Abstract: A dressing interface includes a base that has an aperture and a plurality of microneedles that are attached to the base and disposed over the aperture. The interface also includes a port that is configured to receive a fluid conductor and a conduit that couples the port and the aperture. Each of the microneedles contains a passageway that is fluidly coupled to the aperture. The interface may be used with a drape that is placed over a tissue site. The interface may provide communication between the tissue site and a reduced-pressure source through the microneedles piercing the drape rather than by cutting a hole in the drape.

Abstract: This disclosure describes devices, systems, and methods related to dressings with regions with different adhesive properties, and manufacture and use thereof. An illustrative dressing includes a first region including a first adhesive material. The first adhesive material has a first tackiness. The dressing further includes at least a second region including a second adhesive material. The second adhesive material has a second tackiness in a first phase and a third tackiness in a second phase. The third tackiness is greater than the second tackiness. The first adhesive material is configured to maintain the first tackiness when the second adhesive material in the second phase.

Abstract: A dressing interface includes a base that has an aperture and a plurality of microneedles that are attached to the base and disposed over the aperture. The interface also includes a port that is configured to receive a fluid conductor and a conduit that couples the port and the aperture. Each of the microneedles contains a passageway that is fluidly coupled to the aperture. The interface may be used with a drape that is placed over a tissue site. The interface may provide communication between the tissue site and a reduced-pressure source through the microneedles piercing the drape rather than by cutting a hole in the drape.

Abstract: Dressings are provided herein having a manifold and a biopolymer layer. The configuration and/or compressibility of the manifold and the biopolymer layer can allow for reduced tissue ingrowth and promote wound healing. Methods of making and using the dressings are also provided herein.

Abstract: In one example embodiment, a system for stimulating healing of tissue at a wound site is disclosed. The system comprises a dressing including a porous pad and a drape covering the pad at a wound site for maintaining negative pressure at a wound site, a negative- pressure source including a pump and an electric motor to generate a pump pressure for applying to the wound site, and a first pressure sensor for sensing the pump pressure. The system further comprises a controller coupled to the first pressure sensor and electric motor and a regulator coupled to the controller for inducing leakage into the therapeutic environment of the system to maintain a minimum level of fluid flow within the dressing.

Abstract: A dressing for treating a tissue site with negative pressure may include a bioresorbable manifold layer, which may include a first surface, a second surface opposite the first surface, a thickness. The bioresorbable manifold layer may include a plurality of sacrificial zones configured to degrade upon placement of the bioresorbable manifold layer with respect to the tissue site and application of negative pressure to the bioresorbable manifold layer so as to allow communication of negative pressure between the first surface and the second surface. The bioresorbable manifold layer may include a bioresorbable manifolding structure formed from a first bioresorbable composition and comprising a plurality of apertures corresponding to each of the plurality of sacrificial zones. The bioresorbable manifold layer may also include a second bioresorbable composition disposed within each of the plurality of apertures to form the sacrificial zones.

Abstract: Dressings are provided herein having a manifold and a biopolymer layer. The configuration and/or compressibility of the manifold and the biopolymer layer can allow for reduced tissue ingrowth and promote wound healing. Methods of making and using the dressings are also provided herein.

Abstract: An assembly includes a drape substantially sealable over a wound bed and a trackpad configured to couple a tube to the drape and allow the tube to provide suction to the wound bed. The assembly also includes a vent opening in the drape, a filter coupled to the drape and communicating with the vent opening, a cover coupled to the drape and movable between a first position to cover the vent opening and filter and a second position to uncover the vent opening and the filter, and a fluid indicator coupled to the drape and operable to provide a visual indication that fluid build-up is present in the wound bed.

Abstract: The present technology generally relates to a biomaterial that includes a thiolated biopolymer and one or more agents that include growth factors, peptides, or combinations thereof, where the one or more agents are conjugated to the thiolated biopolymer. Also disclosed herein are wound dressings that include the biomaterial of the present technology, methods of treating a wound upon application of the wound dressing, and kits including the wound dressing and instructions for use.

Abstract: Dressings for treating a tissue site with negative pressure are disclosed, which may include a dressing having multiple layers and incorporating a material adapted to neutralize proteolytic enzymes. In one example embodiment, a dressing may include a first layer comprising a hydrophobic gel having a plurality of apertures. A material adapted to neutralize proteolytic enzymes may be applied to a surface of the first layer. The dressing may further include a second layer comprising a fenestrated film and coupled to the first layer. Additionally, the dressing may include a third layer comprising a manifold, which in some instances may be a polymeric foam. The dressing may further include a fourth layer comprising a polymer drape.

Abstract: Provided are systems, dressings, and methods suitable for treating a tissue site, such as an incision or linear wound, for example. The systems, dressings, and methods relate to a dressing assembly that may include a dressing bolster, a comfort layer, and a polymeric enhancement layer. The dressing bolster may include foam and may have a first side and a second side. A first side of the comfort layer may be coupled to the second side of the dressing bolster, and a first side of the polymeric enhancement layer may be coupled to the second side of the comfort layer. An opposing second side of the polymeric enhancement layer may be configured to directly contact the tissue site. Other systems, dressings, apparatuses, and methods are disclosed.

Abstract: A dressing interface includes a base that has an aperture and a plurality of microneedles that are attached to the base and disposed over the aperture. The interface also includes a port that is configured to receive a fluid conductor and a conduit that couples the port and the aperture. Each of the microneedles contains a passageway that is fluidly coupled to the aperture. The interface may be used with a drape that is placed over a tissue site. The interface may provide communication between the tissue site and a reduced-pressure source through the microneedles piercing the drape rather than by cutting a hole in the drape.

Abstract: A system for use in treating a tissue site with negative pressure, which may comprise a dressing or tissue interface and a plurality of standoffs for storing and releasing a biocompatible polymer to the tissue site. The standoff may be cells or closed-end cells. In some examples, the biocompatible polymer may comprise collagen, oxidized regenerated cellulose, or a combination thereof. Method for using and manufacturing the dressing or tissue interface may also be disclosed.

Abstract: Dressings are provided herein having a manifold and a biopolymer layer. The configuration and/or compressibility of the manifold and the biopolymer layer can allow for reduced tissue ingrowth and promote wound healing. Methods of making and using the dressings are also provided herein.

Abstract: An assembly includes a drape substantially sealable over a wound bed and a trackpad configured to couple a tube to the drape and allow the tube to provide suction to the wound bed. The assembly also includes a vent opening in the drape, a filter coupled to the drape and communicating with the vent opening, a cover coupled to the drape and movable between a first position to cover the vent opening and filter and a second position to uncover the vent opening and the filter, and a fluid indicator coupled to the drape and operable to provide a visual indication that fluid build-up is present in the wound bed.

Abstract: Disclosed are photo-responsive pressure sensitive adhesives, wound dressings that contain the photo-responsive pressure sensitive adhesives, and methods to remove the wound dressing. The photo-responsive pressure sensitive adhesive comprises a viscoelastic polymeric matrix. The viscoelastic polymeric matrix comprises a polymer that includes at least a first polymeric segment and at least a second polymeric segment that are each covalently linked together through a photo-cleavable moiety. The photo-cleavable moiety is capable of photolytic cleavage of the covalent bonds formed between the moiety and the first and/or second polymeric segments, respectively, in response to electromagnetic radiation.