Abstract: Provided are compositions for treatment of cancers, including breast cancer, comprising at least one novel daidzein analog, as well as methods of using the same for preventing or treating cancer or tumor growth.

Abstract: Thiazole analog compounds and their pharmaceutically acceptable salts are disclosed, including pharmaceutical compositions comprising the thiazole analog compounds, either alone or in combination with at least one additional therapeutic agent, and/or with a pharmaceutically acceptable carrier. Methods of using the thiazole analog compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of cellular proliferative diseases, such as cancer, are also disclosed.

Abstract: Handling locale information on a computing platform, a computer obtains, in response to an event that an application is pushed to a computing platform, locale information corresponding to the application. The computer determines the type of the application, configures a runtime executable file required by the application according to the locale information corresponding to the application and the type of the application, creates a script for configuring a locale of an operating system on the computing platform consistent with the locale information corresponding to the application, and creates a droplet for the application that includes the configured runtime executable file required by the application and is associated with the created script.

Abstract: Handling locale information on a computing platform in a cloud computing environment. An application pushed by a cloud client is received by a computing platform, in response to receiving a request from a user to execute the application. Locale information associated with the application and the user is retrieved by the computing platform. A script is created and executed by the computing platform to configure a locale of an operating system, and that identifies and installs applications upon which the pushed application depends for execution. A runtime environment, the pushed application, and the applications upon which the pushed application depends for execution in the runtime environment are booted by the computing platform. The pushed application is then executed by the computing platform in the runtime environment.

Abstract: Handling locale information on a computing platform, a computer obtains, in response to an event that an application is pushed to a computing platform, locale information corresponding to the application. The computer determines the type of the application, configures a runtime executable file required by the application according to the locale information corresponding to the application and the type of the application, creates a script for configuring a locale of an operating system on the computing platform consistent with the locale information corresponding to the application, and creates a droplet for the application that includes the configured runtime executable file required by the application and is associated with the created script.

Abstract: A method, system and computer program product for providing a service to multiple tenants of an application. Responsive to receiving from a client of a tenant a request, a tenant context of the tenant is bound to the request. With respect to an access to an isolation point of the application in the request, the access to the isolation point is redirected to a partition based on the tenant context bound to the request. The partition may be pre-established for the tenant with respect to the application. Hence, it is possible to provide a multi-tenant solution in a convenient, fast, and cost-effective way, and, in turn, to achieve resource sharing to a greater extent and enhance the resource efficiency.

Abstract: In various embodiments, a method of controlling a motor and motor control system may be provided. The method may include applying exciting pulse-width-modification (PWM) or continuous sinusoidal voltages to a motor. The method may further include measuring one or more the applied exciting voltages to the motor. The method may further include measuring one or more currents from the motor. The method may also include calculating one or more back electromotive force (BEMF) voltages based on the one or more currents. The method may include adjusting the exciting voltages based on the one or more back electromotive force (BEMF) voltages and the phase angle difference between the calculated back EMF voltages and the measured currents. The motor control system may include the various detecting circuits of the exciting voltages and the motor currents from the motor with low pass filters.

Abstract: The present disclosure relates to boron-based 4-hydroxytamoxifen and endoxifen prodrugs and the synthesis of the same. Further, the present disclosure teaches the utilization of the boron-based 4-hydroxytamoxifen and endoxifen prodrugs in a treatment for breast cancer.

Abstract: Disclosed are daidzein analogs having the formula (I). Also disclosed are compositions, include a disclosed daidzein analogs, methods of preventing or treating bone disease or bone injury and/or stimulating bone growth, in a subject that include administering to the subject an effective amount of disclosed daidzein analog. Disclosed are isolated mesenchymal stem cell that has been altered by treatment a disclosed daidzein analog, daidzein, glycinol, glyceollin I, or glyceollin II, to increase the osteogenic potential of the mesenchymal stem cells.

Abstract: A spindle motor for a hard disk drive includes a base and a bearing assembly coupled to the base. The bearing assembly includes a sleeve configured to rotatably support a shaft therein. A rotor hub is affixed to the shaft so as to be rotatable with the shaft about a rotational axis. A stator is arranged in between the rotor hub and the base. A first magnet is arranged over the stator and on a bottom surface of the rotor hub. In particular, the rotor hub includes a body portion, a peripheral wall portion extending from the body portion in a direction towards the base, and a flange portion having a disk seating surface configured for supporting one or more disks thereon. The peripheral wall portion is configured to at least partially surround the stator in a radial direction. There is also provided a method of fabricating the spindle motor and a hard disk drive incorporating the spindle motor.

Abstract: According to an embodiment of the present invention, a data storage device comprising a motor having a stator is disclosed. The stator may include a substrate having a first surface and a second surface opposite to the first surface; and a n-phase winding arrangement having n phase windings; wherein each phase winding comprises m flat fractional-pitch coils arranged on the first surface of the substrate such that the coils are spaced apart uniformly along a closed loop and connected in series; wherein each coil together with an angular section of the substrate between the coil and an adjacent coil of the same phase winding defines a stator pole-pair; and wherein m is an integer larger than 1.

Abstract: A magnetic disk drive device for rotary driving a magnetic disk may be provided. The magnetic disk drive device may include a drive motor for rotary driving the magnetic disk. The drive motor may include a motor hub which has motor hub support portion with a screw-type motor hub engaging portion, and a motor hub support surface for supporting the magnetic disk. The magnetic disk drive device may also include a clamp disk including a clamp disk support portion with a screw-type clamp disk engaging portion complementary to the motor hub engaging portion, and a clamp disk support surface for supporting the magnetic disk.

Abstract: Thiazole analog compounds and their pharmaceutically acceptable salts are disclosed, including pharmaceutical compositions comprising the thiazole analog compounds, either alone or in combination with at least one additional therapeutic agent, and/or with a pharmaceutically acceptable carrier. Methods of using the thiazole analog compounds, either alone or in combination with at least one additional therapeutic agent, in the prophylaxis or treatment of cellular proliferative diseases, such as cancer, are also disclosed.

Abstract: A spindle motor for a hard disk drive includes a base and a bearing assembly coupled to the base. The bearing assembly includes a sleeve configured to rotatably support a shaft therein. A rotor hub is affixed to the shaft so as to be rotatable with the shaft about a rotational axis. A stator is arranged in between the rotor hub and the base. A first magnet is arranged over the stator and on a bottom surface of the rotor hub. In particular, the rotor hub includes a body portion, a peripheral wall portion extending from the body portion in a direction towards the base, and a flange portion having a disk seating surface configured for supporting one or more disks thereon. The peripheral wall portion is configured to at least partially surround the stator in a radial direction. There is also provided a method of fabricating the spindle motor and a hard disk drive incorporating the spindle motor.

Abstract: According to an embodiment of the present invention, a data storage device comprising a motor having a stator is disclosed. The stator may include a substrate having a first surface and a second surface opposite to the first surface; and a n-phase winding arrangement having n phase windings; wherein each phase winding comprises m flat fractional-pitch coils arranged on the first surface of the substrate such that the coils are spaced apart uniformly along a closed loop and connected in series; wherein each coil together with an angular section of the substrate between the coil and an adjacent coil of the same phase winding defines a stator pole-pair; and wherein m is an integer larger than 1.

Abstract: Provided are compositions for treatment of cancers, including breast cancer, comprising at least one novel daidzein analog, as well as methods of using the same for preventing or treating cancer or tumor growth.

Abstract: The present disclosure relates to boron-based 4-hydroxytamoxifen and endoxifen prodrugs and the synthesis of the same. Further, the present disclosure teaches the utilization of the boron-based 4-hydroxytamoxifen and endoxifen prodrugs in a treatment for breast cancer.

Abstract: Provided are compositions for treatment of cancers, including breast cancer, comprising at least one novel daidzein analog, as well as methods of using the same for preventing or treating cancer or tumor growth.

Abstract: A low profile spindle motor for supporting and rotating media disk or disks of a hard disk drive includes a plurality of stator teeth, a winding layer which may be formed by printed circuit board or the like, and a rotor. The plurality of stator teeth are disposed in an annular region surrounding an axis of rotation of the motor, and have projected ends for increasing the tooth area facing a magnet ring of the rotor. The winding layer has a plurality of windings disposed surrounding the axis of rotation. Each winding is coupled to one of the plurality of stator teeth. The magnet ring is positioned radially spaced apart and coplanar with the annular region. The magnet ring has magnetic poles annularly distributed to generate magnetic fluxes along radial direction. Spindle motor formed according to the invention has a low profile, improved performance and manufacturability.