Patents by Inventor Pulin Li

Pulin Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for enhancing hematopoietic stem/progenitor cell engraftment
    Patent number: 10159697
    Abstract: Described herein are methods for enhancing engraftment of hematopoietic stem and progenitor cells using farnesyl compounds identified using a zebrafish model of hematopoietic cell engraftment. The compounds can be used to treat hematopoietic stem cells ex vivo prior to transplantation of the cells. Alternatively, the compounds can be administered to an individual undergoing cell transplantation.
    Type: Grant
    Filed: July 17, 2017
    Date of Patent: December 25, 2018
    Assignee: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Leonard I. Zon, Pulin Li
  • Methods for enhancing hematopoietic stem/progenitor cell engraftment
    Patent number: 10092599
    Abstract: Described herein are methods for enhancing engraftment of hematopoietic stem and progenitor cells using compounds identified using a zebrafish model of hematopoietic cell engraftment. The compounds can be used to treat hematopoietic stem cells ex vivo prior to transplantation of the cells. Alternatively, the compounds can be administered to an individual undergoing cell transplantation.
    Type: Grant
    Filed: May 7, 2015
    Date of Patent: October 9, 2018
    Assignee: Children's Medical Center Corporation
    Inventors: Leonard I. Zon, Pulin Li
  • METHODS FOR ENHANCING HEMATOPOIETIC STEM/PROGENITOR CELL ENGRAFTMENT
    Publication number: 20170333483
    Abstract: Described herein are methods for enhancing engraftment of hematopoietic stem and progenitor cells using farnesyl compounds identified using a zebrafish model of hematopoietic cell engraftment. The compounds can be used to treat hematopoietic stem cells ex vivo prior to transplantation of the cells. Alternatively, the compounds can be administered to an individual undergoing cell transplantation.
    Type: Application
    Filed: July 17, 2017
    Publication date: November 23, 2017
    Inventors: Leonard I. Zon, Pulin Li
  • Methods for enhancing hematopoietic stem/progenitor cell engraftment
    Patent number: 9737567
    Abstract: Described herein are methods for enhancing engraftment of hematopoietic stem and progenitor cells using farnesyl compounds identified using a zebrafish model of hematopoietic cell engraftment. The compounds can be used to treat hematopoietic stem cells ex vivo prior to transplantation of the cells. Alternatively, the compounds can be administered to an individual undergoing cell transplantation.
    Type: Grant
    Filed: April 21, 2015
    Date of Patent: August 22, 2017
    Assignee: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Leonard I. Zon, Pulin Li
  • METHODS FOR ENHANCING HEMATOPOIETIC STEM/PROGENITOR CELL ENGRAFTMENT
    Publication number: 20150272996
    Abstract: Described herein are methods for enhancing engraftment of hematopoietic stem and progenitor cells using farnesyl compounds identified using a zebrafish model of hematopoietic cell engraftment. The compounds can be used to treat hematopoietic stem cells ex vivo prior to transplantation of the cells. Alternatively, the compounds can be administered to an individual undergoing cell transplantation.
    Type: Application
    Filed: April 21, 2015
    Publication date: October 1, 2015
    Inventors: Leonard I. Zon, Pulin Li
  • METHODS FOR ENHANCING HEMATOPOIETIC STEM/PROGENITOR CELL ENGRAFTMENT
    Publication number: 20150246075
    Abstract: Described herein are methods for enhancing engraftment of hematopoietic stem and progenitor cells using compounds identified using a zebrafish model of hematopoietic cell engraftment. The compounds can be used to treat hematopoietic stem cells ex vivo prior to transplantation of the cells. Alternatively, the compounds can be administered to an individual undergoing cell transplantation.
    Type: Application
    Filed: May 7, 2015
    Publication date: September 3, 2015
    Inventors: Leonard I. Zon, Pulin Li
  • Methods for enhancing hematopoietic stem/progenitor cell engraftment
    Patent number: 9056085
    Abstract: Described herein are methods for enhancing engraftment of hematopoietic stem and progenitor cells using compounds identified using a zebrafish model of hematopoietic cell engraftment. The compounds can be used to treat hematopoietic stem cells ex vivo prior to transplantation of the cells. Alternatively, the compounds can be administered to an individual undergoing cell transplantation.
    Type: Grant
    Filed: February 3, 2010
    Date of Patent: June 16, 2015
    Assignee: Children's Medical Center Corporation
    Inventors: Leonard I. Zon, Pulin Li
  • Methods for enhancing hematopoietic stem/progenitor cell engraftment
    Patent number: 9051548
    Abstract: Described herein are methods for enhancing engraftment of hematopoietic stem and progenitor cells using farnesyl compounds identified using a zebrafish model of hematopoietic cell engraftment. The compounds can be used to treat hematopoietic stem cells ex vivo prior to transplantation of the cells. Alternatively, the compounds can be administered to an individual undergoing cell transplantation.
    Type: Grant
    Filed: February 3, 2010
    Date of Patent: June 9, 2015
    Assignee: Children's Medical Center Corporation
    Inventors: Leonard I. Zon, Pulin Li
  • METHODS FOR ENHANCING HEMATOPOIETIC STEM/PROGENITOR CELL ENGRAFTMENT
    Publication number: 20110305676
    Abstract: Described herein are methods for enhancing engraftment of hematopoietic stem and progenitor cells using compounds identified using a zebrafish model of hematopoietic cell engraftment. The compounds can be used to treat hematopoietic stem cells ex vivo prior to transplantation of the cells. Alternatively, the compounds can be administered to an individual undergoing cell transplantation.
    Type: Application
    Filed: February 3, 2010
    Publication date: December 15, 2011
    Applicant: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Leonard I. Zon, Pulin Li
  • METHODS FOR ENHANCING HEMATOPOIETIC STEM/PROGENITOR CELL ENGRAFTMENT
    Publication number: 20110293582
    Abstract: Described herein are methods for enhancing engraftment of hematopoietic stem and progenitor cells using farnesyl compounds identified using a zebrafish model of hematopoietic cell engraftment. The compounds can be used to treat hematopoietic stem cells ex vivo prior to transplantation of the cells. Alternatively, the compounds can be administered to an individual undergoing cell transplantation.
    Type: Application
    Filed: February 3, 2010
    Publication date: December 1, 2011
    Applicant: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Leonard I. Zon, Pulin Li