Patents by Inventor Prathap Sreedharan Nair
Prathap Sreedharan Nair has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11952380Abstract: The invention relates to substituted bicyclic heterocyclic compounds of formula (I), pharmaceutically acceptable salts thereof and pharmaceutical compositions for treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme. The invention also relates to methods of treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme.Type: GrantFiled: May 6, 2022Date of Patent: April 9, 2024Assignee: LUPIN LIMITEDInventors: Prathap Sreedharan Nair, Ganesh Bhausaheb Gudade, Sachin Sethi, Dipak Raychand Lagad, Chetan Sanjay Pawar, Mahadeo Bhaskar Tryambake, Chaitanya Prabhakar Kulkarni, Anil Kashiram Hajare, Balasaheb Arjun Gore, Sanjeev Anant Kulkarni, Milind Dattatraya Sindkhedkar, Venkata P. Palle, Rajender Kumar Kamboj
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Publication number: 20230119316Abstract: Disclosed are compounds of the general formula (I), its tautomeric form, its stereoisomer, its pharmaceutically acceptable salt, its polymorph, or solvate thereof, wherein, ring A, ring B, R1 to R4, and n are as defined herein, for use as SOS1 inhibitors in the treatment of proliferative, infectious and RASopathy diseases or disorders. Also disclosed are methods of synthesizing the compound of formula I, pharmaceutical compositions containing the compound of formula I, method of treatment of proliferative, infectious and RASopathy diseases or disorder, for example, a cancer, by administering the said compound and combinations of the compound of formula I with other active ingredients.Type: ApplicationFiled: December 27, 2020Publication date: April 20, 2023Inventors: Sanjay Pralhad Kurhade, Prathap Sreedharan Nair, Sachin Sethi, Manojkumar Ramprasad Shukla, Milind Dattatraya Sindkhedkar, Venkata P. Palle, Rajender Kumar Kamboj, Samiron Phukan, Pradeep Rangrao Patil, Sayyed Majid, Ramesh Phadatare, Navnath Walke, Vipul Pachpute, Balasaheb Gore, Vikas Tambe, Rohan Limaye, Avadhut Bhosale, Sachin Mahangare
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Publication number: 20230066014Abstract: The invention relates to substituted nucleoside analogues of formula (I), pharmaceutically acceptable salts thereof and pharmaceutical compositions for treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme. The invention also relates to methods of treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme.Type: ApplicationFiled: December 2, 2020Publication date: March 2, 2023Applicant: Lupin LimitedInventors: Prathap Sreedharan NAIR, Ganesh Bhausaheb GUDADE, Shankar Bhaskar BHAGWAT, Amol Maruti YADAV, Chaitanya Prabhakar KULKARNI, Milind Dattatraya SINDKHEDKAR, Venkata P. PALLE, Rajender Kumar KAMBOJ
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Publication number: 20230013778Abstract: Disclosed are compounds of the general formula (I), its tautomeric form, its stereoisomer, its pharmaceutically acceptable salt, its polymorph, or solvate thereof, Formula (I) wherein, ring A, R1 to R5, X, Y, m, and n are as defined herein, for use as SOS1 inhibitors in the treatment of proliferative, infectious and RASopathy diseases or disorders. Also disclosed are methods of synthesizing the compound of formula I, pharmaceutical compositions containing the compound of formula I, method of treatment of proliferative, infectious and RASopathy diseases or disorder, for example, a cancer, by administering the said compound and combinations of the compound of formula I with other active ingredients.Type: ApplicationFiled: November 28, 2020Publication date: January 19, 2023Inventors: Sachin Sethi, Prathap Sreedharan Nair, Manojkumar Ramprasad Shukla, Milind Dattatraya Sindkhedkar, Venkata P. Palle, Rajender Kumar Kamboj, Samiron Phukan, Pradeep Rangrao Patil, Ganesh Kakade, Nilesh Raghunath Khedkar, Dagadu Dube, Vikas Sitaram Tambe, Sudhakar Maruti Balgude, Pradip Balu Wagh
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Publication number: 20220315589Abstract: The invention relates to substituted nucleoside analogues of formula (I), pharmaceutically acceptable salts thereof and pharmaceutical compositions for treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme. The invention also relates to methods of treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme.Type: ApplicationFiled: June 9, 2020Publication date: October 6, 2022Inventors: Prathap Sreedharan Nair, Ganesh Bhausaheb Gudade, Mahadeo Bhaskar Tryambake, Chetan Sanjay Pawar, Dipak Raychand Lagad, Chaitanya Prabhakar Kulkarni, Milind Dattatraya Sindkhedkar, Venkata P. Palle, Rajender Kumar Kamboj
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Patent number: 11459330Abstract: The invention relates to substituted bicyclic heterocyclic compounds of formula (I), pharmaceutically acceptable salts thereof and pharmaceutical compositions for treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme. The invention also relates to methods of treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme.Type: GrantFiled: December 13, 2018Date of Patent: October 4, 2022Assignee: LUPIN LIMITEDInventors: Prathap Sreedharan Nair, Ganesh Bhausaheb Gudade, Sachin Sethi, Dipak Raychand Lagad, Chetan Sanjay Pawar, Mahadeo Bhaskar Tryambake, Chaitanya Prabhakar Kulkarni, Anil Kashiram Hajare, Balasaheb Arjun Gore, Sanjeev Anant Kulkarni, Milind Dattatraya Sindkhedkar, Venkata P. Palle, Rajender Kumar Kamboj
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Publication number: 20220267339Abstract: The invention relates to substituted bicyclic heterocyclic compounds of formula (I), pharmaceutically acceptable salts thereof and pharmaceutical compositions for treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme. The invention also relates to methods of treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme.Type: ApplicationFiled: May 6, 2022Publication date: August 25, 2022Applicant: LUPIN LIMITEDInventors: Prathap Sreedharan Nair, Ganesh Bhausaheb Gudade, Sachin Sethi, Dipak Raychand Lagad, Chetan Sanjay Pawar, Mahadeo Bhaskar Tryambake, Chaitanya Prabhakar Kulkarni, Anil Kashiram Hajare, Balasaheb Arjun Gore, Sanjeev Anant Kulkarni, Milind Dattatraya Sindkhedkar, Venkata P. Palle, Rajender Kumar Kamboj
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Publication number: 20210163486Abstract: The invention relates to substituted bicyclic heterocyclic compounds of formula (I), pharmaceutically acceptable salts thereof and pharmaceutical compositions for treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme. The invention also relates to methods of treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme.Type: ApplicationFiled: December 13, 2018Publication date: June 3, 2021Applicant: LUPIN LIMITEDInventors: Prathap Sreedharan Nair, Ganesh Bhausaheb Gudade, Sachin Sethi, Dipak Raychand Lagad, Chetan Sanjay Pawar, Mahadeo Bhaskar Tryambake, Chaitanya Prabhakar Kulkarni, Anil Kashiram Hajare, Balasaheb Arjun Gore, Sanjeev Anant Kulkarni, Milind Dattatraya Sindkhedkar, Venkata P. Palle, Rajender Kumar Kamboj
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Patent number: 9493396Abstract: The invention relates to naphthalene compounds of Formula (I) and their pharmaceutically acceptable salts, wherein the substituents are as described herein, and their use in medicine for the treatment of diseases, disorders associated with the modulation of calcium sensing receptor modulators (Ca SR). The invention also relates to pharmaceutical compositions containing such compounds in treating diseases disorders associated with calcium sensing receptor modulators (Ca SR) channel modulators.Type: GrantFiled: August 26, 2014Date of Patent: November 15, 2016Assignee: LUPIN ATLANTIS HOLDINGS SAInventors: Prathap Sreedharan Nair, Ganesh Bhausaheb Gudade, Mahadeo Bhaskar Tryambake, Chetan Sanjay Pawar, Sanjeev Anant Kulkarni, Venkata P. Palle, Rajender Kumar Kamboj
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Publication number: 20160214924Abstract: The invention relates to naphthalene compounds of Formula (I) and their pharmaceutically acceptable salts, wherein the substituents are as described herein, and their use in medicine for the treatment of diseases, disorders associated with the modulation of calcium sensing receptor modulators (Ca SR). The invention also relates to pharmaceutical compositions containing such compounds in treating diseases disorders associated with calcium sensing receptor modulators (Ca SR) channel modulators.Type: ApplicationFiled: August 26, 2014Publication date: July 28, 2016Inventors: Prathap Sreedharan NAIR, Ganesh Bhausaheb GUDADE, Mahadeo Bhaskar TRYAMBAKE, Chetan Sanjay PAWAR, Sanjeev Anant KULKARNI, Venkata P. PALLE, Rajender Kumar KAMBOJ
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Patent number: 7691889Abstract: Novel compounds belonging to the class of oxazolidinones possessing potent antimycobacterial properties especially useful in the treatment of acid fast organisms such as Mycobacterium tuberculosis, Mycobacterium avium-intracellular complex, M. fortuitum and M. kansai. The compound and its pharmaceutically acceptable salts act as antibacterial agents. Also mentioned is a method for inhibiting growth of mycobacterial cells as well as a method of treating mycobacterial conditions such as Mycobacterium tuberculosis, drug resistant Mycobacterium tuberculosis, Mycobacterium avium-intracellular complex, M. fortuitum and M. kansai., including administering an antimycobacterially effective amount of the compound and/or pharmaceutically acceptable salts. There is also mentioned a process for the manufacture of the compound or its pharmaceutically acceptable salts.Type: GrantFiled: March 18, 2005Date of Patent: April 6, 2010Assignee: Lupin LimitedInventors: Sudershan Kumar Arora, Vijaykumar Jagdishwar Patil, Prathap Sreedharan Nair, Prasad Purushottam Dixit, Shankar Ajay, Rakesh Kumar Sinha