Patents by Inventor Pulin Wang
Pulin Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11970512Abstract: Provided are certain derivatives of amphotericin B (AmB) characterized by reduced toxicity and retained anti-fungal activity. Certain of the derivatives are C16 urea derivatives of AmB. Certain of the derivatives are C3, C5, C8, C9, C11, C13, or C15 deoxy derivatives of AmB. Certain of the derivatives include C3? or C4? modifications of the mycosamine appendage of AmB. Also provided are methods of making AmB derivatives of the invention, pharmaceutical compositions comprising AmB derivatives of the invention, and methods of use of AmB derivatives of the invention.Type: GrantFiled: September 2, 2021Date of Patent: April 30, 2024Assignee: The Board of Trustees of the University of IllinoisInventors: Martin D. Burke, Stephen Davis, Brice E. Uno, Justin Struble, Ian Dailey, Kaitlyn C. Gray, David M. Knapp, Pulin Wang, Nagarjuna Palyam
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Patent number: 11793439Abstract: Epidermal electronics are non-invasive and non-obstructive skin mounted sensors with mechanical properties matching human epidermis. Their manufacturing process includes photolithography and dry and wet etching within cleanroom facilities. The high cost of manpower, materials, photo masks, and facilities greatly hinders the commercialization potential of disposable epidermal electronics. In contrast, an embodiment of the invention includes a low cost, high throughput, bench top “cut-and-paste” method to complete the freeform manufacture of epidermal sensor system (ESS) in minutes. This versatile method works for many types of thin metal and polymeric sheets and is compatible with many tattoo adhesives or medical tapes. The resultant ESS is highly multimaterial and multifunctional and may measure ECG, EMG, skin temperature, skin hydration, as well as respiratory rate.Type: GrantFiled: April 26, 2022Date of Patent: October 24, 2023Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Nanshu Lu, Shixuan Yang, Pulin Wang
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Publication number: 20220249000Abstract: Epidermal electronics are non-invasive and non-obstructive skin mounted sensors with mechanical properties matching human epidermis. Their manufacturing process includes photolithography and dry and wet etching within cleanroom facilities. The high cost of manpower, materials, photo masks, and facilities greatly hinders the commercialization potential of disposable epidermal electronics. In contrast, an embodiment of the invention includes a low cost, high throughput, bench top “cut-and-paste” method to complete the freeform manufacture of epidermal sensor system (ESS) in minutes. This versatile method works for many types of thin metal and polymeric sheets and is compatible with many tattoo adhesives or medical tapes. The resultant ESS is highly multimaterial and multifunctional and may measure ECG, EMG, skin temperature, skin hydration, as well as respiratory rate.Type: ApplicationFiled: April 26, 2022Publication date: August 11, 2022Inventors: Nanshu Lu, Shixuan Yang, Pulin Wang
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Patent number: 11344237Abstract: Epidermal electronics are sensors with mechanical properties matching human epidermis. Their manufacturing process includes photolithography and dry and wet etching within cleanroom facilities. The high cost of manpower, materials, photo masks, and facilities greatly hinders the commercialization potential of disposable epidermal electronics. In contrast, an embodiment of the invention includes a low cost, high throughput, bench top “cut-and-paste” method to complete the freeform manufacture of epidermal sensor system (ESS) in minutes. This versatile method works for many types of thin metal and polymeric sheets and is compatible with many tattoo adhesives or medical tapes. The resultant ESS is highly multimaterial and multifunctional and may measure ECG, EMG, skin temperature, skin hydration, as well as respiratory rate. Also, a stretchable planar coil made of serpentine ribbons can be used as a wireless strain gauge and/or a near field communication (NFC) antenna. Other embodiments are described herein.Type: GrantFiled: November 27, 2019Date of Patent: May 31, 2022Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Nanshu Lu, Shixuan Yang, Pulin Wang
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Patent number: 11311223Abstract: Epidermal electronics are sensors with mechanical properties matching human epidermis. Their manufacturing process includes photolithography and dry and wet etching within cleanroom facilities. The high cost of manpower, materials, photo masks, and facilities greatly hinders the commercialization potential of disposable epidermal electronics. In contrast, an embodiment of the invention includes a low cost, high throughput, bench top “cut-and-paste” method to complete the freeform manufacture of epidermal sensor system (ESS) in minutes. This versatile method works for many types of thin metal and polymeric sheets and is compatible with many tattoo adhesives or medical tapes. The resultant ESS is highly multimaterial and multifunctional and may measure ECG, EMG, skin temperature, skin hydration, as well as respiratory rate. Also, a stretchable planar coil made of serpentine ribbons can be used as a wireless strain gauge and/or a near field communication (NFC) antenna. Other embodiments are described herein.Type: GrantFiled: November 27, 2019Date of Patent: April 26, 2022Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Nanshu Lu, Shixuan Yang, Pulin Wang
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Publication number: 20220056066Abstract: Provided are certain derivatives of amphotericin B (AmB) characterized by reduced toxicity and retained anti-fungal activity. Certain of the derivatives are C16 urea derivatives of AmB. Certain of the derivatives are C3, C5, C8, C9, C11, C13, or C15 deoxy derivatives of AmB. Certain of the derivatives include C3? or C4? modifications of the mycosamine appendage of AmB. Also provided are methods of making AmB derivatives of the invention, pharmaceutical compositions comprising AmB derivatives of the invention, and methods of use of AmB derivatives of the invention.Type: ApplicationFiled: September 2, 2021Publication date: February 24, 2022Inventors: Martin D. Burke, Stephen Davis, Brice E. Uno, Justin Struble, Ian Dailey, Kaitlyn C. Gray, David M. Knapp, Pulin Wang, Nagarjuna Palyam
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Patent number: 11216629Abstract: The present specification provides a two-dimensional code identification method and device, and a two-dimensional code positioning and identification model establishment method and device. The two-dimensional code identification method includes: obtaining a to-be-identified two-dimensional code, and performing global feature positioning detection on the to-be-identified two-dimensional code by using a pre-established two-dimensional code positioning and identification model; performing focus adjustment, based on a predetermined image resolution, on the to-be-identified two-dimensional code on which positioning detection is performed; and decoding the to-be-identified two-dimensional code on which focus adjustment is performed. The present specification can improve the identification accuracy of two-dimensional codes shot in complex scenarios.Type: GrantFiled: March 22, 2021Date of Patent: January 4, 2022Assignee: Advanced New Technologies Co., Ltd.Inventors: Mingjie Liang, Jiada Chen, Shuang Chen, Pulin Wang
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Patent number: 11117920Abstract: Provided are certain derivatives of amphotericin B (AmB) characterized by reduced toxicity and retained anti-fungal activity. Certain of the derivatives are C16 urea derivatives of AmB. Certain of the derivatives are C3, C5, C8, C9, C11, C13, or C15 deoxy derivatives of AmB. Certain of the derivatives include C3? or C4? modifications of the mycosamine appendage of AmB. Also provided are methods of making AmB derivatives of the invention, pharmaceutical compositions comprising AmB derivatives of the invention, and methods of use of AmB derivatives of the invention.Type: GrantFiled: June 17, 2019Date of Patent: September 14, 2021Assignee: The Board of Trustees of the University of IllinoisInventors: Martin D. Burke, Stephen Davis, Brice E. Uno, Justin Struble, Ian Dailey, Kaitlyn C. Gray, David M. Knapp, Pulin Wang, Nagarjuna Palyam
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Patent number: 11109029Abstract: The disclosure discloses a video enhancement method and device, and belongs to the field of image processing. The method includes that: each frame in a video is sequentially acquired; and for each current frame, attribute information reflecting a moving state or luminance is determined, a preset mapping relationship is searched to obtain a control parameter corresponding to the attribute information, and video enhancement operation is executed on the current frame by using the control parameter. The device includes: an acquisition module and an enhancement module. By the disclosure, the problem of processing inflexibility caused by execution of the same enhancement over each frame in the video is solved, each frame in the video may be differentially enhanced, frame-based video enhancement is implemented, a video enhancement effect is effectively improved, and quality of the video is improved.Type: GrantFiled: July 2, 2019Date of Patent: August 31, 2021Assignee: TENCENT TECHNOLOGY (SHENZHEN) COMPANY LIMITEDInventors: Kai Li, Pulin Wang, Xiaocui Ji
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Publication number: 20210209323Abstract: The present specification provides a two-dimensional code identification method and device, and a two-dimensional code positioning and identification model establishment method and device. The two-dimensional code identification method includes: obtaining a to-be-identified two-dimensional code, and performing global feature positioning detection on the to-be-identified two-dimensional code by using a pre-established two-dimensional code positioning and identification model; performing focus adjustment, based on a predetermined image resolution, on the to-be-identified two-dimensional code on which positioning detection is performed; and decoding the to-be-identified two-dimensional code on which focus adjustment is performed. The present specification can improve the identification accuracy of two-dimensional codes shot in complex scenarios.Type: ApplicationFiled: March 22, 2021Publication date: July 8, 2021Applicant: Advanced New Technologies Co., Ltd.Inventors: Mingjie Liang, Jiada Chen, Shuang Chen, Pulin Wang
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Patent number: 11028114Abstract: Provided are certain derivatives of amphotericin B (AmB) characterized by reduced toxicity and retained anti-fungal activity. Certain of the derivatives are C16 urea derivatives of AmB. Certain of the derivatives are C3, C5, C8, C9, C11, C13, or C15 deoxy derivatives of AmB. Certain of the derivatives include C3? or C4? modifications of the mycosamine appendage of AmB. Also provided are methods of making AmB derivatives of the invention, pharmaceutical compositions comprising AmB derivatives of the invention, and methods of use of AmB derivatives of the invention.Type: GrantFiled: August 2, 2019Date of Patent: June 8, 2021Assignee: The Board of Trustees of the University of IllinoisInventors: Martin D. Burke, Stephen Davis, Brice E. Uno, Justin Struble, Ian Dailey, Kaitlyn C. Gray, David M. Knapp, Pulin Wang, Nagarjuna Palyam
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Patent number: 10956696Abstract: The present specification provides a two-dimensional code identification method and device, and a two-dimensional code positioning and identification model establishment method and device. The two-dimensional code identification method includes: obtaining a to-be-identified two-dimensional code, and performing global feature positioning detection on the to-be-identified two-dimensional code by using a pre-established two-dimensional code positioning and identification model; performing focus adjustment, based on a predetermined image resolution, on the to-be-identified two-dimensional code on which positioning detection is performed; and decoding the to-be-identified two-dimensional code on which focus adjustment is performed. The present specification can improve the identification accuracy of two-dimensional codes shot in complex scenarios.Type: GrantFiled: March 4, 2020Date of Patent: March 23, 2021Assignee: Advanced New Technologies Co., Ltd.Inventors: Mingjie Liang, Jiada Chen, Shuang Chen, Pulin Wang
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Publication number: 20200380227Abstract: The present specification provides a two-dimensional code identification method and device, and a two-dimensional code positioning and identification model establishment method and device. The two-dimensional code identification method includes: obtaining a to-be-identified two-dimensional code, and performing global feature positioning detection on the to-be-identified two-dimensional code by using a pre-established two-dimensional code positioning and identification model; performing focus adjustment, based on a predetermined image resolution, on the to-be-identified two-dimensional code on which positioning detection is performed; and decoding the to-be-identified two-dimensional code on which focus adjustment is performed. The present specification can improve the identification accuracy of two-dimensional codes shot in complex scenarios.Type: ApplicationFiled: March 4, 2020Publication date: December 3, 2020Applicant: Alibaba Group Holding LimitedInventors: Mingjie Liang, Jiada Chen, Shuang Chen, Pulin Wang
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Patent number: 10781609Abstract: An electronic door opening/closing apparatus and an electronic door opening/closing detection method, apparatus, and device are disclosed. The electronic door opening/closing apparatus includes: an electronic lock, disposed at a side-hinged door and configured to limit a turn of a door panel of the side-hinged door when the electronic lock is locked; a turning detector, disposed at the side-hinged door and configured to detect a turning parameter of the door panel of the side-hinged door to generate a turning parameter signal; a position detector, disposed at the side-hinged door and configured to generate a door state signal based on a position-approaching condition; and a main controller, configured to determine an open or closed state of the side-hinged door. The turning parameter signal is combined with the door state signal to accurately determine the open or closed state of the side-hinged door, and to effectively prevent malicious lock deception.Type: GrantFiled: March 18, 2020Date of Patent: September 22, 2020Assignee: Alibaba Group Holding LimitedInventors: Wenzhou Cai, Pulin Wang
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Publication number: 20200232253Abstract: An electronic door opening/closing apparatus and an electronic door opening/closing detection method, apparatus, and device are disclosed. The electronic door opening/closing apparatus includes: an electronic lock, disposed at a side-hinged door and configured to limit a turn of a door panel of the side-hinged door when the electronic lock is locked; a turning detector, disposed at the side-hinged door and configured to detect a turning parameter of the door panel of the side-hinged door to generate a turning parameter signal; a position detector, disposed at the side-hinged door and configured to generate a door state signal based on a position-approaching condition; and a main controller, configured to determine an open or closed state of the side-hinged door. The turning parameter signal is combined with the door state signal to accurately determine the open or closed state of the side-hinged door, and to effectively prevent malicious lock deception.Type: ApplicationFiled: March 18, 2020Publication date: July 23, 2020Inventors: Wenzhou CAI, Pulin WANG
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Publication number: 20200107740Abstract: Epidermal electronics are sensors with mechanical properties matching human epidermis. Their manufacturing process includes photolithography and dry and wet etching within cleanroom facilities. The high cost of manpower, materials, photo masks, and facilities greatly hinders the commercialization potential of disposable epidermal electronics. In contrast, an embodiment of the invention includes a low cost, high throughput, bench top “cut-and-paste” method to complete the freeform manufacture of epidermal sensor system (ESS) in minutes. This versatile method works for many types of thin metal and polymeric sheets and is compatible with many tattoo adhesives or medical tapes. The resultant ESS is highly multimaterial and multifunctional and may measure ECG, EMG, skin temperature, skin hydration, as well as respiratory rate. Also, a stretchable planar coil made of serpentine ribbons can be used as a wireless strain gauge and/or a near field communication (NFC) antenna. Other embodiments are described herein.Type: ApplicationFiled: November 27, 2019Publication date: April 9, 2020Inventors: Nanshu Lu, Shixuan Yang, Pulin Wang
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Publication number: 20200085336Abstract: A dual-mode epidermal sensor/electrode that, when worn on a human chest, is capable of synchronously/continuously monitoring electrical activity and mechano-acoustic activity of a cardiovascular system. The dual-mode epidermal sensor/electrode consists of a pair of stretchable electrocardiogram (ECG) electrodes made out of filamentary serpentine gold nano-membranes and a stretchable seismocardiogram (SCG) sensor comprising a filamentary serpentine PVDF. The dual-mode epidermal sensor/electrode is light, thin, flexible, and requires no operational power. The sensor can be laminated conformably and unobtrusively on a human chest to provide high fidelity ECG measurements and SCG measurements, and an estimated beat-to-beat blood pressure (BP). The dual-mode epidermal sensor is fabricated using a cost-effective, cut-and-paste method of construction.Type: ApplicationFiled: May 22, 2018Publication date: March 19, 2020Inventors: Nanshu LU, Taewoo HA, Pulin WANG
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Publication number: 20200002368Abstract: Provided are certain derivatives of amphotericin B (AmB) characterized by reduced toxicity and retained anti-fungal activity. Certain of the derivatives are C16 urea derivatives of AmB. Certain of the derivatives are C3, C5, C8, C9, C11, C13, or C15 deoxy derivatives of AmB. Certain of the derivatives include C3? or C4? modifications of the mycosamine appendage of AmB. Also provided are methods of making AmB derivatives of the invention, pharmaceutical compositions comprising AmB derivatives of the invention, and methods of use of AmB derivatives of the invention.Type: ApplicationFiled: August 2, 2019Publication date: January 2, 2020Inventors: Martin D. Burke, Stephen Davis, Brice E. Uno, Justin Struble, Ian Dailey, Kaitlyn C. Gray, David M. Knapp, Pulin Wang, Nagarjuna Palyam
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Patent number: 10492703Abstract: Epidermal electronics are sensors with mechanical properties matching human epidermis. Their manufacturing process includes photolithography and dry and wet etching within cleanroom facilities. The high cost of manpower, materials, photo masks, and facilities greatly hinders the commercialization potential of disposable epidermal electronics. In contrast, an embodiment of the invention includes a low cost, high throughput, bench top “cut-and-paste” method to complete the freeform manufacture of epidermal sensor system (ESS) in minutes. This versatile method works for many types of thin metal and polymeric sheets and is compatible with many tattoo adhesives or medical tapes. The resultant ESS is highly multimaterial and multifunctional and may measure ECG, EMG, skin temperature, skin hydration, as well as respiratory rate. Also, a stretchable planar coil made of serpentine ribbons can be used as a wireless strain gauge and/or a near field communication (NFC) antenna. Other embodiments are described herein.Type: GrantFiled: March 27, 2015Date of Patent: December 3, 2019Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEMInventors: Nanshu Lu, Shixuan Yang, Pulin Wang
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Publication number: 20190345187Abstract: Provided are certain derivatives of amphotericin B (AmB) characterized by reduced toxicity and retained anti-fungal activity. Certain of the derivatives are C16 urea derivatives of AmB. Certain of the derivatives are C3, C5, C8, C9, C11, C13, or C15 deoxy derivatives of AmB. Certain of the derivatives include C3? or C4? modifications of the mycosamine appendage of AmB. Also provided are methods of making AmB derivatives of the invention, pharmaceutical compositions comprising AmB derivatives of the invention, and methods of use of AmB derivatives of the invention.Type: ApplicationFiled: June 17, 2019Publication date: November 14, 2019Inventors: Martin D. Burke, Stephen Davis, Brice E. Uno, Justin Struble, Ian Dailey, Kaitlyn C. Gray, David M. Knapp, Pulin Wang, Nagarjuna Palyam