Patents by Inventor Pritmohinder S. Gill

Pritmohinder S. Gill has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11987834
    Abstract: The present disclosure relates to acetaminophen protein adducts and methods of diagnosing acetaminophen toxicity using the acetaminophen protein adducts.
    Type: Grant
    Filed: June 6, 2019
    Date of Patent: May 21, 2024
    Assignee: BioVentures, LLC
    Inventors: Laura P. James, Jack Hinson, Dean Roberts, Pritmohinder S. Gill
  • Publication number: 20190300931
    Abstract: The present disclosure relates to acetaminophen protein adducts and methods of diagnosing acetaminophen toxicity using the acetaminophen protein adducts.
    Type: Application
    Filed: June 6, 2019
    Publication date: October 3, 2019
    Inventors: Laura P. James, Jack Hinson, Dean Roberts, Pritmohinder S. Gill
  • Patent number: 10351897
    Abstract: The present disclosure relates to acetaminophen protein adducts and methods of diagnosing acetaminophen toxicity using the acetaminophen protein adducts. The present disclosure provides acetaminophen (APAP)-protein adducts and methods of detecting acetaminophen-induced toxicity in a subject using APAP-protein adducts. One aspect of the present disclosure provides an APAP-protein adduct for diagnosing acetaminophen-induced toxicity. According to the present disclosure, the inventors have identified proteins that are modified by N-acetyl-pbenzoquinoneimine (NAPQI) in subjects with acetaminophen-induced toxicity. Non-limiting examples of proteins modified by NAPQI include betaine-homocysteine S-methyltransferase 1, cytoplasmic aspartate aminotransferase, 1,4-alpha-glucan branching enzyme, formimidoyltransferase-cyclodeaminase, and dystrophin.
    Type: Grant
    Filed: February 13, 2015
    Date of Patent: July 16, 2019
    Assignee: BioVentures, LLC
    Inventors: Laura P. James, Jack Hinson, Dean Roberts, Pritmohinder S. Gill
  • Publication number: 20170175166
    Abstract: The present disclosure relates to acetaminophen protein adducts and methods of diagnosing acetaminophen toxicity using the acetaminophen protein adducts. The present disclosure provides acetaminophen (APAP)-protein adducts and methods of detecting acetaminophen-induced toxicity in a subject using APAP-protein adducts. One aspect of the present disclosure provides an APAP-protein adduct for diagnosing acetaminophen-induced toxicity. According to the present disclosure, the inventors have identified proteins that are modified by N-acetyl-pbenzoquinoneimine (NAPQI) in subjects with acetaminophen-induced toxicity. Non-limiting examples of proteins modified by NAPQI include betaine-homocysteine 5-methyltransferase 1, cytoplasmic aspartate aminotransferase, 1,4-alpha-glucan branching enzyme, formimidoyltransferase-cyclodeaminase, and dystrophin.
    Type: Application
    Filed: February 13, 2015
    Publication date: June 22, 2017
    Inventors: Laura P. James, Jack Hinson, Dean Roberts, Pritmohinder S. Gill