Patents by Inventor Qingguo Lu
Qingguo Lu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230219872Abstract: Disclosed is an industrial extraction method of cannabidiol, pertaining to the field of medicine and chemical industry. The present invention aims to resolve the problems of difficulty in wax removal, low extraction rate of cannabidiol, and excessively high content of tetrahydrocannabinol during extraction using conventional solvents in the prior art. The extraction method employs raw material pretreatment, granulation, extraction, liquid-liquid extraction, decolorization, concentration, and other processes, such that wax removal from an extracted liquid is improved, the purity of a crude cannabidiol oil can be increased to 60%, and 40% of tetrahydrocannabinol can be removed. The method has high extraction yields and low costs, and can be implemented in large-scale industrial production.Type: ApplicationFiled: May 27, 2021Publication date: July 13, 2023Applicant: CHENGUANG BIOTECH GROUP CO., LTD.Inventors: Qingguo LU, Yunhe LIAN, Wei Gao, Yang LI, Hong TIAN
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Publication number: 20230122252Abstract: A composition contains quercetagetin and 6-hydroxykaempferol, and, optionally further includes patuletin. The composition has an excellent antioxidant effect, and can be used as an active additive in food, drugs, health care products, cosmetics, and feed. In addition, the composition can prompt animal growth, reduce ratio of feed to gain, and improve meat quality in the feed.Type: ApplicationFiled: March 10, 2021Publication date: April 20, 2023Inventors: Qingguo LU, Di WU, Yunhe LIAN, Xiuzhai QIN, Shaodong JI, Xinying CHENG
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Patent number: 11549128Abstract: A pretreatment method for producing a raw material of lycopene, comprising: uniformly mixing tomato peel residue with a fermenting agent, an antioxidant and an enzyme preparation, and subjecting the resultant to light-proof anaerobic fermentation. The present invention employs bacteria-enzyme-combined fermentation technology, which prolongs the storage period of wet tomato peel residue, and also destroys the cell wall of tomato peels, thus facilitating exaction of lycopene and improving the purity of lycopene extracted in the later stage.Type: GrantFiled: October 25, 2017Date of Patent: January 10, 2023Assignee: CHENGUANG BIOTECH GROUP CO., LTD.Inventors: Qingguo Lu, Wenjie Han, Zhiming Zhang, Xiaodong An, Wei Gao, Qianli Li
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Patent number: 11499052Abstract: The present invention relates to a method for preparing lycopene crystals with high purity and low harm. The method comprises the following steps: (1) mixing lycopene oleoresin with a mixed solvent consisting of an alkane and a lower alcohol, and heating and stirring the resultant for dissolution to form a homogenous solution; (2) cooling the homogenous solution for crystallization, filtering the resultant to obtain a filter cake; and (3) washing the filter cake successively using a lower alcohol and an alkane, and drying the resultant to obtain lycopene crystals. According to the method provided by the present invention, lycopene crystals can be obtained using a mixed solvent by means of one step crystallization, and the crystal content is further improved and harmful substances in the crystals are reduced by means of a two-step crystal washing process to obtain lycopene crystals with high purity and low harm.Type: GrantFiled: October 25, 2017Date of Patent: November 15, 2022Assignee: CHENGUANG BIOTECH GROUP CO., LTD.Inventors: Qingguo Lu, Yunhe Lian, Zhiming Zhang, Xiaodong An, Qianli Li, Wei Gao
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Patent number: 11278856Abstract: A lutein microcapsule formulation and preparation method thereof, the formulation comprising the following ingredients: lutein crystals, a water-soluble emulsifier, an oil-soluble antioxidant, a wall material, a filler, a water-soluble antioxidant, and purified water. The preparation method comprises: dissolving the lutein crystals and the oil-soluble antioxidant in the water-soluble emulsifier to obtain an oil phase; adding the wall material, the water-soluble antioxidant, and the filler to the purified water to obtain a water phase; adding the oil phase to the water phase, grinding to obtain a particle size of the liquid emulsion of less than 100 nm, and granulating.Type: GrantFiled: January 28, 2015Date of Patent: March 22, 2022Assignee: CHENGUANG BIOTECH GROUP CO., LTDInventors: Qingguo Lu, Jianzhong Xu, Yunhe Lian
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Publication number: 20200347234Abstract: The present invention relates to a method for preparing lycopene crystals with high purity and low harm. The method comprises the following steps: (1) mixing lycopene oleoresin with a mixed solvent consisting of an alkane and a lower alcohol, and heating and stirring same for dissolution to form a homogenous solution; (2) cooling and crystallizing the homogenous solution, filtering same to obtain a filter cake; (3) washing the filter cake successively using a lower alcohol and an alkane, and drying same to obtain lycopene crystals. According to the method provided by the present invention, lycopene crystals can be obtained using a mixed solvent by means of one step crystallization, and the crystal content is further improved and harmful substances in the crystals are reduced by means of a two-step crystal washing process to obtain lycopene crystals with high purity and low harm.Type: ApplicationFiled: October 25, 2017Publication date: November 5, 2020Inventors: Qingguo Lu, Yunhe Lian, Zhiming Zhang, Xiaodong An, Qianli Li, Wei Gao
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Publication number: 20200318143Abstract: A pretreatment method for producing a raw material of lycopene, comprising: uniformly mixing tomato peel residue with a fermenting agent, an antioxidant and an enzyme preparation, and subjecting the resultant to light-proof anaerobic fermentation. The present invention employs bacteria-enzyme combined fermentation technology, which prolongs the storage period of wet tomato peel residue, and also destroys the cell wall of tomato peels, thus facilitating exaction of lycopene and improving the purity of lycopene extracted in the later stage.Type: ApplicationFiled: October 25, 2017Publication date: October 8, 2020Inventors: Qingguo Lu, Wenjie Han, Zhiming Zhang, Xiaodong An, Wei Gao, Qianli Li
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Publication number: 20180021749Abstract: A lutein microcapsule formulation and preparation method thereof, the formulation comprising the following ingredients: lutein crystals, a water-soluble emulsifier, an oil-soluble antioxidant, a wall material, a filler, a water-soluble antioxidant, and purified water. The preparation method comprises: dissolving the lutein crystals and the oil-soluble antioxidant in the water-soluble emulsifier to obtain an oil phase; adding the wall material, the water-soluble antioxidant, and the filler to the purified water to obtain a water phase; adding the oil phase to the water phase, grinding to obtain a particle size of the liquid emulsion of less than 100 nm, and granulating.Type: ApplicationFiled: January 28, 2015Publication date: January 25, 2018Inventors: Qingguo LU, Jianzhong XU, Yunhe LIAN
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Patent number: 9765062Abstract: The present invention relates to a method for producing silymarin. The method comprises: pressing silybum marianum seeds to obtain silymarin powder, and soaking the silymarin powder by using alkaline water; extracting, by using acetone, the silymarin powder soaked by using alkaline water, and performing filtering and concentration on the extracted liquid to obtain a concentrated solution; and performing extraction on the concentrated solution by using a non-polar solvent, performing separation to obtain a non-polar solvent layer and an acetone layer, and concentrating and drying the acetone layer to obtain silymarin. The method can greatly improve the extraction efficiency and the yield, shorten the extraction time, needs simple processes and low cost and thoroughly remove residual oil, so that the product has a low impurity, high product quality and a high purity; and the method is applicable to industrial production and has a great application prospect and economic value.Type: GrantFiled: December 30, 2013Date of Patent: September 19, 2017Assignee: Chenguang Biotech Group Co., Ltd.Inventors: Qingguo Lu, Yunhe Lian, Hong Tian, Xinying Cheng, Zhipeng Duan
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Publication number: 20160326145Abstract: The present invention relates to a method for producing silymarin. The method comprises: pressing silybum marianum seeds to obtain silymarin powder, and soaking the silymarin powder by using alkaline water; extracting, by using acetone, the silymarin powder soaked by using alkaline water, and performing filtering and concentration on the extracted liquid to obtain a concentrated solution; and performing extraction on the concentrated solution by using a non-polar solvent, performing separation to obtain a non-polar solvent layer and an acetone layer, and concentrating and drying the acetone layer to obtain silymarin. The method can greatly improve the extraction efficiency and the yield, shorten the extraction time, needs simple processes and low cost and thoroughly remove residual oil, so that the product has a low impurity, high product quality and a high purity; and the method is applicable to industrial production and has a great application prospect and economic value.Type: ApplicationFiled: December 30, 2013Publication date: November 10, 2016Inventors: Qingguo LU, Yunhe LIAN, Hong TIAN, Xinying CHENG, Zhipeng Duan
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Patent number: 9434886Abstract: A process for extracting lycopene, comprising the following steps: pressing and dehydrating tomato pomace which is the by-products of tomato processing production, then drying it to control the water content in the range from 10% to 20%; crushing the dried tomato pomace, and separating tomato skins and tomato seeds by air blast process, granulating the separated tomato skins and extracting them, then purifying by removing impurity from the extracted lycopene with active carbon.Type: GrantFiled: December 31, 2011Date of Patent: September 6, 2016Assignee: Chenguang Biotech Group Co. Ltd.Inventors: Qingguo Lu, Yunhe Lian, Wenjie Han, Yuhai Tong, Xuehui Su, Xiaodong An, Junqiang Zhang
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Patent number: 8921615Abstract: Disclosed a process for preparing a xanthophyll crystal, comprising: dissolving the plant extract containing a xanthophyll ester in n-hexane, then filtering the mixture; adding acetone to the filtrate, filtering and collecting a filter cake; mixing the filter cake with soybean oil and ethanol uniformly; saponifying the mixed solution with alkaline aqueous solution; then adding an acidic solution thereto until the mixed solution becomes acidic, concentrating under reduced pressure to obtain a pasty substance; adding n-hexane to the pasty saponified product, standing still and then conducting a solid-liquid separation; washing the resulting solid substance with deionized water; adding a mixed solvent to the washed solid substance, dissolving it with stirring; and then adding n-hexane thereto and standing still to recrystallize.Type: GrantFiled: December 31, 2011Date of Patent: December 30, 2014Assignee: Chenguang Biotech Group Co. Ltd.Inventors: Qingguo Lu, Yunhe Lian, Xuehui Su, Xiaodong An, Yuanxin Cheng, Lijun Qi
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Publication number: 20140316175Abstract: A process for extracting lycopene, comprising the following steps: pressing and dehydrating tomato pomace which is the by-products of tomato processing production, then drying it to control the water content in the range from 10% to 20%; crushing the dried tomato pomace, and separating tomato skins and tomato seeds by air blast process, granulating the separated tomato skins and extracting them, then purifying by removing impurity from the extracted lycopene with active carbon.Type: ApplicationFiled: December 31, 2011Publication date: October 23, 2014Applicant: CHENGUANG BIOTECH GROUP CO. LTD.Inventors: Qingguo Lu, Yunhe Lian, Wenjie Han, Yuhai Tong, Xuehui Su, Xiaodong An, Junqiang Zhang
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Publication number: 20140303406Abstract: Disclosed a process for preparing a xanthophyll crystal, comprising: dissolving the plant extract containing a xanthophyll ester in n-hexane, then filtering the mixture; adding acetone to the filtrate, filtering and collecting a filter cake; mixing the filter cake with soybean oil and ethanol uniformly; saponifying the mixed solution with alkaline aqueous solution; then adding an acidic solution thereto until the mixed solution becomes acidic, concentrating under reduced pressure to obtain a pasty substance; adding n-hexane to the pasty saponified product, standing still and then conducting a solid-liquid separation; washing the resulting solid substance with deionized water; adding a mixed solvent to the washed solid substance, dissolving it with stirring; and then adding n-hexane thereto and standing still to recrystallize.Type: ApplicationFiled: December 31, 2011Publication date: October 9, 2014Applicant: CHENGUANG BIOTECH GROUP CO., LTD.Inventors: Qingguo Lu, Yunhe Lian, Xuehui Su, Xiaodong An, Yuanxin Cheng, Lijun Qi