, one or more additional contaminants, such as solubilized bicarbonate (HCO3?) ions, solubilized divalent cations (e.g., Ca2+, Mg2+), solubilized trivalent cations (e.g., Fe3+, Al3+), organic material (e.g., humic acid, fulvic acid), hydrogen sulfide (H2S), and/or suspended solids. According to certain embodiments, the aqueous feed stream is supplied to a water treatment system comprising a chemical coagulation apparatus and a suspended solids removal apparatus (e.g., a clarifier). Within the chemical coagulation apparatus, an amount of an inorganic coagulant (e.g., aluminum chlorohydrate, polyaluminum chloride), an amount of a strong base (e.g., sodium hydroxide), and an amount of a polyelectrolyte (e.g., polyacrylamide) may be added to the aqueous input stream to form a chemically-treated stream.
    Type: Application
    Filed: November 30, 2016
    Publication date: May 25, 2017
    Applicant: Gradiant Corporation
    Inventors: Jonn-Ross Andrews, Prakash Narayan Govindan, Maximus G. St. John, Steven Lam
  • Publication number: 20170113947
    Abstract: A counter-flow simultaneous heat and mass exchange device is operated by directing flows of two fluids into a heat and mass exchange device at initial mass flow rates where ideal changes in total enthalpy rates of the two fluids are unequal. At least one of the following state variables in the fluids is measured: temperature, pressure and concentration, which together define the thermodynamic state of the two fluid streams at the points of entry to and exit from the device. The flow rates of the fluids at the points of entry and/or exit to/from the device are measured; and the mass flow rate of at least one of the two fluids is changed such that the ideal change in total enthalpy rates of the two fluids through the device are brought closer to being equal.
    Type: Application
    Filed: January 9, 2017
    Publication date: April 27, 2017
    Applicant: Gradiant Corporation
    Inventors: Prakash Narayan Govindan, Maximus G. St. John, Karim M. Chehayeb, Steven Lam
  • Patent number: 9617169
    Abstract: Systems and methods related to desalination systems are described herein. According to some embodiments, the desalination systems are transiently operated and/or configured to facilitate transient operation. In some embodiments, a liquid stream comprising water and at least one dissolved salt is circulated through a fluidic circuit comprising a desalination system. In some embodiments, a portion of the desalination system (e.g., a humidifier) is configured to remove at least a portion of the water from the liquid stream to produce a concentrated brine stream enriched in the dissolved salt. In certain cases, the concentrated brine stream is recirculated through the fluidic circuit until the concentrated brine stream reaches a relatively high density (e.g., at least about 10 pounds per gallon) and/or a relatively high salinity (e.g., a total dissolved salt concentration of at least about 25 wt %).
    Type: Grant
    Filed: January 11, 2016
    Date of Patent: April 11, 2017
    Assignee: Gradiant Corporation
    Inventors: Prakash Narayan Govindan, Maximus G. St. John, Steven Lam, Mark Zaloudek, Karim M. Chehayeb, Samar Shah
  • Patent number: 9617179
    Abstract: Cations that can precipitate from an aqueous composition to produce scaling are sequestered by adding a multi-dentate ligand to the aqueous composition. The multi-dentate ligand bonds with the cation to form a non-scaling ionic complex; and the aqueous solution with the ionic complex is used in a process that produces substantially pure water from the aqueous composition, where the cation, absent formation of the ionic complex, is subject to scaling. The pH of the aqueous composition (or a brine including components of the aqueous composition) is then reduced to release the cation from the multi-dentate ligand; and the multi-dentate ligand, after the cation is released, is then reused in a predominantly closed loop.
    Type: Grant
    Filed: August 5, 2013
    Date of Patent: April 11, 2017
    Assignee: Massachusetts Institute of Technology
    Inventors: Prakash Narayan Govindan, Windsor Sung, Steven Lam, Maximus G. St. John, John H. Lienhard, V, Mohammed Mirhi, Anurag Bajpayee
  • Patent number: 9579590
    Abstract: A counter-flow simultaneous heat and mass exchange device is operated by directing flows of two fluids into a heat and mass exchange device at initial mass flow rates where ideal changes in total enthalpy rates of the two fluids are unequal. At least one of the following state variables in the fluids is measured: temperature, pressure and concentration, which together define the thermodynamic state of the two fluid streams at the points of entry to and exit from the device. The flow rates of the fluids at the points of entry and/or exit to/from the device are measured; and the mass flow rate of at least one of the two fluids is changed such that the ideal change in total enthalpy rates of the two fluids through the device are brought closer to being equal.
    Type: Grant
    Filed: December 18, 2014
    Date of Patent: February 28, 2017
    Assignee: Gradiant Corporation
    Inventors: Prakash Narayan Govindan, Maximus G. St. John, Karim M. Chehayeb, Steven Lam
  • Patent number: 9556041
    Abstract: Selective scaling in water treatment systems in which desalination is performed is generally described. According to certain embodiments, the location of the formation of solid scale within a water treatment system is controlled by adjusting one or more system parameters, such as the temperature and/or flow velocity of a saline stream within the water treatment system.
    Type: Grant
    Filed: November 19, 2015
    Date of Patent: January 31, 2017
    Assignee: Gradiant Corporation
    Inventors: Prakash Narayan Govindan, Steven Lam, Maximus G. St. John, Jonn-Ross Andrews
  • Publication number: 20160375375
    Abstract: Embodiments described herein generally relate to humidification-dehumidification desalination systems, including apparatuses that include a vessel comprising a humidification region (e.g., a bubble column humidification region) and a dehumidification region (e.g., a bubble column dehumidification region), mobile humidification-dehumidification (HDH) desalination systems (e.g., systems having a relatively low height and/or a relatively small footprint), and associated systems and methods. Certain embodiments generally relate to methods of operating, controlling, and/or cleaning desalination systems comprising a plurality of desalination units (e.g., HDH desalination units).
    Type: Application
    Filed: May 20, 2016
    Publication date: December 29, 2016
    Applicant: Gradiant Corporation
    Inventors: Prakash Narayan Govindan, Maximus G. St. John, Steven Lam
  • Publication number: 20160340208
    Abstract: Systems and methods related to desalination systems are described herein. According to some embodiments, the desalination systems are transiently operated and/or configured to facilitate transient operation. In some embodiments, a liquid stream comprising water and at least one dissolved salt is circulated through a fluidic circuit comprising a desalination system. In some embodiments, a portion of the desalination system (e.g., a humidifier) is configured to remove at least a portion of the water from the liquid stream to produce a concentrated brine stream enriched in the dissolved salt. In certain cases, the concentrated brine stream is recirculated through the fluidic circuit until the concentrated brine stream reaches a relatively high density (e.g., at least about 10 pounds per gallon) and/or a relatively high salinity (e.g., a total dissolved salt concentration of at least about 25 wt %).
    Type: Application
    Filed: January 11, 2016
    Publication date: November 24, 2016
    Applicant: Gradiant Corporation
    Inventors: Prakash Narayan Govindan, Maximus G. St. John, Steven Lam, Mark Zaloudek, Karim M. Chehayeb, Samar Shah
  • Publication number: 20160339356
    Abstract: Embodiments described herein generally relate to apparatuses that include a vessel comprising a humidification region (e.g., a bubble column humidification region) and a dehumidification region (e.g., a bubble column dehumidification region), and associated systems and methods. In certain embodiments, the apparatuses are configured to include various internal features, such as vapor distribution regions and/or liquid flow control weirs and/or baffles. In some cases, the apparatuses are used in water purification systems, such as desalination systems. The water purification systems may comprise additional devices external to the apparatuses, such as one or more heat exchangers, one or more heating devices, and/or one or more cooling devices.
    Type: Application
    Filed: May 21, 2015
    Publication date: November 24, 2016
    Applicant: Gradiant Corporation
    Inventors: Prakash Narayan Govindan, Steven Lam, Maximus G. St. John
  • Publication number: 20160339357
    Abstract: Embodiments described herein generally relate to apparatuses that include a vessel comprising a humidification region (e.g., a bubble column humidification region) and a dehumidification region (e.g., a bubble column dehumidification region), and associated systems and methods. In certain embodiments, the apparatuses are configured to include various internal features, such as vapor distribution regions and/or liquid flow control weirs and/or baffles. In some cases, the apparatuses are used in water purification systems, such as desalination systems. The water purification systems may comprise additional devices external to the apparatuses, such as one or more heat exchangers, one or more heating devices, and/or one or more cooling devices.
    Type: Application
    Filed: May 21, 2015
    Publication date: November 24, 2016
    Applicant: Gradiant Corporation
    Inventors: Prakash Narayan Govindan, Steven Lam, Maximus G. St. John
  • Publication number: 20160339354
    Abstract: Systems and methods related to desalination systems are described herein. According to some embodiments, the desalination systems are transiently operated and/or configured to facilitate transient operation. In some embodiments, a liquid stream comprising water and at least one dissolved salt is circulated through a fluidic circuit comprising a desalination system. In some embodiments, a portion of the desalination system (e.g., a humidifier) is configured to remove at least a portion of the water from the liquid stream to produce a concentrated brine stream enriched in the dissolved salt. In certain cases, the concentrated brine stream is recirculated through the fluidic circuit until the concentrated brine stream reaches a relatively high density (e.g., at least about 10 pounds per gallon) and/or a relatively high salinity (e.g., a total dissolved salt concentration of at least about 25 wt %).
    Type: Application
    Filed: May 21, 2015
    Publication date: November 24, 2016
    Applicant: Gradiant Corporation
    Inventors: Prakash Narayan Govindan, Maximus G. St. John, Steven Lam, Mark Zaloudek, Karim M. Chehayeb, Samar Shah