Patents by Inventor Qisheng Xin

Qisheng Xin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Retinoic acid receptor antagonists as chaperone-mediated autophagy modulators and uses thereof
    Patent number: 11591324
    Abstract: Compounds, compositions and methods are provided for selectively activating chaperone-mediated autophagy (CMA), protecting cells from oxidative stress, proteotoxicity and lipotoxicity, and/or antagonizing activity of retinoic acid receptor alpha (RAR?) in subjects in need thereof.
    Type: Grant
    Filed: August 4, 2020
    Date of Patent: February 28, 2023
    Assignee: ALBERT EINSTEIN COLLEGE OF MEDICINE, INC.
    Inventors: Ana Maria Cuervo, Evripidis Gavathiotis, Qisheng Xin, Bhaskar C. Das
  • INJECTABLE POLYMER NANOPARTICLE COMPOSITIONS OF ANTITHROMBOTIC AGENTS AND METHODS THEREOF
    Publication number: 20220218608
    Abstract: Disclosed are injectable nanoparticle compositions comprising a micelle formulation of an antithrombotic agent and a water-soluble, biodegradable, and amphiphilic polymer that improves water solubility of the antithrombotic agent. A method of preparing the injectable nanoparticle compositions and methods for preventing or treating thrombotic diseases such as venous thromboembolisms and/or stroke using the compositions, as well as devices and kits suitable for such treatment, are also disclosed.
    Type: Application
    Filed: May 8, 2020
    Publication date: July 14, 2022
    Applicant: FORDOZ Pharma Corp.
    Inventors: QISHENG XIN, SYDNEY UGWU, JAMES HE
  • RETINOIC ACID RECEPTOR ANTAGONISTS AS CHAPERONE-MEDIATED AUTOPHAGY MODULATORS AND USES THEREOF
    Publication number: 20210053958
    Abstract: Compounds, compositions and methods are provided for selectively activating chaperone-mediated autophagy (CMA), protecting cells from oxidative stress, proteotoxicity and lipotoxicity, and/or antagonizing activity of retinoic acid receptor alpha (RAR?) in subjects in need thereof.
    Type: Application
    Filed: August 4, 2020
    Publication date: February 25, 2021
    Inventors: Ana Maria CUERVO, Evripidis GAVATHIOTIS, Qisheng XIN, Bhaskar C. DAS
  • Retinoic acid receptor antagonists as chaperone-mediated autophagy modulators and uses thereof
    Patent number: 10766886
    Abstract: Compounds, compositions and methods are provided for selectively activating chaperone-mediated autophagy (CMA), protecting cells from oxidative stress, proteotoxicity and lipotoxicity, and/or antagonizing activity of retinoic acid receptor alpha (RAR?) in subjects in need thereof.
    Type: Grant
    Filed: December 5, 2018
    Date of Patent: September 8, 2020
    Assignee: ALBERT EINSTEIN COLLEGE OF MEDICINE
    Inventors: Ana Maria Cuervo, Evripidis Gavathiotis, Qisheng Xin, Bhaskar C. Das
  • RETINOIC ACID RECEPTOR ANTAGONISTS AS CHAPERONE-MEDIATED AUTOPHAGY MODULATORS AND USES THEREOF
    Publication number: 20190225599
    Abstract: Compounds, compositions and methods are provided for selectively activating chaperone-mediated autophagy (CMA), protecting cells from oxidative stress, proteotoxicity and lipotoxicity, and/or antagonizing activity of retinoic acid receptor alpha (RAR?) in subjects in need thereof.
    Type: Application
    Filed: December 5, 2018
    Publication date: July 25, 2019
    Inventors: Ana Maria CUERVO, Evripidis GAVATHIOTIS, Qisheng XIN, Bhaskar C. DAS
  • Retinoic acid receptor antagonists as chaperone-mediated autophagy modulators and uses thereof
    Patent number: 10189827
    Abstract: Compounds, compositions and methods are provided for selectively activating chaperone-mediated autophagy (CMA), protecting cells from oxidative stress, proteotoxicity and lipotoxicity, and/or antagonizing activity of retinoic acid receptor alpha (RAR?) in subjects in need thereof.
    Type: Grant
    Filed: January 10, 2018
    Date of Patent: January 29, 2019
    Assignee: ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY
    Inventors: Ana Maria Cuervo, Evripidis Gavathiotis, Qisheng Xin, Bhaskar C. Das
  • RETINOIC ACID RECEPTOR ANTAGONISTS AS CHAPERONE-MEDIATED AUTOPHAGY MODULATORS AND USES THEREOF
    Publication number: 20180141937
    Abstract: Compounds, compositions and methods are provided for selectively activating chaperone-mediated autophagy (CMA), protecting cells from oxidative stress, proteotoxicity and lipotoxicity, and/or antagonizing activity of retinoic acid receptor alpha (RAR?) in subjects in need thereof.
    Type: Application
    Filed: January 10, 2018
    Publication date: May 24, 2018
    Applicant: ALBERT EINSTEIN COLLEGE OF MEDICINE, INC.
    Inventors: Ana Maria Cuervo, Evripidis Gavathiotis, Qisheng Xin, Bhaskar C. Das
  • Retinoic acid receptor antagonists as chaperone-mediated authophagy modulators and uses thereof
    Patent number: 9890143
    Abstract: Compounds, compositions and methods are provided for selectively activating chaperone-mediated autophagy (CMA), protecting cells from oxidative stress, proteotoxicity and lipotoxicity, and/or antagonizing activity of retinoic acid receptor alpha (RAR?) in subjects in need thereof.
    Type: Grant
    Filed: October 20, 2016
    Date of Patent: February 13, 2018
    Assignee: Albert Einstein College of Medicine, Inc.
    Inventors: Ana Maria Cuervo, Evripidis Gavathiotis, Qisheng Xin
  • RETINOIC ACID RECEPTOR ANTAGONISTS AS CHAPERONE-MEDIATED AUTHOPHAGY MODULATORS AND USES THEREOF
    Publication number: 20170037039
    Abstract: Compounds, compositions and methods are provided for selectively activating chaperone-mediated autophagy (CMA), protecting cells from oxidative stress, proteotoxicity and lipotoxicity, and/or antagonizing activity of retinoic acid receptor alpha (RAR?) in subjects in need thereof.
    Type: Application
    Filed: October 20, 2016
    Publication date: February 9, 2017
    Applicant: Albert Einstein College of Medicine, Inc.
    Inventors: Ana Maria Cuervo, Evripidis Gavathiotis, Qisheng Xin, Bhaskar C. Das
  • Retinoic acid receptor antagonists as chaperone-mediated autophagy modulators and uses thereof
    Patent number: 9512092
    Abstract: Compounds, compositions and methods are provided for selectively activating chaperone-mediated autophagy (CMA), protecting cells from oxidative stress, proteotoxicity and lipotoxicity, and/or antagonizing activity of retinoic acid receptor alpha (RAR?) in subjects in need thereof.
    Type: Grant
    Filed: December 11, 2014
    Date of Patent: December 6, 2016
    Assignee: ALBERT EINSTEIN COLLEGE OF MEDICINE, INC.
    Inventors: Ana Maria Cuervo, Evripidis Gavathiotis, Qisheng Xin, Bhaskar C. Das
  • RETINOIC ACID RECEPTOR ANTAGONISTS AS CHAPERONE-MEDIATED AUTOPHAGY MODULATORS AND USES THEREOF
    Publication number: 20150166492
    Abstract: Compounds, compositions and methods are provided for selectively activating chaperone-mediated autophagy (CMA), protecting cells from oxidative stress, proteotoxicity and lipotoxicity, and/or antagonizing activity of retinoic acid receptor alpha (RAR?) in subjects in need thereof.
    Type: Application
    Filed: December 11, 2014
    Publication date: June 18, 2015
    Inventors: ANA MARIA CUERVO, EVRIPIDIS GAVATHIOTIS, QISHENG XIN, BHASKAR C. DAS
  • Benzoxazine oxazolidinone compounds, preparation methods and uses thereof
    Patent number: 8507481
    Abstract: Novel benzoxazine oxazolidinone compounds, preparation methods and uses thereof are disclosed, which belong to the field of pharmacy. More specifically, novel benzoxazine oxazolidinone compounds represented by the following general formula (I), preparation methods and uses thereof in preparing medicament for treating infectious diseases, especially infectious diseases caused by multi-drug resistant bacteria, are disclosed.
    Type: Grant
    Filed: May 12, 2011
    Date of Patent: August 13, 2013
    Assignees: Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Nanjing Changao Pharmaceutical Science & Technology Co., Limited
    Inventors: Yushe Yang, Qisheng Xin, Houxing Fan, Bin Guo, Xin Liu, Huili He, Wei Li, Zhan Li
  • NOVEL BENZOXAZINE OXAZOLIDINONE COMPOUNDS, PREPARATION METHODS AND USES THEREOF
    Publication number: 20130123249
    Abstract: Novel benzoxazine oxazolidinone compounds, preparation methods and uses thereof are disclosed, which belong to the field of pharmacy. More specifically, novel benzoxazine oxazolidinone compounds represented by the following general formula (I), preparation methods and uses thereof in preparing medicament for treating infectious diseases, especially infectious diseases caused by multi-drug resistant bacteria, are disclosed.
    Type: Application
    Filed: May 12, 2011
    Publication date: May 16, 2013
    Inventors: Yushe Yang, Qisheng Xin, Houxing Fan, Bin Guo, Xin Liu, Huili He, Wei Li, Zhan Li