Abstract: The present invention belongs to the field of medicine and relates to a pharmaceutical composition for preventing and treating NITM and a medical use thereof. Specifically, the pharmaceutical composition is an ophthalmic pharmaceutical composition such as an ophthalmic preparation. Specifically, the present invention relates to a pharmaceutical composition comprising 0.001% to 0.2% of atropine or a pharmaceutically acceptable salt thereof, and one or more pharmaceutically acceptable excipients; wherein the pH value of the pharmaceutical composition is of 4.0 to 6.5; the pharmaceutical composition comprises 0.5% to 5% of a pH adjusting agent, and the pH adjusting agent is any one or more selected from sodium dihydrogen phosphate, disodium hydrogen phosphate, citric acid, citrate, boric acid and borates. The pharmaceutical composition of the present invention can effectively treat and/or prevent NITM, and thus has a good application prospect.

Abstract: Disclosed are a model parameter training method and a terminal based on federation learning, and a medium. The method includes: determining a feature intersection of a first sample of the first terminal and a second sample of a second terminal, training the first sample based on the feature intersection to obtain a first mapping model, sending the first mapping model to the second terminal; receiving a second encryption mapping model sent by the second terminal, predicting a missing feature of the first sample of the first terminal according to the second encryption mapping model to obtain a first encryption supplementary sample; receiving a first encryption federation learning model parameter sent by a third terminal, training a federation learning model to be trained according to the first encryption federation learning model parameter, and calculating a first encryption loss value; and sending the first encryption loss value to the third terminal.

Abstract: Disclosed are a federated-learning based method of acquiring model parameters, a system, and a readable storage medium. The method includes: calculating first data of a first terminal and second data of a second terminal to obtain a loss value; and encrypting, by the second terminal, the loss value, and sending, the encrypted loss value to a third terminal; receiving the encrypted loss value sent by the second terminal, by the third terminal, and decrypting the encrypted loss value to obtain the loss value; detecting whether the model to be trained is at convergence according to the loss value after decrypting; in response that the model to be trained is at convergence, acquiring a gradient corresponding to the loss value; and determining a sample parameter corresponding to the gradient, and determining the sample parameter as a model parameter of the model to be trained.

Abstract: Various embodiments include an interlock arrangement that may be used to attach a lens barrel to a lens carrier of a camera. In some embodiments, the interlock arrangement may restrict movement of the lens barrel relative to the lens carrier along at least an optical axis. In various examples, the interlock arrangement may include one or more grooves and one or more protrusions. For instance, a groove may be defined by the lens barrel or the lens carrier, and a protrusion may extend from the lens barrel or the lens carrier to at least partially into the groove. In some cases, the interlock arrangement may include an adhesive that at least partially fills gaps within the interlock arrangement between the lens barrel and the lens carrier. According to some embodiments, the interlock arrangement may include one or more recesses that provide inlets for the adhesive to be introduced to the gaps within the interlock arrangement.

Abstract: In some embodiments, a camera actuator includes an actuator base, an autofocus voice coil motor, and an optical image stabilization voice coil motor. In some embodiments, the autofocus voice coil motor includes a lens carrier mounting attachment moveably mounted to the actuator base, a plurality of shared magnets mounted to the base, and an autofocus coil fixedly mounted to the lens carrier mounting attachment for producing forces for moving a lens carrier in a direction of an optical axis of one or more lenses of the lens carrier. In some embodiments, the optical image stabilization voice coil motor includes an image sensor carrier moveably mounted to the actuator base, and optical image stabilization coils moveably mounted to the image sensor carrier within the magnetic fields of the shared magnets, for producing forces for moving the image sensor carrier in a plurality of directions orthogonal to the optical axis.

Abstract: The present invention provides for recombinant Endo-S2 mutants (named Endo-S2 glycosynthases) that exhibit reduced hydrolysis activity and increased transglycosylation activity for the synthesis of glycoproteins wherein a desired sugar chain is added to a fucosylated or nonfucosylated GlcNAc-IgG acceptor. As such, the present invention allows for the synthesis and remodeling of therapeutic antibodies thereby providing for certain biological activities, such as, prolonged half-life time in vivo, less immunogenicity, enhanced in vivo activity, increased targeting ability, and/or ability to deliver a therapeutic agent.

Abstract: Various embodiments include an interlock arrangement that may be used to attach a lens barrel to a lens carrier of a camera. In some embodiments, the interlock arrangement may restrict movement of the lens barrel relative to the lens carrier along at least an optical axis. In various examples, the interlock arrangement may include one or more grooves and one or more protrusions. For instance, a groove may be defined by the lens barrel or the lens carrier, and a protrusion may extend from the lens barrel or the lens carrier to at least partially into the groove. In some cases, the interlock arrangement may include an adhesive that at least partially fills gaps within the interlock arrangement between the lens barrel and the lens carrier. According to some embodiments, the interlock arrangement may include one or more recesses that provide inlets for the adhesive to be introduced to the gaps within the interlock arrangement.

Abstract: A visual interpretation method and a device for a logistic regression model, relating to the computer technology field. The method includes: receiving an interpretation request for a logistic regression model (S11); obtaining, according to the interpretation request, model parameters of the logistic regression model, the model parameters comprising each feature in the logistic regression model and a weight value of each feature (S12); aggregating each feature in the obtained model parameters according to a feature name (S13); obtaining feature statistics for each feature name to obtain feature statistics information for each feature name, wherein the feature statistics information indicates distribution information of weight values of each feature under the same feature name and/or dimension information of each feature under the same feature name (S14); and displaying the feature name and the corresponding feature statistics information using a graphical interface (S15).

Abstract: In some embodiments, a camera actuator includes an actuator base, an autofocus voice coil motor, and an optical image stabilization voice coil motor. In some embodiments, the autofocus voice coil motor includes a lens carrier mounting attachment moveably mounted to the actuator base, a plurality of shared magnets mounted to the base, and an autofocus coil fixedly mounted to the lens carrier mounting attachment for producing forces for moving a lens carrier in a direction of an optical axis of one or more lenses of the lens carrier. In some embodiments, the optical image stabilization voice coil motor includes an image sensor carrier moveably mounted to the actuator base, and optical image stabilization coils moveably mounted to the image sensor carrier within the magnetic fields of the shared magnets, for producing forces for moving the image sensor carrier in a plurality of directions orthogonal to the optical axis.

Abstract: A hybrid sensor shift platform for an optical image stabilization (OIS) actuator mechanism in compact camera modules includes two or more substrates. A top substrate is composed of an organic material (e.g., a resin) to reduce mass, reduce magnetic interaction with permanent magnets, and improve reliability. One or more lower substrates of the hybrid sensor shift platform are ceramic substrates that provide the benefits of ceramics for connection to the image sensor. The organic substrate is connected via a solder bond process to the lower ceramic substrate(s). The connection between the substrates is reinforced with an under-fill of epoxy that surrounds the solder bonds, thus creating a full interface between the substrates within the overlap.

Abstract: In some embodiments, a camera includes an optical package, a camera actuator for moving the optical package, a camera cover, and an impact absorption member to prevent contact between the camera cover and the lens carrier. In some embodiments, the camera actuator includes a lens carrier moveably mounted to a camera cover.

Abstract: Provided are method, apparatus and system for performing machine learning by using data to be exchanged. The apparatus includes: at least one computing device and at least one storage device storing instructions.

Abstract: Various embodiments include a damper arrangement that may be used to dampen motions of a dynamic component. In some embodiments, the damper arrangement may be used in a camera module that includes a stationary component and a dynamic component. For instance, the dynamic component may hold a lens such that the lens moves together with the dynamic component. In various examples, the damper arrangement may include an interface member that extends from the stationary component or the dynamic component to at least partially into a viscoelastic material within a pocket configured in the stationary component, the dynamic component, or both. The interface member may be configured to traverse within the viscoelastic material to dampen motion of the dynamic component, for example, during operation of a lens actuator to move the dynamic component along an optical axis of the lens.

Abstract: A platform for constraining a workpiece includes x-y stage connected to a base, wherein the x-y stage includes a floor and a y-axis datum and a x-axis datum aligned along a first axis and a second axis perpendicular to the first axis, respectively, and a primary constraint mechanism on the x-y stage. The primary constraint mechanism includes an x-axis wedge, a primary y-axis wedge and a primary z-axis clamp, and a primary linear actuator with a rod extendable and retractable parallel to the second axis. A primary linear actuator slides the x-axis wedge away from the x-axis datum, slides the primary y-axis wedge away from the y-axis datum, and rotates the primary z-axis clamp away from the workpiece. The primary z-axis clamp is attached to a cam with a pinion gear that engages a rack gear connected to the rod of the primary linear actuator.

Abstract: Provided herein is a process for the preparation of 4-((6-(2-(2,4-difluorophenyl)-1,1-difluoro-2-hydroxy-3-(5-mercapto-1H-1,2,4-triazol-1-yl)propyl)pyridin-3-yl)oxy)benzonitrile.

Abstract: In some embodiments, a camera includes an optical package, a camera actuator for moving the optical package, a camera cover, and an impact absorption member to prevent contact between the camera cover and the lens carrier. In some embodiments, the camera actuator includes a lens carrier moveably mounted to a camera cover.

Abstract: An automated pin anvil press for connecting a workpiece pair at a plurality of pin locations with a plurality of pins includes a platform, an anvil paired with a puncher, and a position control camera capable of taking position alignment images. The platform includes a base, an x-y stage including a floor with a central opening and a y-axis datum and a x-axis datum aligned along a first axis and a second axis perpendicular to the first axis, respectively, and a primary constraint mechanism on the x-y stage wherein activation of the primary constraint mechanism constrains at least one of the workpiece pair on the x-y stage. The platform also includes x-axis and y-axis carriages connecting the x-y stage to the base, wherein activation of an x-axis actuator connected to the x-axis carriage moves the x-y stage parallel to the first axis.

Abstract: A picture ranking method and a terminal comprises acquiring pictures stored in a terminal, detecting whether the pictures are first-type pictures, where a first-type picture refers to a picture including a human face, and when the pictures are first-type pictures, ranking the pictures according to a social relation model, or when the pictures are not first-type pictures, ranking the pictures according to a preset rule.

Abstract: A two degree-of-freedom actuator includes a first linkage, a second linkage, a third linkage, a magnet, a winding panel, and a plurality of windings. The second linkage is rotationally coupled to the first linkage, whereby the first linkage is rotatable, relative to the second linkage, about a first rotational axis. The third linkage is rotationally coupled to the second linkage, whereby the first and second linkages are rotatable, relative to the third linkage, about a second rotational axis that is perpendicular to the first rotational axis. The magnet is fixedly mounted on the first linkage. The winding panel is fixedly mounted to the third linkage and has an inner surface and an opposing outer surface. The inner surface faces the magnet and is spaced apart therefrom. The windings are wound around the winding panel.

Abstract: Various embodiments include a damper arrangement that may be used to dampen motions of a dynamic component. In some embodiments, the damper arrangement may be used in a camera module that includes a stationary component and a dynamic component. For instance, the dynamic component may hold a lens such that the lens moves together with the dynamic component. In various examples, the damper arrangement may include an interface member that extends from the stationary component or the dynamic component to at least partially into a viscoelastic material within a pocket configured in the stationary component, the dynamic component, or both. The interface member may be configured to traverse within the viscoelastic material to dampen motion of the dynamic component, for example, during operation of a lens actuator to move the dynamic component along an optical axis of the lens.