Patents by Inventor Przemyslaw Twardowski

Przemyslaw Twardowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for generating angiostatin
    Publication number: 20060099671
    Abstract: The invention provides methods of generating angiostatin in vitro comprising contacting plasminogen with a plasminogen activator and a sulfhydryl donor or contacting plasmin with a sulfhydryl donor. The invention also provides a method of treating angiogenic diseases by administering to an animal suffering from such a disease a sulfhydryl donor, a plasminogen activator, or a combination of a sulfhydryl donor and a plasminogen activator. The invention further comprises a composition for generating angiostatin comprising a sulfhydryl donor and a plasminogen activator. The invention also provides a container holding a sulfhydryl donor and/or a plasminogen activator, said container having a label thereon instructing administration of the sulfhydryl donor and/or plasminogen activator to an animal suffering from an angiogenic disease.
    Type: Application
    Filed: December 22, 2005
    Publication date: May 11, 2006
    Inventors: Gerald Soff, Stephen Gately, Przemyslaw Twardowski
  • Methods and compositions for generating angiostatin
    Patent number: 6576609
    Abstract: The invention provides a method of treating a neoplastic disease in a human by administering a therapeutically effective amount of plasminogen activator effective to increase the amount of angiostatin present in the human to treat the disease. The invention also provides a method of treating a neoplastic disease in a human by administering a therapeutically effective amount of plasminogen activator and sulfhydryl donor effective to increase the amount of angiostatin present in the human to treat said disease.
    Type: Grant
    Filed: December 16, 1997
    Date of Patent: June 10, 2003
    Assignee: Northwestern University
    Inventors: Gerald Soff, Stephen T. Gately, Przemyslaw Twardowski
  • Methods and compositions for generating angiostatin
    Patent number: 5801012
    Abstract: The invention provides a method of generating angiostatin in vitro comprising contacting plasminogen or plasmin with a plasminogen activator and a sulfhydryl donor.
    Type: Grant
    Filed: September 17, 1996
    Date of Patent: September 1, 1998
    Assignee: Northwestern University
    Inventors: Gerald Soff, Stephen T. Gately, Przemyslaw Twardowski