Abstract: A system for monitoring processes of a distributed business application an integration builder tool. The integration builder tool includes a condition editor having a user interface providing an editing area on a display in which to receive a text-based expression of one or more conditions of a business application process. The editing area further includes an operator palette providing a plurality of operators for use in the text based expression of each of the one or more conditions, and a toolbar providing one or more editing tools for editing the text-based expressions.

Abstract: Collating real time comments associated with an event enables a user to provide the real time comments on proceedings occurring in the event. The method of collating real time comments comprises providing real time comments for the event, wherein the real time comments are provided on a communication device. Thereafter, identifying a position parameter value of the real time comment by the communication device and sending the comments data to the central server by the communication device, wherein the comments data comprises real time comments and the position parameter values, followed by processing the comments data by the central sewer. Processing of the comments data would further comprise collating the real time comments of the user with real time comments from the plurality of users. The user comments are thus synced using algorithms, with a single timeline of the respective event stored in the central server.

Abstract: A process for the resolution of isomeric tramadol mixtures comprising: providing a purification stock comprising both cis and trans tramadol; contacting the purification stock with an acid under conditions effective to form an acid salt of the cis and trans tramadol in the purification stock; and separating the cis tramadol acid salt from the trans tramadol to obtain a purified cis tramadol acid salt; and optionally converting the cis tramadol acid salt to cis tramadol or to a pharmaceutically active salt thereof.

Abstract: A system for monitoring processes of a distributed business application an integration builder tool. The integration builder tool includes a condition editor having a user interface providing an editing area on a display in which to receive a text-based expression of one or more conditions of a business application process. The editing area further includes an operator palette providing a plurality of operators for use in the text based expression of each of the one or more conditions, and a toolbar providing one or more editing tools for editing the text-based expressions.

Abstract: A process for preparation of gabapentin comprising a step of obtaining 1,1-cyclohexane diacetic acid monoamide from 1,1-cyclohexane diacetic acid anhydride, wherein said reaction is characterized by the use of ammonia precursor or pre-generated ammonia-isopropanol solution. The invention further discloses preparation of gabapentin and isolation of gabapentin in polymorphic Form II with high yield and purity.

Abstract: A process for the resolution of isomeric tramadol mixtures comprising: providing a purification stock comprising both cis and trans tramadol; contacting the purification stock with an acid under conditions effective to form an acid salt of the cis and trans tramadol in the purification stock; and separating the cis tramadol acid salt from the trans tramadol to obtain a purified cis tramadol acid salt; and optionally converting the cis tramadol acid salt to cis tramadol or to a pharmaceutically active salt thereof.

Abstract: Disclosed herein is a process for preparation of carvedilol substantially free from its bis-impurity comprises the reaction of 4-(2,3-epoxypropoxy)carbazole and 2-(2-methoxyphenoxy)ethylamine in a polar aprotic solvent media; followed by isolation of carvediol from the reaction mass as an acid addition salt and subsequent conversion into pure carvedilol.

Abstract: Metoprolol manufacturing process with optimized reaction temperatures and reactant molar ratios, to avoid the manufacture of excessive epoxide intermediates, thus avoiding the need for purification of epoxide intermediates, thus achieving higher yields and higher-purity product than that seen in the prior art teachings.