Patents by Inventor Quang-De Nguyen

Quang-De Nguyen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HER2 polypeptides useful for imaging and monitoring tumors and cancers
    Patent number: 10646600
    Abstract: A method of use of an isolated polypeptide conjugated with a radionuclide, wherein the isolated polypeptide binds specifically to HER2, or a variant thereof is described. The method is for monitoring the response to HSP90 inhibition and comprises the use of the isolated polypeptide conjugated with 18F. The application also describes the use of an isolated polypeptide conjugated with 18F, wherein the isolated polypeptide binds specifically to HER2 or variants thereof, as an imaging agent to monitor uptake thereof to measure HSP90 inhibition.
    Type: Grant
    Filed: June 24, 2014
    Date of Patent: May 12, 2020
    Assignees: IMPERIAL INNOVATIONS LIMITED, GE HEALTHCARE LIMITED
    Inventors: Duncan Robert R. Hiscock, Eric Aboagye, Peter Iveson, Quang-De Nguyen, Susan Hoppmann, Sebastian Trousil, Maciej Kaliszczak, Giampaolo Tomasi
  • USE OF HER2 BINDERS
    Publication number: 20160144062
    Abstract: A method of use of an isolated polypeptide conjugated with a radionuclide, wherein the isolated polypeptide binds specifically to HER2, or a variant thereof is described. The method is for monitoring the response to HSP90 inhibition and comprises the use of the isolated polypeptide conjugated with 18F. The application also describes the use of an isolated polypeptide conjugated with 18F, wherein the isolated polypeptide binds specifically to HER2 or variants thereof, as an imaging agent to monitor uptake thereof to measure HSP90 inhibition.
    Type: Application
    Filed: June 24, 2014
    Publication date: May 26, 2016
    Inventors: Ducan Robert R. HISCOCK, Eric Aboagye, Peter IVESON, Quang-De NGUYEN, Susan HOPPMANN, Sebastian TROUSIL, Maciej KALISZCZAK, Giampaolo TOMASI
  • Isatin derivatives for use as in vivo imaging agents
    Patent number: 8961930
    Abstract: Isatin 5-sulfonamide derivatives, pharmaceutical compositions comprising the derivatives, their use as molecular imaging agents, their use for the diagnosis or treatment of diseases or disorders associated with dysregulation of apoptosis, methods for synthesizing the derivatives, methods for the molecular imaging of caspase activity and apoptosis, and methods of assessing the therapeutic effect of a test substance on caspase activity are disclosed.
    Type: Grant
    Filed: September 4, 2009
    Date of Patent: February 24, 2015
    Assignees: Imperial Innovations Limited, Hammersmith Imanet Limited
    Inventors: Eric Ofori Aboagye, Graham Smith, Quang-De Nguyen, Erik Arstad, Matthias Eberhard Glaser
  • ISATIN DERIVATIVES FOR USE AS IN VIVO IMAGING AGENTS
    Publication number: 20110195024
    Abstract: Isatin 5-sulfonamide derivatives, pharmaceutical compositions comprising the derivatives, their use as molecular imaging agents, their use for the diagnosis or treatment of diseases or disorders associated with dysregulation of apoptosis, methods for synthesizing the derivatives, methods for the molecular imaging of caspase activity and apoptosis, and methods of assessing the therapeutic effect of a test substance on caspase activity are disclosed.
    Type: Application
    Filed: September 4, 2009
    Publication date: August 11, 2011
    Applicants: Imperial Innovations Limited, Hammersmith Imanet Limited
    Inventors: Eric Ofori Aboabye, Graham Smith, Quang-De Nguyen, Erik Arstad, Matthias Eberhard Glaser