Abstract: The present invention discloses a light-emitting diode lamp for connecting to an external current source. The LED lamp comprises: a lighting source comprising a plurality of LEDs; a power control module for connecting in parallel to the external current source; and a driver unit connected between the power control module and the lighting source, wherein the power control module is configured to transform a source voltage of the external current source to a desired load voltage based on output power requirement of the plurality of LEDs; and the driver unit is configured to rectify the desired load voltage and output a driving voltage to drive the plurality of LEDs. Without the need to modify a lamp base of a conventional High Intensity Discharge lamp, the LED lamp of the present invention can be directly used to replace the HID lamp.

Abstract: The present invention provides compositions and methods of their use in treating muscular dystrophy and other disorders.

Abstract: The present invention provides compositions and methods of their use in treating dystroglycanopathy, muscular dystrophy and other disorders.

Abstract: The present invention relates to an illumination device, including: a support member; and at least one first light source on the support member and at least one second light source on the support member, where the first light source has a first light distribution, the second light source has a second light distribution, and the first light distribution is different from the second light distribution.

Abstract: This invention provides a ventilation kit adapted to be coupled to a recessed light fixture, and comprises two supporting members. The first is adapted to be coupled with at least one edge of the recessed light fixture, while the second is adapted to be coupled with the gridsystem of the ceiling. There is also through-hole for air circulation. Mounting the ventilation kit onto an existing recessed light fixture enables the existing recessed light fixtures to have either an air supply or air return ventilation feature. This invention also discloses a recessed light fixture assembly with either an air supply or air return ventilation feature.

Abstract: The present invention provides compositions and methods of their use in treating dystroglycanopathy, muscular dystrophy and other disorders.

Abstract: The present invention provides compositions and methods of their use in treating muscular dystrophy and other disorders.

Abstract: A method for controlling the rotational speed of a fan of an LED lamp, comprising: presetting a corresponding relationship between a voltage, a current and a temperature for an LED chip in the LED lamp in the controller, as well as presetting a corresponding relationship between the temperature of LED chip and the speed of the fan in the controller, measuring the voltage and current of the LED chip, obtaining the current calculated temperature of the LED chip through the measured voltage and current, and further determining the current desired fan speed through the obtained current calculated temperature, using the controller to control the fan to rotate at the current desired speed, thereby cooling the LED chip. Additionally a corresponding system for controlling the rotational speed of the fan of an LED lamp and an LED lamp including the system.

Abstract: This disclosure relates biomarkers of cancer, e.g. prostate cancer. The biomarkers may be altered expression of nucleic acids, mutations, or proteins encoded therefrom. In certain embodiments, the disclosure relates to methods for diagnosing prostate cancer, methods of distinguishing between less aggressive and high aggressive prostate cancer, methods of determining predisposition to recurrence of prostate cancer, methods of monitoring progression/regression of prostate cancer, methods of assessing efficacy of compositions for treating prostate cancer, and methods of screening compositions for activity in modulating biomarkers of prostate cancer.

Abstract: The invention relates to synthetic polynucleotides encoding fukutin related protein (FKRP). The invention further relates to nucleic acid constructs comprising the synthetic polynucleotides and methods of using these synthetic polynucleotides to treat dystroglycanopathy disorders.

Abstract: A bipartite capper component for an illuminating lamp includes a first portion formed of a first material and a second portion formed of a second material different from the first material. The second portion of the capper component is in contact with the first portion of the capper component. The first portion of the capper component is configured to threadedly engage within a standard threaded metal base component of the illuminating lamp.

Abstract: The present invention provides methods of delivering a nucleic acid to a cell or tissue, the method including administering the nucleic acid in combination with at least one drug that modulates a membrane transport mechanism. Methods of treating various diseases are also provided.

Abstract: The present invention discloses a lamp, mounted on a socket when in use, comprising a cap, a housing, and a light source, wherein the cap is adapted to connect to the socket, one of the cap and the housing comprises a tubular body, and the other comprises a cylindrical cavity for accommodating the tubular body, and the tubular body rotates in the cylindrical cavity around an axis of the cap and moves along the axial direction of the cap to effect relative rotation and relative telescopic motion between the cap and the housing. The lamp of the present invention allows both relative rotation and relative telescopic motion between the cap and the housing, therefore facilitating adjustment of the illumination direction, and is adaptable to different types of fittings.

Abstract: A solar cell includes a semiconductor wafer, plural finger electrodes, at least one bus electrode, and at least one finger loop electrode. The semiconductor wafer has a light-receiving surface. The finger electrodes are arranged along a first direction and disposed on the light-receiving surface. The bus electrode is arranged along a second direction and disposed on the light-receiving surface, and the bus electrode is connected with the finger electrodes, in which the second direction is perpendicular to the first direction. The finger loop electrode is substantially arranged along the second direction and disposed on the light-receiving surface, and the finger loop electrode is connected to at least two of the finger electrodes, in which the finger loop electrode has a shape of non-square periodic wave.

Abstract: Alkyl nitrate ester compounds are provided for the delivery of nitric oxide to targeted muscle tissues, and in particular, to normal and dystrophic muscles. In one aspect, nitrate ester compounds are provided having the following formula: wherein, R1 is ONO2, CH2ONO2, CnH2n+1OH, CnH2n+1OH, CH3, CH2CH3, CH2CH2CH3, or H; R2 is ONO2, CH2ONO2, Cn?H2n?+1OH, Cn?H2n?+1OH, CH3, CH2CH3, CH2CH2CH3, or H; R3 is ONO2, CH2ONO2, Cn??H2n?+1OH, Cn?H2n?+1OH, CH3, CH2CH3, CH2CH2CH3, or H; and R4 is ONO2, CH2ONO2, Cn??H2n?+1OH, Cn?H2n?+1OH, CH3, CH2CH3, CH2CH2CH3, or H; wherein n is an integer from 0 to 9, n? is an integer from 0 to 9, and n? is an integer from 0 to 9, and n+n?+n??9, and wherein at least one of R1, R2, and R3 is an ester nitrate selected from the group consisting of ONO2, CH2ONO2, and combinations thereof.

Abstract: A testing apparatus for testing a number of different characteristics of a circuit board includes at least two probes, at least one measuring meter, and a storage device. After a circuit schematic diagram of the circuit board and a circuit wiring diagram of the circuit board have been compared, the location of each electric contact is determined. The probes necessary for testing particular characteristics are connected in turn to the measuring meter. The circuit board is moved to align the electric contacts with the probes, and bring the probes into electrical contact with the electric contacts for testing.

Abstract: This disclosure relates biomarkers of cancer, e.g. prostate cancer. The biomarkers may be altered expression of nucleic acids, mutations, or proteins encoded therefrom. In certain embodiments, the disclosure relates to methods for diagnosing pro-state cancer, methods of distinguishing between less aggressive and high aggressive prostate cancer, methods of determining predisposition to recurrence of prostate cancer, methods of monitoring progression/regression of prostate cancer, methods of assessing efficacy of compositions for treating prostate cancer, and methods of screening compositions for activity in modulating biomarkers of prostate cancer.

Abstract: A battery simulation circuit simulates a rechargeable battery. The battery simulation circuit includes an integrated amplifier, a voltage adjustment unit, a current limitation unit, and a feedback unit. The voltage adjustment unit provides a reference voltage for the integrated amplifier; the current limitation unit provides a reference current for the integrated amplifier and the feedback unit provides a negative feedback signal for the integrated amplifier to control the integrated amplifier working in a linear state. The integrated amplifier outputs an output signal according to the reference voltage and the reference current; the battery simulation circuit supplies power for an electronic device. When the output terminal is connected to a DC power source and a voltage of the DC power source is greater than the output voltage of the output terminal, the battery simulation circuit simulates a battery being recharged by the DC power source via the output terminal.

Abstract: A sensing circuit includes a plurality of sensors, a controller, a multiway switch, a linear optocoupler, and a logical control unit. The plurality of sensors are capable of measuring physical quantity, and each of the plurality of sensors is capable of generating a sensing signal in accordance with the physical quantity. The controller is capable of receiving and analyzing the sensing signals, and transforming the sensing signals into sensing events. The multiway switch is capable of selectively connecting one of the plurality of sensors to the controller. The linear optocoupler is connected between the plurality of sensors and the controller. The logical control unit is capable of controlling the multiway switch to selectively connect one of the plurality of sensors to the optocoupler, and generating a control signal to the controller, wherein the control signal indicating the one of the plurality of sensors connected to the controller.