Patents by Inventor Pu Sun
Pu Sun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240148850Abstract: The present disclosure provides an N protein epitope mutation marker for preparing an epitope deletion-marked vaccine strain of type II porcine reproductive and respiratory syndrome virus (PRRSV) and use thereof, belonging to the technical field of biological products. In the mutation marker, one or more amino acids are mutated based on an epitope sequence at positions 92 to 103 of a C-terminal of an N protein of the type II PRRSV; and the epitope mutation marker has an amino acid sequence shown in SEQ ID NO: 1, where X1 is selected from the group consisting of T, P, and A; and X2 is selected from the group consisting of V and A.Type: ApplicationFiled: March 17, 2022Publication date: May 9, 2024Applicant: Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural SciencesInventors: Jing ZHANG, Zengjun LU, Kun LI, Pu SUN, Jian WANG, Yimei CAO, Huifang BAO, Zhixun ZHAO, Pinghua LI, Yuanfang FU, Xueqing MA, Hong YUAN, Xingwen BAI, Qiang ZHANG, Dong LI, Zaixin LIU
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Publication number: 20240088970Abstract: A method and an apparatus for feeding back channel information of a delay-Doppler domain, and an electronic device. The method for feeding back channel information of a delay-Doppler domain in embodiments of this application includes: a first device sends target feedback information to a second device, where the target feedback information is associated with target channel information, the target channel information is all or part of channel information of a delay-Doppler domain obtained by the first device performing channel estimation on a target signal, and the target signal is a signal sent by the second device or a third device to the first device.Type: ApplicationFiled: November 20, 2023Publication date: March 14, 2024Applicant: VIVO MOBILE COMMUNICATION CO., LTD.Inventors: Bule SUN, Dajie JIANG, Pu YUAN
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Patent number: 11884647Abstract: The disclosure provides compounds, and compositions, including pharmaceutical compositions, kits that include the compounds, and methods of using (or administering) and making the compounds. The disclosure further provides compounds or compositions thereof for use in a method of modulating PLXDC1 (TEM7) and/or PLXDC2 or killing pathogenic blood vessles. The disclosure further provides compounds or compositions thereof for use in a method of treating a disease, disorder, or condition that is mediated, at least in part, by PEDF receptors or by angiogenesis.Type: GrantFiled: October 16, 2020Date of Patent: January 30, 2024Assignees: The Regents of the University of California, Atengen, Inc.Inventors: Hui Sun, Pu Sun, Guo Cheng, Adrian Chichuen Au, Ming Zhong
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Publication number: 20230008831Abstract: The present invention provides a two-step auto-injection apparatus consisting of a housing, a protective sleeve cylinder, a pre-filled injection assembly and a drive feedback apparatus, wherein the pre-filled injection assembly is loaded into the housing, and the protective sleeve cylinder covers a needle of the pre-filled injection assembly, so that the protective sleeve cylinder directly contacts an injecting portion and the function of injection can be realized by pressing to trigger the drive feedback apparatus during use, thereby facilitating quick operation with a needle tip hidden in the whole process; the drive feedback apparatus of a piston in a needle cylinder is driven to combine a release mechanism with an ejection mechanism and a feedback mechanism, and the release mechanism is triggered by pressing the protective sleeve cylinder, so that the ejection mechanism is released, and the ejection mechanism interacts with the feedback mechanism in a form of collision, for example, to generate a sound siType: ApplicationFiled: May 12, 2020Publication date: January 12, 2023Applicant: Suzhou Hengrui Hongyuan Medical Technology Co., Ltd.Inventors: Lin HUANG, Pu SUN, Can SUN
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Patent number: 11250593Abstract: An apparatus for use with a medical system, the medical system comprising a medical device configured to treat and/or image a patient, includes: an input configured to receive an image from a camera, the camera configured to view at least a part of the patient and/or at least a part of the medical system; a processing unit configured to replace a damaged-pixel value in the image corresponding with a damaged pixel in the camera that is damaged due to radiation resulted from an operation of the medical device; and an output for outputting an improved image having less noise compared to the image received from the camera.Type: GrantFiled: June 1, 2020Date of Patent: February 15, 2022Assignee: Varian Medical Systems, IncInventors: Paul Pu Sun, Eric Michael Stimmann
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Publication number: 20210374999Abstract: An apparatus for use with a medical system, the medical system comprising a medical device configured to treat and/or image a patient, includes: an input configured to receive an image from a camera, the camera configured to view at least a part of the patient and/or at least a part of the medical system; a processing unit configured to replace a damaged-pixel value in the image corresponding with a damaged pixel in the camera that is damaged due to radiation resulted from an operation of the medical device; and an output for outputting an improved image having less noise compared to the image received from the camera.Type: ApplicationFiled: June 1, 2020Publication date: December 2, 2021Inventors: Paul Pu SUN, Eric Michael STIMMANN
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Publication number: 20210363625Abstract: A mask strip, comprising: a plurality of mask units (2) in a first direction; each of the mask units (2) comprising a mask region (3) and a non-mask region (11) surrounding the mask region (3), the non-mask region (11) comprising a side region (4) and an original stress concentration region (6) inside the side region (4); each of the mask units (2) further comprising a stress concentration structure, wherein the stress concentration structure is within a part of the side region (4) other than the original stress concentration region (6). Also discloses a mask plate and a method of fabricating a mask strip.Type: ApplicationFiled: January 23, 2018Publication date: November 25, 2021Applicants: ORDOS YUANSHENG OPTOELECTRONICS CO., LTD., BOE TECHNOLOGY GROUP CO., LTD.Inventors: Jian Zhang, Chunchieh Huang, Zhiming Lin, Xinjian Zhang, Qi Wang, Zhiyuan Hao, De Zhang, Dejian Liu, Zhen Wang, Pu Sun
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Publication number: 20210364912Abstract: The present disclosure provides a mask tension frame and a mask tension process, where the mask tension frame includes a frame body and a supporting rib. The frame body is provided with a first surface, a second surface, and an opening. The first surface and the second surface are oppositely disposed, and the opening is recessed in the direction from the first surface toward the second surface. The supporting rib spans the opening of the frame body. A surface of the supporting rib for supporting the mask is higher than the first surface with respect to the second surface. When the mask is being tensed by the mask tension frame, at least a portion of the mask is supported by the supporting rib and at least a portion of the mask adjacent to an edge of the mask is supported by the first surface.Type: ApplicationFiled: April 30, 2019Publication date: November 25, 2021Inventors: Pu SUN, Shouhua LV, Zhen WANG
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Patent number: 11158799Abstract: A mask assembly and a method of patterning a semiconductor film using the mask assembly. A first mask comprises a plurality of first light shielding regions, a plurality of first light transmissive regions, and at least one first light shielding island; a boundary of a first light shielding island is not connected to a boundary of the first mask; a second mask comprises a plurality of second light shielding regions, a plurality of second light transmissive regions, and at least one second light shielding island; a boundary of the second light shielding island is not connected to a boundary of the second mask; the first light shielding region and the second light shielding region are complementarily arranged, the first light transmissive region and the second light transmissive region are complementarily disposed.Type: GrantFiled: January 11, 2019Date of Patent: October 26, 2021Inventor: Pu Sun
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Publication number: 20210184125Abstract: A mask assembly and a method of patterning a semiconductor film using the mask assembly. A first mask comprises a plurality of first light shielding regions, a plurality of first light transmissive regions, and at least one first light shielding island; a boundary of a first light shielding island is not connected to a boundary of the first mask; a second mask comprises a plurality of second light shielding regions, a plurality of second light transmissive regions, and at least one second light shielding island; a boundary of the second light shielding island is not connected to a boundary of the second mask; the first light shielding region and the second light shielding region are complementarily arranged, the first light transmissive region and the second light transmissive region are complementarily disposed.Type: ApplicationFiled: January 11, 2019Publication date: June 17, 2021Applicant: Wuhan China Star Optoelectronics Semiconductort Display Technology Co., Ltd.Inventor: Pu SUN
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Publication number: 20210147525Abstract: Pathogenic blood vessels are blood vessels that are not involved in the vascularization of normal organs but are in the pathogenic tissues such as the new blood vessels that drive vision diseases or the blood vessels in tumors that tumors depend on to survive. The current disclosure provides an advancement over typical anti-angiogenic strategies that target the generation of new blood vessels by providing compositions and methods that can selectively target and kill existing pathogenic blood vessels. The conventional antiangiogenic drugs or factors inhibit angiogenesis (the growth of new blood vessels), but cannot effectively kill existing pathogenic blood vessels. Agents, including small molecule compounds and antibodies, have been identified that bind to and activate PLXDC1 and PLXDC2 proteins, leading to effective killing of the endothelial cells in pathogenic blood vessels in vision diseases and in tumors that express these proteins.Type: ApplicationFiled: October 16, 2020Publication date: May 20, 2021Inventors: HUI SUN, Adrian Chichuen Au, Guo Cheng, Pu Sun
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Publication number: 20210147385Abstract: The disclosure provides compounds, and compositions, including pharmaceutical compositions, kits that include the compounds, and methods of using (or administering) and making the compounds. The disclosure further provides compounds or compositions thereof for use in a method of modulating PLXDC1 (TEM7) and/or PLXDC2 or killing pathogenic blood vessles. The disclosure further provides compounds or compositions thereof for use in a method of treating a disease, disorder, or condition that is mediated, at least in part, by PEDF receptors or by angiogenesis.Type: ApplicationFiled: October 16, 2020Publication date: May 20, 2021Inventors: HUI SUN, Pu Sun, Guo Cheng, Adrian Chichuen Au, Ming Zhong
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Patent number: 10961616Abstract: This disclosure relates to the field of display fabrication technologies, and discloses a fine mask support frame, a fine mask, and a method for fabricating the same. The fine mask support frame includes: a plurality of bezels surrounding a mask area, wherein adjustment openings are arranged on at least one pair of bezels arranged opposite to each other, and at least one adjustment piece is arranged on each of the adjustment openings, wherein the adjustment piece is configured to adjust a shape of a corresponding adjustment opening to thereby adjust deformation of the mask area.Type: GrantFiled: January 5, 2018Date of Patent: March 30, 2021Assignees: BOE TECHNOLOGY GROUP CO., LTD., ORDOS YUANSHENG OPTOELECTRONICS CO., LTD.Inventors: Zhiming Lin, Baojun Li, Jian Zhang, Pu Sun, Chun Chieh Huang
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Patent number: 10766949Abstract: The present invention relates to a method for preparing a whole bovine-derived broadly neutralizing antibody against serotype O foot-and-mouth disease virus, and belongs to the technical field of antibody preparation. The method includes the following steps: 1) conducting the immunization on the cattle; 2) screening for the serotype O foot-and-mouth disease virus antigen-specific single B cells; 3) amplifying variable region genes of the heavy and light chains; 4) acquiring constant region sequences of the heavy and light chains; 5) preparing a full-length heavy chain vector; 6) co-transfecting a cell, taking the supernatant of cell culture, and purifying. The method utilizes different foot-and-mouth disease virus strains to infect cattle and obtains a neutralizing antibody capable of neutralizing three topotypes of serotype O FMDVs by screening, and thus can obtain a whole bovine-derived broadly neutralizing monoclonal antibody.Type: GrantFiled: August 14, 2019Date of Patent: September 8, 2020Assignee: Lanzhour Veterinary Research Institute, Chinese Academy of Agricultural SciencesInventors: Kun Li, Zengjun Lu, Zaixin Liu, Yimei Cao, Huifang Bao, Yingli Chen, Sheng Wang, Pinghua Li, Pu Sun, Xingwen Bai, Dong Li
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Publication number: 20200055925Abstract: The present invention relates to a method for preparing a whole bovine-derived broadly neutralizing antibody against serotype O foot-and-mouth disease virus, and belongs to the technical field of antibody preparation.Type: ApplicationFiled: August 14, 2019Publication date: February 20, 2020Inventors: Kun Li, Zengjun Lu, Zaixin Liu, Yimei Cao, Huifang Bao, Yingli Chen, Sheng Wang, Pinghua Li, Pu Sun, Xingwen Bai, Dong Li
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Publication number: 20190177831Abstract: This disclosure relates to the field of display fabrication technologies, and discloses a fine mask support frame, a fine mask, and a method for fabricating the same so as to improve the positional precision of opening areas of the mask to thereby further improve the precision of the mask. The fine mask support frame includes: a plurality of bezels surrounding a mask area, wherein adjustment openings are arranged on at least one pair of bezels arranged opposite to each other, and at least one adjustment piece is arranged on each of the adjustment openings, wherein the adjustment piece is configured to adjust a shape of a corresponding adjustment opening to thereby adjust deformation of the mask area.Type: ApplicationFiled: January 5, 2018Publication date: June 13, 2019Inventors: Zhiming Lin, Baojun Li, Jian Zhang, Pu Sun, Chun Chieh Huang
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Patent number: 10233811Abstract: An engine control system includes a selective catalyst reduction (SCR) device that reduces nitrogen oxide (NOx) in exhaust gas in the presence of the reductant. A particulate filter (PF) is disposed downstream from the SCR device to collect particulate matter from the exhaust gas stream. The engine control system further includes an electronic hardware that calculates a particulate matter load value indicating an amount of particulate matter collected in the PF, and calculate a CCB value that compensates for pressure differential variations across the PF. The controller further calculates a CCB correction value that modifies the CCB value and compensates for an amount of reductant that slips from the SCR device and induces the pressure differential variations. In this manner, the electronic hardware controller can control a regeneration system to increase the temperature of the PF to burn off particulate matter from the PF based on the modified CCB value.Type: GrantFiled: March 27, 2017Date of Patent: March 19, 2019Assignee: GM GLOBAL TECHNOLOGY OPERATIONS LLCInventors: Michael A. Smith, Pu Sun, Harish Kohli
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Publication number: 20180274422Abstract: An engine control system includes a selective catalyst reduction (SCR) device that reduces nitrogen oxide (NOx) in exhaust gas in the presence of the reductant. A particulate filter (PF) is disposed downstream from the SCR device to collect particulate matter from the exhaust gas stream. The engine control system further includes an electronic hardware that calculates a particulate matter load value indicating an amount of particulate matter collected in the PF, and calculate a CCB value that compensates for pressure differential variations across the PF. The controller further calculates a CCB correction value that modifies the CCB value and compensates for an amount of reductant that slips from the SCR device and induces the pressure differential variations. In this manner, the electronic hardware controller can control a regeneration system to increase the temperature of the PF to burn off particulate matter from the PF based on the modified CCB value.Type: ApplicationFiled: March 27, 2017Publication date: September 27, 2018Inventors: Michael A. Smith, Pu Sun, Harish Kohli
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Publication number: 20180231540Abstract: A reagent kit used for detecting gastrin-17, a preparation method, and a detection method for the reagent kit. The reagent kit comprises component A and component B, wherein component A is a first anti-gastrin-17 antibody marked with a trace marker or coated on magnetic spheres, and component B is a second gastrin-17 antibody or gastrin-17 coated on magnetic spheres or marked with a trace marker. Either one of component A and component B is marked with the trace marker, and the other one is coated on the magnetic spheres. The first gastrin-17 antibody and gastrin-17 binding site is different from the second gastrin-17 antibody and gastrin-17 binding site. The method using a double antibody sandwich method or a competition method to detect gastrin-17 accurately and sensitively measures the amount of gastrin-17 in a sample.Type: ApplicationFiled: February 10, 2017Publication date: August 16, 2018Inventors: Wei RAO, Pu SUN, Yunxuan LI, Wang LIU, Yali YANG, Jinyun YUAN, Tinghua LI
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Publication number: 20180216220Abstract: A mask includes a plurality of mask strips and a mounting frame, the plurality of mask strips are mounted on a mounting frame after being stretched. Each mask strip includes a plurality of mask units. Each mask unit includes an effective opening region and two vacant regions. Mask openings are disposed in the effective opening region. The two vacant regions are respectively provided on both sides of the effective opening region perpendicular to a stretching direction and close to the effective opening region. Vacant openings are disposed in the vacant regions. Wherein the contour shape of each mask opening is different from that of each vacant opening and the stress generated by the mask openings and the stress generated by the vacant openings in a stretching process can be mutually compensated.Type: ApplicationFiled: February 3, 2017Publication date: August 2, 2018Inventors: Shouhua LV, Pu SUN