Patents by Inventor Premal H. Patel

Premal H. Patel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIOMARKERS AND METHODS OF TREATMENT
    Publication number: 20140037625
    Abstract: The present invention concerns cancer biomarkers. In particular, the invention concerns c-met as biomarkers for patient selection and patient prognosis in cancer, as well as methods of therapeutic treatment, articles of manufacture and methods for making them, diagnostic kits, methods of detection and methods of advertising related thereto.
    Type: Application
    Filed: October 4, 2013
    Publication date: February 6, 2014
    Applicant: GENENTECH, INC.
    Inventors: Premal H. Patel, Amy C. Peterson, Robert L. Yauch, Jiping Zha
  • BIOMARKERS AND METHODS OF TREATMENT
    Publication number: 20120089541
    Abstract: The present invention concerns cancer biomarkers. In particular, the invention concerns c-met as biomarkers for patient selection and patient prognosis in cancer, as well as methods of therapeutic treatment, articles of manufacture and methods for making them, diagnostic kits, methods of detection and methods of advertising related thereto.
    Type: Application
    Filed: August 31, 2011
    Publication date: April 12, 2012
    Applicant: Genentech, Inc.
    Inventors: Premal H. Patel, Amy C. Peterson, Robert L. Yauch, Jiping Zha
  • TREATMENT METHODS
    Publication number: 20110287003
    Abstract: The present invention relates generally to the fields of molecular biology and growth factor regulation. More specifically, the invention relates to therapies for the treatment of pathological conditions, such as cancer.
    Type: Application
    Filed: May 16, 2011
    Publication date: November 24, 2011
    Applicant: Genentech, Inc.
    Inventors: Premal H. Patel, Amy C. Peterson
  • DNA polymerase mutant having one or more mutations in the active site
    Patent number: 6602695
    Abstract: This invention provides a DNA polymerase that is a mutant form of a naturally occurring DNA polymerase, of which one or more amino acids in the active site are mutated. The DNA polymerase mutant of this invention is characterized by altered fidelity or altered enzymatic activity in comparison with the naturally occurring DNA polymerase. For example, the DNA polymerase mutant provides increased enzymatic activity, altered dNTP/rNTP specificity, or enhanced fidelity. In one aspect of the invention, the naturally occurring DNA polymerase comprises an amino acid sequence motif: AspTyrSerGlnIleGluLeuArg in the active site. In another aspect of the invention, the naturally occurring DNA polymerase comprises an amino acid sequence motif: LeuLeuValAlaLeuAspTyrSerGlnIleGluLeuArg in the active site.
    Type: Grant
    Filed: October 16, 2001
    Date of Patent: August 5, 2003
    Assignee: University of Washington
    Inventors: Premal H. Patel, Lawrence A. Loeb
  • DNA polymerase mutant having one or more mutations in the active site
    Publication number: 20020132249
    Abstract: This invention provides a DNA polymerase that is a mutant form of a naturally occurring DNA polymerase, of which one or more amino acids in the active site are mutated. The DNA polymerase mutant of this invention is characterized by altered fidelity or altered enzymatic activity in comparison with the naturally occurring DNA polymerase. For example, the DNA polymerase mutant provides increased enzymatic activity, altered dNTP/rNTP specificity, or enhanced fidelity. In one aspect of the invention, the naturally occurring DNA polymerase comprises an amino acid sequence motif: AspTyrSerGlnIleGluLeuArg in the active site. In another aspect of the invention, the naturally occurring DNA polymerase comprises an amino acid sequence motif: LeuLeuValAlaLeuAspTyrSerGlnIleGluLeuArg in the active site.
    Type: Application
    Filed: October 16, 2001
    Publication date: September 19, 2002
    Inventors: Premal H. Patel, Lawrence A. Loeb
  • DNA polymerase mutant having one or more mutations in the active site
    Patent number: 6329178
    Abstract: This invention provides a DNA polymerase that is a mutant form of a naturally occurring DNA polymerase, of which one or more amino acids in the active site are mutated. The DNA polymerase mutant of this invention is characterized by altered fidelity or altered enzymatic activity in comparison with the naturally occurring DNA polymerase. For example, the DNA polymerase mutant provides increased enzymatic activity, altered dNTP/rNTP specificity, or enhanced fidelity. In one aspect of the invention, the naturally occurring DNA polymerase comprises an amino acid sequence motif: AspTyrSerGlnIleGluLeuArg in the active site. In another aspect of the invention, the naturally occurring DNA polymerase comprises an amino acid sequence motif: LeuLeuVa1AlaLeuAspTyrSerGlnIleGluLeuArg in the active site.
    Type: Grant
    Filed: January 14, 2000
    Date of Patent: December 11, 2001
    Assignee: University of Washington
    Inventors: Premal H. Patel, Lawrence A. Loeb