Patents by Inventor Qing Xia

Qing Xia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210024935
    Abstract: Provided is a method for high-efficiently reading through a nonsense mutation site in a pathogenic gene in a monogenic hereditary disease and restoring the normal structure and function of a mutant protein, by using a genetic code expanded non-natural amino acid system. By modifying a tRNA of Methanosarcina barkeri (tRNAPyl), an all-new UAA and UGA encoded non-natural amino acid system that has high read-through efficiency is obtained, and the range of using the orthogonal pair of tRNAPyl and pyrrolysyl-tRNA synthetase (PylRS) is expanded. A plasmid mimicking the endogenous premature termination codon is constructed, so as to evaluate the efficiency of reading through the endogenous premature termination codon. Also provided is a system mainly comprising pathogenic genes of monogenic hereditary diseases and tumor inhibitory genes in tumor cells.
    Type: Application
    Filed: August 6, 2020
    Publication date: January 28, 2021
    Inventors: Qing Xia, Qi Yang
  • Patent number: 10890432
    Abstract: A digital displacement sensor and a displacement measuring method thereof, pertaining to the technical field of displacement sensors. The digital displacement sensor includes a housing and a circuit board, and the circuit board is arranged inside the housing. The housing is provided with a window and an opening. The circuit board is provided with a signal acquisition module, an analog front end circuit, a digital compensation circuit, and a signal output interface. The digital displacement sensor allows to alternatively fix the sensor or measured object according to the structure. The measurement can be performed as long as a relative movement between the sensor and the measured object occurs. Factors such as material of the measured object etc. are not limited, so materials such as steel belts, aluminum plates, plastics etc. can be flexibly used. Merely surfaces of the measured object need to be coated with corresponding stripes.
    Type: Grant
    Filed: July 9, 2018
    Date of Patent: January 12, 2021
    Assignee: MONOLITH ELECTRIC (CHANGZHOU) CO., LTD.
    Inventors: Lei Liang, Qing Xia, Weijie Wu, Chunlei Yu
  • Patent number: 10852345
    Abstract: A circuit board testing device electrically coupled to a measurement gauge tests a circuit board. The circuit board testing device includes a processor configured to configure measurement parameters of the measurement gauge, configure measurement rules for testing the circuit board, confirm a circuit of the circuit board to be tested according to the record of test data, control the measurement gauge to test the circuit of the circuit board to be tested when the measurement gauge is electrically coupled to the circuit of the circuit board to be tested, receive measurement data returned by the measurement gauge, and analyze a faulty region of the circuit board according to the record of test data and the measurement data.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: December 1, 2020
    Assignees: HONGFUJIN PRECISION ELECTRONICS (CHENGDU) Co., Ltd., HON HAI PRECISION INDUSTRY CO., LTD.
    Inventors: Qiang Liu, Wen-Wen Zhou, Meng Wang, Zi-Qing Xia, Zhi-Gao Wu
  • Publication number: 20200333337
    Abstract: The present invention is directed an immunoassay method, which re-uses an antibody-immobilized test probe and reagents for quantitating an analyte in different samples, anywhere from about 3 to 20 times, while maintaining acceptable clinical assay performance. The method regenerates the test probe by dipping the test probe in an acidic solution having pH about 1-4, after the completion of each cycle of reaction. The present invention is also directed to a unitized cartridge (a strip) for an immunoassay test. Each unitized cartridge contains all necessary reagents can be used for 3-20 cycles to measure 3-20 different samples.
    Type: Application
    Filed: July 1, 2020
    Publication date: October 22, 2020
    Inventors: Robert F. Zuk, Qing Xia
  • Patent number: 10809251
    Abstract: The present invention is directed to methods for increasing sensitivities of immunoassays. The invention utilizes an acid elution condition that preferentially elute specifically bound immune complexes over non-specifically bound complexes from a solid phase, and designs immunoassay protocols that improve the ratio of specific binding to non-specific binding and thereby improving assay sensitivity. The protocol determines the signal of the labeled immunocomplexes eluted from a solid phase.
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: October 20, 2020
    Assignee: ACCESS MEDICAL SYSTEMS, LTD.
    Inventors: Robert F. Zuk, Hong Tan, Qing Xia, Pu Li, Haode Chen, Heng Wu
  • Publication number: 20200292471
    Abstract: A solder paste printing quality inspection (SPI) method includes establishing at least one data inspection model, acquiring real-time test data, preprocessing the real-time test data, and determining a type of the real-time test data and inputting the real-time test data into the data inspection model corresponding to the type of the real-time test data to obtain a judgment result of the solder paste printing quality inspection. The real-time test data includes one or both of a test image and a test value of solder paste printing quality inspection. The preprocessing includes obtaining key parameters of the test value or obtaining image data of the test image and standardizing the real-time test data.
    Type: Application
    Filed: April 30, 2019
    Publication date: September 17, 2020
    Inventors: ZI-QING XIA, XIAO-LEI LIU, MIN CHEN, YI-KUN WANG, FU-JU ZENG
  • Publication number: 20200268870
    Abstract: The present invention relates to a mutated virus. Said virus can be an influenza virus of human or other animal origin. The present invention also relates to a method for preparing the mutated virus, the method comprising introducing UAG codons into positions upstream of the stop codons per se of one or more genes of a viral genome by reverse genetic techniques. The present invention further relates to uses of the mutated virus, for example, as a live attenuated vaccine, or in replication of controllable and safe virus models, and the like.
    Type: Application
    Filed: August 2, 2016
    Publication date: August 27, 2020
    Inventors: Demin Zhou, Longlong Si, Xueying Zhou, Ziwei Zhang, Huan Xu, Zhenyu Tian, Chuanling Zhang, Sulong Xiao, Qing Xia, Lihe Zhang
  • Publication number: 20200233021
    Abstract: The present disclosure provides a method and a device for detecting electricity theft, and a computer readable medium, smart meter data of each user and aggregated electricity consumption data are obtained during the detection period in the target area, a load profile set and non-technical loss data are obtained, and a correlation between each load profile in the load profile set and the non-technical loss data is obtained through a maximum information coefficient method and based on the smart meter data and the aggregated electricity consumption data, so as to obtain a correlation indicator for measuring the correlation.
    Type: Application
    Filed: April 9, 2020
    Publication date: July 23, 2020
    Inventors: Qixin CHEN, Kedi ZHENG, Yi WANG, Chongqing KANG, Qing XIA
  • Publication number: 20200212681
    Abstract: A method, an apparatus and a storage medium for transmission network expansion planning considering extremely large amounts of operation scenarios is provided. The method comprises establishing an optimization model for transmission network expansion planning, the optimization model including an objective function for minimizing the sum of investment costs for the transmission lines and expected values of operation costs in the power transmission network, solving the optimization model to obtain an optimal investment decision variable; and determining the transmission network expansion planning based on the optimal investment decision variable.
    Type: Application
    Filed: January 2, 2020
    Publication date: July 2, 2020
    Inventors: Zhenyu Zhuo, Ning Zhang, Yi Wang, Chongqing Kang, Qing Xia
  • Publication number: 20200208961
    Abstract: A digital displacement sensor and a displacement measuring method thereof, pertaining to the technical field of displacement sensors. The digital displacement sensor includes a housing and a circuit board, and the circuit board is arranged inside the housing. The housing is provided with a window and an opening. The circuit board is provided with a signal acquisition module, an analog front end circuit, a digital compensation circuit, and a signal output interface. The digital displacement sensor allows to alternatively fix the sensor or measured object according to the structure. The measurement can be performed as long as a relative movement between the sensor and the measured object occurs. Factors such as material of the measured object etc. are not limited, so materials such as steel belts, aluminum plates, plastics etc. can be flexibly used. Merely surfaces of the measured object need to be coated with corresponding stripes.
    Type: Application
    Filed: July 9, 2018
    Publication date: July 2, 2020
    Applicant: Monolith Electric (Changzhou) Co.,Ltd.
    Inventors: Lei LIANG, Qing XIA, Weijie WU, Chunlei YU
  • Publication number: 20200161863
    Abstract: A dispatch method and device for a power system are provided. The method includes: establishing an optimal power flow model, the optimal power flow model includes an objective function and constraints, the objective function is configured to indicate a minimum total cost of active power production and reactive power production of generators; solving the optimal power flow model to obtain dispatch parameters for the power system; and dispatching the power system based on the dispatch parameters.
    Type: Application
    Filed: January 24, 2020
    Publication date: May 21, 2020
    Inventors: Zhifang YANG, Haiwang ZHONG, Qing XIA, Chunling LU, Xiaowen LAI, Yang WANG
  • Publication number: 20200103461
    Abstract: A circuit board testing device electrically coupled to a measurement gauge tests a circuit board. The circuit board testing device includes a processor configured to configure measurement parameters of the measurement gauge, configure measurement rules for testing the circuit board, confirm a circuit of the circuit board to be tested according to the record of test data, control the measurement gauge to test the circuit of the circuit board to be tested when the measurement gauge is electrically coupled to the circuit of the circuit board to be tested, receive measurement data returned by the measurement gauge, and analyze a faulty region of the circuit board according to the record of test data and the measurement data.
    Type: Application
    Filed: November 29, 2018
    Publication date: April 2, 2020
    Inventors: QIANG LIU, WEN-WEN ZHOU, MENG WANG, ZI-QING XIA, ZHI-GAO WU
  • Publication number: 20190384130
    Abstract: A display panel includes a pixel electrode, a common electrode line, and a dielectric layer disposed between the pixel electrode and the common electrode line. The common electrode line is made of a transparent conductive material. The common electrode line and the pixel electrode are arranged to overlap each other to form a storage capacitor.
    Type: Application
    Filed: June 29, 2017
    Publication date: December 19, 2019
    Applicant: Shenzhen China Star Optoelectronics Technology Co., Ltd.
    Inventors: Qing XIA, Li CHAI
  • Patent number: 10389706
    Abstract: A method and system for authenticating a user is provided. In some embodiments, a security system determines whether the time since the last authentication was successful is less than a recycle telephone number period (e.g., the minimum time before which a telephone number might be assigned to a new user). If the time is less than the recycle telephone number period, the security system performs a primary authentication of the user based on a telephone number received from the user. When the primary authentication is successful, the security system indicates that the user has been authenticated. When the time is not less than a recycle telephone number period, the security system performs a secondary authentication of the user. When the secondary authentication is successful, the security system indicates that the user has been authenticated.
    Type: Grant
    Filed: August 1, 2016
    Date of Patent: August 20, 2019
    Assignee: MICROSOFT TECHNOLOGY LICENSING, LLC
    Inventors: Benjamin Richard Vincent, Li Qing Xia
  • Publication number: 20190250154
    Abstract: The present invention is directed an immunoassay method using an interference detection system. The assay re-uses an antibody-immobilized test probe and reagents for quantitating an analyte in different samples, from about 3 to 20 times, while maintaining acceptable clinical assay performance. The method regenerates the test probe with an acidic solution after completion of each cycle of reactions. The present invention is also directed to a unitized cartridge (a strip) for an immunoassay test. Each unitized cartridge contains all necessary reagents and can be used for 3-20 cycles to measure 3-20 different samples.
    Type: Application
    Filed: April 25, 2019
    Publication date: August 15, 2019
    Inventors: Robert F. Zuk, Qing Xia
  • Publication number: 20190147464
    Abstract: Disclosed is a method for clearing electric quantity market, including: acquiring a RSI of each of a plurality of market entities; judging whether a market power exceeds a threshold according to the RSI of the market entity; adjusting an electric quantity declared by a power generation entity and a market demand electric quantity; evaluating the market power under a new environment and judging whether the market power meets a preset condition; adjusting a quoting function of each of the plurality of market entities in a CTCP and acquiring an adjustment situation; clearing transactions of each of the plurality of market entities in the CTCP according to the adjustment situation and acquiring a market clearing situation of the CTCP; distributing a CPSP in the preset electric quantity market according to the market clearing situation of the CTCP; and settling and clearing transactions according to a clearing amount and a clearing price.
    Type: Application
    Filed: July 6, 2018
    Publication date: May 16, 2019
    Inventors: Qixin CHEN, Hongye GUO, Qing XIA, Chongqing KANG
  • Patent number: 10289765
    Abstract: The present disclosure provides a fast model generating and solving method for security-constrained power system operation simulation, which includes: obtaining information of all branches and nodes which are involved during operation simulation time period, calculating original-node impedance matrix, load shifting distribution factor original matrix and generator shifting distribution factor original matrix of all involved branches; correcting the load shifting distribution factor original matrix and the generator shifting distribution factor original matrix according to the on-off state of branches; obtaining output of each generator unit at each time period according to no-security-constraint unit commitment model, and determining overload of each branch again; solving iteratively until no branch is overloaded, and obtaining output of each generator unit at each time period under security constraint of operation simulation for the current simulation day, performing operating simulation for the rest simulat
    Type: Grant
    Filed: August 26, 2016
    Date of Patent: May 14, 2019
    Assignee: TSINGHUA UNIVERSITY
    Inventors: Ning Zhang, Chongqing Kang, Qing Xia, Ershun Du
  • Publication number: 20190119675
    Abstract: Provided are a method for constructing a suppressor tRNA, and 19 suppressor tRNAs corresponding to three termination codons, a plasmid, a vector or a kit comprising the above-mentioned tRNA. Also provided are use of the above-mentioned tRNA, plasmid, vector or kit in the manufacture of a medicament for treating a hereditary disease or a cancer caused by a nonsense mutation of a gene. Also provided are a method for evaluating the efficiency of a suppressor tRNA for reading through a nonsense mutation, and a method for restoring the expression of a truncated protein of a nonsense mutant of a pathogenic gene in a monogenic hereditary disease and a tumor suppressor gene in a tumor cell.
    Type: Application
    Filed: March 3, 2017
    Publication date: April 25, 2019
    Inventors: Qing Xia, Tianchang Wang, Qi Yang
  • Publication number: 20190062753
    Abstract: Provided is a method for high-efficiently reading through a nonsense mutation site in a pathogenic gene in a monogenic hereditary disease and restoring the normal structure and function of a mutant protein, by using a genetic code expanded non-natural amino acid system. By modifying a tRNA of Methanosarcina barkeri (tRNAPyl), an all-new UAA and UGA encoded non-natural amino acid system that has high read-through efficiency is obtained, and the range of using the orthogonal pair of tRNAPyl and pyrrolysyl-tRNA synthetase (PylRS) is expanded. A plasmid mimicking the endogenous premature termination codon is constructed, so as to evaluate the efficiency of reading through the endogenous premature termination codon. Also provided is a system mainly comprising pathogenic genes of monogenic hereditary diseases and tumor inhibitory genes in tumor cells.
    Type: Application
    Filed: March 3, 2017
    Publication date: February 28, 2019
    Inventors: Qing Xia, Qi Yang
  • Patent number: 10203312
    Abstract: The present disclosure provides a system for measuring carbon emissions in a power system. The system includes: generation carbon meters, distributed respectively in generators in the power system; network carbon meters, distributed respectively in nodes in the power system; consumption carbon meters, distributed respectively in consumers in the power system; and a center server, in which each carbon meter is configured to collect data for measuring the carbon emissions. The center server is configured to acquire the collected data and to measure the carbon emissions according to the acquired data, and to send measuring results to the corresponding carbon meter. Then each carbon meter is further configured to display according to the measuring results. The carbon emission may be measured in real time.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: February 12, 2019
    Assignee: TSINGHUA UNIVERSITY
    Inventors: Chongqing Kang, Yaohua Cheng, Ning Zhang, Qixin Chen, Qing Xia