Abstract: Modified-release pharmaceutical compositions of ruxolitinib or a pharmaceutically acceptable salt thereof are disclosed. Preferably, the invention relates to oral modified-release pharmaceutical compositions of ruxolitinib, which enable once-daily administration. Oral modified-release compositions of ruxolitinib, methods for their administration, processes for their preparation, and use of these compositions for treatment of diseases treatable by ruxolitinib are also described.

Abstract: Disclosed is a system for translating data, extracted from disparate data sources, into a homogeneous dataset to provide meaningful information. The database schema definition module defines a database schema in order to extract meaningful information pertaining to a specific use-case. The data source determination module determines one or more disparate data sources pertinent to extract the meaningful information. The data extraction module extracts heterogeneous dataset from the one or more disparate data sources. The data extraction module further passes the heterogeneous dataset to a Data-Translate Markup Language (DTML) executer to translate the heterogeneous dataset into a homogeneous dataset. The data translation module translates the heterogeneous dataset into the homogeneous dataset by using at least one data adapter.

Abstract: Disclosed is a system for translating data, extracted from disparate data sources, into a homogeneous dataset to provide meaningful information. The database schema definition module defines a database schema in order to extract meaningful information pertaining to a specific use-case. The data source determination module determines one or more disparate data sources pertinent to extract the meaningful information. The data extraction module extracts heterogeneous dataset from the one or more disparate data sources. The data extraction module further passes the heterogeneous dataset to a Data-Translate Markup Language (DTML) executer to translate the heterogeneous dataset into a homogeneous dataset. The data translation module translates the heterogeneous dataset into the homogeneous dataset by using at least one data adapter.

Abstract: A pulse width modulation control circuit for a high frequency series resonant AC/DC converter suitable for use in computing and network equipment such as personal computers, servers and high-speed routers includes an auxiliary transformer, a zero crossing detector, a delay circuit, a synchronization circuit and an output circuit.

Abstract: A high-frequency resonant sine wave DC to AC inverter suitable for use in a personal computer (PC) power supply includes a full-bridge inverter, a resonant circuit, a phase shift modulation circuit, and a resonant gate driver. The resonant gate driver provides sinusoidal gate drive signals to the full-bridge inverter enabling highly efficient operation on the inverter.

Abstract: A pulse width modulation control circuit for a high frequency series resonant AC/DC converter suitable for use in computing and network equipment such as personal computers, servers and high-speed routers includes an auxiliary transformer, a zero crossing detector, a delay circuit, a synchronization circuit and an output circuit. The pulse width modulation control circuit provides phase and frequency synchronized gating signals enabling high conversion efficiency, with little or no cross conduction losses and increased effective pulse width.

Abstract: A high-frequency resonant sine wave DC to AC inverter suitable for use in a personal computer (PC) power supply includes a full-bridge inverter, a resonant circuit, a phase shift modulation circuit, and a resonant gate driver. The resonant gate driver provides sinusoidal gate drive signals to the full-bridge inverter enabling highly efficient operation on the inverter.

Abstract: An AC/DC converter for outputting high current, low voltage output from a high frequency AC source is described. The AC/DC converter includes two resonant components, a resonant circuit having a capacitor and an inductor. Both of the resonant components are connected in series and form a series resonant circuit. The converter further includes a transformer having a primary winding with a center tap to a secondary winding. The resonant circuit and the primary winding are connected in series. The center tap is connected to an output filter and a load, while the other two ends of the secondary winding are connected to two controlled switches, respectively. A drain of each of the two controlled switches is connected to opposite ends of the secondary winding, while each of the sources of the two controlled switches are interconnected. Two anti-parallel diodes are respectively connected across the two controlled switches. Two capacitors are also respectively connected across the two controlled switches.