Patents by Inventor Pranab Maiti

Pranab Maiti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL SMALL MOLECULE INHIBITORS OF TEAD TRANSCRIPTION FACTORS
    Publication number: 20230113085
    Abstract: The present disclosure compounds, as well as their compositions and methods of use. The compounds inhibit the activity of the TEAD transcription factor, and are useful in the treatment of diseases related to the activity of TEAD transcription factor including, e.g., cancer and other diseases.
    Type: Application
    Filed: March 13, 2020
    Publication date: April 13, 2023
    Inventors: Xu Wu, Pranab Maiti, Chandrasekhar Abbineni, Krishna Chaitanya Talluri, Sunil Kumar Panigrahi, Gopala Krishna Jarugumilli, Yang Sun
  • USP30 inhibitors
    Patent number: 10968172
    Abstract: The application relates to phenyl- or naphthylsulfonamide derivatives of the structural formula (I). The compounds are described as inhibitors of USP30 (ubiquitin specific peptidase 30) useful for the treatment of conditions involving mitochondrial defects including neurodegenerative diseases such as Alzheimer's and Parkinson's or a neoplastic disease such as leukemia.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: April 6, 2021
    Assignee: Mitobridge, Inc.
    Inventors: Arthur Kluge, Bharat Lagu, Pranab Maiti, Sunil Kumar Panigrahi
  • USP30 INHIBITORS
    Publication number: 20200131121
    Abstract: The application relates to phenyl- or naphthylsulfonamide derivatives of the structural formula (I). The compounds are described as inhibitors of USP30 (ubiquitin specific peptidase 30) useful for the treatment of conditions involving mitochondrial defects including neurodegenerative diseases such as Alzheimer's and Parkinson's or a neoplastic disease such as leukemia.
    Type: Application
    Filed: May 14, 2018
    Publication date: April 30, 2020
    Inventors: Arthur Kluge, Bharat Lagu, Pranab Maiti, Sunil Kumar Panigrahi
  • Isopropyl triazolo pyridine compounds
    Patent number: 9809592
    Abstract: The present invention provides a compound of the Formula (I) below: Wherein R1 is selected from the group consisting of H, CH3, CN, CH2CN, C(CH3)2CN, and F; R2 is selected from the group consisting of H, O(C1-C3alkyl)R5, CH2CN, and CN; R3 is selected from the group consisting of H, OCH3, CN, C(CH3)2CN, and CH2CN; R4 is selected from the group consisting of H and CH3; R5 is selected from the group consisting of H, CN, C(CH3)2CN, OCH3, S(O)2CH3, and C(CH3)2OH; provided that at least one selected from the group consisting of R1, R2, R3 and R4 is H; or a pharmaceutically acceptable salt thereof, methods of treating diabetes using the compound and a process for preparing the compound.
    Type: Grant
    Filed: January 6, 2015
    Date of Patent: November 7, 2017
    Assignee: Eli Lilly and Company
    Inventors: Chafiq Hamdouchi, Pranab Maiti, Anne Reifel Miller
  • Phenyl-triazolo-pyridine compounds
    Patent number: 9617263
    Abstract: The present invention provides a compound of the Formula (I) below: wherein R1 is selected from the group consisting of H, CH3, CN, —CH2CN, —C(CH3)2CN, F, Cl, and Br; R2 is selected from the group consisting of H, —O(C1-C3alkylene)R4, —CH2CN, CN, —OCH3, CF2, —C(CH3)2CN, —C(CH3)2, —S(O)2CH3, —S(O)2NH2, and —OCF2; R3 is selected from the group consisting of H, CH3, and —OCH3; and R4 is selected from the group consisting of H, —C(CH3)2CN, —OCH3, —S(O)2CH3, CN, and —C(CH3)2OH; or a pharmaceutical salt thereof, methods of treating type two diabetes using the compound and a process for preparing the compound.
    Type: Grant
    Filed: January 6, 2015
    Date of Patent: April 11, 2017
    Assignee: Eli Lilly and Company
    Inventors: Chafiq Hamdouchi, Pranab Maiti
  • PHENYL-TRIAZOLO-PYRIDINE COMPOUNDS
    Publication number: 20170029420
    Abstract: The present invention provides a compound of the Formula (I) below: wherein R1 is selected from the group consisting of H, CH3, CN, —CH2CN, —C(CH3)2CN, F, Cl, and Br; R2 is selected from the group consisting of H, —O(C1-C3alkylene)R4, —CH2CN, CN, —OCH3, CF2, —C(CH3)2CN, —C(CH3)2, —S(O)2CH3, —S(O)2NH2, and —OCF2; R3 is selected from the group consisting of H, CH3, and —OCH3; and R4 is selected from the group consisting of H, —C(CH3)2CN, —OCH3, —S(O)2CH3, CN, and —C(CH3)2OH; or a pharmaceutical salt thereof, methods of treating type two diabetes using the compound and a process for preparing the compound.
    Type: Application
    Filed: January 6, 2015
    Publication date: February 2, 2017
    Applicant: Eli Lily and Company
    Inventors: Chafiq Hamdouchi, Pranab Maiti
  • ISOPROPYL TRIAZOLO PYRIDINE COMPOUNDS
    Publication number: 20160333005
    Abstract: The present invention provides a compound of the Formula (I) below: Wherein R1 is selected from the group consisting of H, CH3, CN, CH2CN, C(CH3)2CN, and F; R2 is selected from the group consisting of H, O(C1-C3alkyl)R5, CH2CN, and CN; R3 is selected from the group consisting of H, OCH3, CN, C(CH3)2CN, and CH2CN; R4 is selected from the group consisting of H and CH3; R5 is selected from the group consisting of H, CN, C(CH3)2CN, OCH3, S(O)2CH3, and C(CH3)2OH; provided that at least one selected from the group consisting of R1, R2, R3 and R4 is H; or a pharmaceutically acceptable salt thereof, methods of treating diabetes using the compound and a process for preparing the compound.
    Type: Application
    Filed: January 6, 2015
    Publication date: November 17, 2016
    Applicant: ELI LILLY AND COMPANY
    Inventors: Chafiq Hamdouchi, Pranab Maiti, Anne Reifel Miller
  • Spiropiperidine compounds
    Patent number: 8822486
    Abstract: A compound of the formula: or a pharmaceutically acceptable salt thereof as well as a pharmaceutical composition, and a method for treating diabetes.
    Type: Grant
    Filed: November 19, 2010
    Date of Patent: September 2, 2014
    Assignee: Eli Lilly and Company
    Inventors: Chafiq Hamdouchi, Jayana Pankaj Lineswala, Pranab Maiti
  • Spiropiperidine compounds
    Patent number: 8383642
    Abstract: A compound of the formula: or a pharmaceutically acceptable salt thereof as well as a pharmaceutical composition, and a method for treating diabetes.
    Type: Grant
    Filed: October 11, 2010
    Date of Patent: February 26, 2013
    Assignee: Eli Lilly and Company
    Inventors: Chafiq Hamdouchi, Jayana Pankaj Lineswala, Pranab Maiti
  • NOVEL SPIROPIPERIDINE COMPOUNDS
    Publication number: 20120220616
    Abstract: A compound of the formula: or a pharmaceutically acceptable salt thereof as well as a pharmaceutical composition, and a method for treating diabetes.
    Type: Application
    Filed: November 19, 2010
    Publication date: August 30, 2012
    Applicant: ELI LILLY AND COMPANY
    Inventors: Chafiq Hamdouchi, Jayana Pankaj Lineswala, Pranab Maiti
  • Novel Spiropiperidine Compounds
    Publication number: 20110092531
    Abstract: A compound of the formula: or a pharmaceutically acceptable salt thereof as well as a pharmaceutical composition, and a method for treating diabetes.
    Type: Application
    Filed: October 11, 2010
    Publication date: April 21, 2011
    Applicant: ELI LILLY AND COMPANY
    Inventors: Chafiq Hamdouchi, Jayana Pankaj Lineswala, Pranab Maiti