Patents by Inventor Pubudu M. Peiris

Pubudu M. Peiris has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MESOPOROUS SILICA NANOPARTICLES FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS
    Publication number: 20230016609
    Abstract: A system for delivering a therapeutic agent to cell or tissue of a subject includes a mesoporous silica iron oxide nanoparticle with one or more therapeutic agents that are contained in a mesoporous silica layer of the nanoparticle and a remote radiofrequency (RF) energy source for applying RF energy to the nanoparticle effective to release the one or more therapeutic agents from the nanoparticle by mechanical tumbling and/or vibration of the nanoparticle, wherein release of the one or more therapeutic agents not caused by a hyperthermic response of the nanoparticle to the RF energy.
    Type: Application
    Filed: March 1, 2022
    Publication date: January 19, 2023
    Inventors: Efstathios Karathanasis, Watuthentrige Pubudu M. Peiris, Vindya Perera, Lisa Bauer
  • Mesoporous silica nanoparticles for diagnostic and therapeutic applications
    Patent number: 11260127
    Abstract: A system for delivering a therapeutic agent to cell or tissue of a subject includes a mesoporous silica iron oxide nanoparticle with one or more therapeutic agents that are contained in a mesoporous silica layer of the nanoparticle and a remote radiofrequency (RF) energy source for applying RF energy to the nanoparticle effective to release the one or more therapeutic agents from the nanoparticle by mechanical tumbling and/or vibration of the nanoparticle, wherein release of the one or more therapeutic agents not caused by a hyperthermic response of the nanoparticle to the RF energy.
    Type: Grant
    Filed: October 17, 2018
    Date of Patent: March 1, 2022
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Efstathios Karathanasis, Watuthentrige Pubudu M. Peiris, Vindya Perera, Lisa Bauer
  • Multi-component nanochains
    Patent number: 11065202
    Abstract: A multi-component nanochain for use in diagnostic and therapeutic applications includes at least three nanoparticles linked together to form the nanochain. At least one nanoparticle of the nanochain has an asymmetric surface chemistry defined by asymmetrically disposed first linkers and second linkers. The nanoparticles are linked to form the nanochain by linking first linkers and/or second linkers disposed on separate nanoparticles.
    Type: Grant
    Filed: December 4, 2018
    Date of Patent: July 20, 2021
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Efstathios Karathanasis, Watuthantrige Pubudu M Peiris, Mark Griswold
  • MULTI-COMPONENT NANOCHAINS
    Publication number: 20210186875
    Abstract: A multi-component nanochain for use in diagnostic and therapeutic applications includes at least three nanoparticles linked together to form the nanochain. At least one nanoparticle of the nanochain has an asymmetric surface chemistry defined by asymmetrically disposed first linkers and second linkers. The nanoparticles are linked to form the nanochain by linking first linkers and/or second linkers disposed on separate nanoparticles.
    Type: Application
    Filed: December 4, 2018
    Publication date: June 24, 2021
    Inventors: Efstathios Karathanasis, Watuthantrige Pubudu M Peiris, Mark Griswold
  • Multi-component nanoconstructs
    Patent number: 10729652
    Abstract: A multi-component nanoconstruct for use in diagnostic and therapeutic applications includes at least three nanoparticles linked together to form the nanochain. The nanoparticles are linked to form the nanochain by linking first linkers and/or second linkers disposed on separate nanoparticles.
    Type: Grant
    Filed: March 15, 2018
    Date of Patent: August 4, 2020
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Efstathios Karathanasis, Watuthentrige Pubudu M. Peiris, Elizabeth Doolittle
  • MULTI-COMPONENT NANOCHAINS
    Publication number: 20190307687
    Abstract: A multi-component nanochain for use in diagnostic and therapeutic applications includes at least three nanoparticles linked together to form the nanochain. At least one nanoparticle of the nanochain has an asymmetric surface chemistry defined by asymmetrically disposed first linkers and second linkers. The nanoparticles are linked to form the nanochain by linking first linkers and/or second linkers disposed on separate nanoparticles.
    Type: Application
    Filed: December 4, 2018
    Publication date: October 10, 2019
    Inventors: Efstathios Karathanasis, Watuthantrige Pubudu M Peiris, Mark Griswold
  • Multi-component nanochains
    Patent number: 10143653
    Abstract: A multi-component nanochain for use in diagnostic and therapeutic applications includes at least three nanoparticles linked together to form the nanochain. At least one nanoparticle of the nanochain has an asymmetric surface chemistry defined by asymmetrically disposed first linkers and second linkers. The nanoparticles are linked to form the nanochain by linking first linkers and/or second linkers disposed on separate nanoparticles.
    Type: Grant
    Filed: September 12, 2016
    Date of Patent: December 4, 2018
    Assignee: Case Western Reserve University
    Inventors: Efstathios Karathanasis, Watuthantrige Pubudu M Peiris, Mark Griswold
  • MULTI-COMPONENT NANOCONSTRUCTS
    Publication number: 20180263910
    Abstract: A multi-component nanoconstruct for use in diagnostic and therapeutic applications includes at least three nanoparticles linked together to form the nanochain. The nanoparticles are linked to form the nanochain by linking first linkers and/or second linkers disposed on separate nanoparticles.
    Type: Application
    Filed: March 15, 2018
    Publication date: September 20, 2018
    Inventors: Efstathios Karathanasis, Pubudu M. Peiris Watuthentrige, Vindya Perera, Prabhani Atukorale
  • MULTI-COMPONENT NANOCHAINS
    Publication number: 20170216206
    Abstract: A multi-component nanochain for use in diagnostic and therapeutic applications includes at least three nanoparticles linked together to form the nanochain. At least one nanoparticle of the nanochain has an asymmetric surface chemistry defined by asymmetrically disposed first linkers and second linkers. The nanoparticles are linked to form the nanochain by linking first linkers and/or second linkers disposed on separate nanoparticles.
    Type: Application
    Filed: September 12, 2016
    Publication date: August 3, 2017
    Inventors: Efstathios Karathanasis, Watuthantrige Pubudu M Peiris, Mark Griswold
  • Multi-component nanochains
    Patent number: 9439966
    Abstract: A multi-component nanochain for use in diagnostic and therapeutic applications includes at least three nanoparticles linked together to form the nanochain. At least one nanoparticle of the nanochain has an asymmetric surface chemistry defined by asymmetrically disposed first linkers and second linkers. The nanoparticles are linked to form the nanochain by linking first linkers and/or second linkers disposed on separate nanoparticles.
    Type: Grant
    Filed: October 12, 2012
    Date of Patent: September 13, 2016
    Assignee: Case Western Reserve University
    Inventors: Efstathios Karathanasis, Watuthantrige Pubudu M. Peiris, Mark Griswold
  • MULTI-COMPONENT NANOCHAINS
    Publication number: 20140248339
    Abstract: A multi-component nanochain for use in diagnostic and therapeutic applications includes at least three nanoparticles linked together to form the nanochain. At least one nanoparticle of the nanochain has an asymmetric surface chemistry defined by asymmetrically disposed first linkers and second linkers. The nanoparticles are linked to form the nanochain by linking first linkers and/or second linkers disposed on separate nanoparticles.
    Type: Application
    Filed: October 12, 2012
    Publication date: September 4, 2014
    Applicant: Case Western Reserve University
    Inventors: Efstathios Karathanasis, Pubudu M. Peiris, Mark Griswold