Patents by Inventor Quansheng Chen
Quansheng Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240082320Abstract: Provided are Enterococcus lactis, a drug for preventing or treating tumor, and use thereof, relating to the technical field of biomedicines. Novel Enterococcus lactis is separated and chosen, and the Enterococcus lactis has an important influence on the effect of tumor immunotherapy for cancer patients. Gut microorganisms and immune cells can interact with each other to jointly regulate the human immune system. The provided Enterococcus lactis can induce the differentiation and maturation of iDC (immature DC) cells, and mature DC can effectively activate T cells and increase the infiltration of tumor infiltrating lymphocytes having anti-tumor activity, thereby killing tumor cells. In addition, the provided Enterococcus lactis can induce the differentiation of M0 type macrophages into M1 or M2 type cells.Type: ApplicationFiled: June 8, 2021Publication date: March 14, 2024Inventors: Baoxia Li, Quansheng Lin, Yibo Xian, Xianzhi Jiang, Jiening Liang, Zhenzhen Liu, Sheng Chen, Xue Su
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Publication number: 20240075474Abstract: A biosensing platform for in-situ sampling and target detection based on upconversion luminescence, including: an upconversion luminescent paper-based microfluidic device, an upconversion luminescent biosensor, and a portable detection device based on smartphone imaging. The upconversion luminescent paper-based microfluidic device is configured to sample a to-be-detected substance in situ. The upconversion luminescent biosensor is configured to allow a target to specifically recognize the to-be-detected substance. The portable detection device is configured to detect a content of the to-be-detected substance. The upconversion luminescent biosensor is prepared as follows. (S1) An upconversion nanoparticle seed is prepared. (S2) Core-shell upconversion nanoparticles are prepared. (S3) Core-shell-shell upconversion nanoparticles (UCNPs) are prepared. (S4) The UCNPs is subjected to hydrophilic modification. (S5) The hydrophilically-modified UCNPs are modified with DNA.Type: ApplicationFiled: October 31, 2023Publication date: March 7, 2024Inventors: Quansheng CHEN, Jizhong WU, Qin OUYANG, Wenya WEI, Huanhuan LI, Jingui ZHANG, Jinghao YU
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Publication number: 20240017257Abstract: A microfluidic biosensing platform based on upconversion luminescence, including: an upconversion luminescence biosensor for specifically recognizing EDCs and a microfluidic chip. The microfluidic chip includes a sample injection pool, a biosensor injection pool, an arc-shaped channel, a separation channel and a detection pool. An inlet of the arc-shaped channel is communicated with the sample injection pool and the biosensor injection pool, and is configured for mixing and reacting the biosensor with the sample. The separation channel is communicated with an outlet of the arc-shaped channel, and is configured for magnetic separation of the biosensor. The detection pool is communicated with the outlet of the separation channel, and is configured for completing the enhanced luminescence-based quantitative detection of EDCs.Type: ApplicationFiled: September 4, 2023Publication date: January 18, 2024Inventors: Quansheng CHEN, Jizhong WU, Qin OUYANG, Wenya WEI, Songguang ZHAO, Afang ZHU, Zhen WANG
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Patent number: 11773322Abstract: A method of preparing a dye-functionalized flexible upconversion-luminescence solid-phase sensor, including: preparation of upconversion-luminescence nanoparticles, preparation of an upconversion nanoparticle-doped solid-phase sensor, and preparation of a dye-functionalized flexible upconversion-luminescence solid-phase sensor. A method for detecting a gaseous pollutant is also provided, including: preparing a dye-functionalized flexible upconversion-luminescence solid-phase sensor through the above method; establishing a prediction model; and substituting a fluorescence intensity of a sample into the prediction model to calculate the gaseous pollutant concentration in the sample.Type: GrantFiled: April 28, 2023Date of Patent: October 3, 2023Assignee: JIANGSU UNIVERSITYInventors: Quansheng Chen, Jizhong Wu, Huanhuan Li, Jingui Zhang, Hao Lin, Haihui Pan, Fuyun Wang, Yue Liang, Aijuan Ma, Tianyu Cao, Xiafei Xu, Huanke Hou
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Publication number: 20230265341Abstract: A method of preparing a dye-functionalized flexible upconversion-luminescence solid-phase sensor, including: preparation of upconversion-luminescence nanoparticles, preparation of an upconversion nanoparticle-doped solid-phase sensor, and preparation of a dye-functionalized flexible upconversion-luminescence solid-phase sensor. A method for detecting a gaseous pollutant is also provided, including: preparing a dye-functionalized flexible upconversion-luminescence solid-phase sensor through the above method; establishing a prediction model; and substituting a fluorescence intensity of a sample into the prediction model to calculate the gaseous pollutant concentration in the sample.Type: ApplicationFiled: April 28, 2023Publication date: August 24, 2023Inventors: Quansheng CHEN, Jizhong WU, Huanhuan LI, Jingui ZHANG, Hao LIN, Haihui PAN, Fuyun WANG, Yue LIANG, Aijuan MA, Tianyu CAO, Xiafei XU, Huanke HOU
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Publication number: 20230266249Abstract: A characteristic information extraction method of a small-molecule volatile substance, including: dividing a surface-enhanced Raman scattering (SERS) spectrum of the small-molecule volatile substance to obtain n wavelength subintervals, where n is a positive integer; sampling the n wavelength subintervals through weighted bootstrap sampling (WBS) to obtain Wwavelength subintervals, where W is a positive integer less than n; and screening the W wavelength subintervals to obtain desired wavelength subintervals. This application also provides a rapid detection method and a portable detection system of a small-molecule volatile substance.Type: ApplicationFiled: April 28, 2023Publication date: August 24, 2023Inventors: Quansheng CHEN, Huanhuan LI, Qin OUYANG, Jiaji ZHU, Yi XU, Tianhui JIAO, Haihui PAN
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Patent number: 11635385Abstract: A method for fast extracting an organic pollutant in a complex system is disclosed, which includes following steps. A surface-enhanced Raman scattering (SERS) spectrum of an organic pollutant is divided to obtain P wavelength sub-intervals with overlapping regions. The P wavelength sub-intervals are screened to obtain ? wavelength sub-intervals. The ? wavelength sub-intervals are screened to obtain a required wavelength sub-interval. The required wavelength sub-interval is screened to obtain a required wavelength subset. A method and a system for fast detecting an organic pollutant in a complex system are also disclosed.Type: GrantFiled: October 20, 2021Date of Patent: April 25, 2023Assignees: JiMei University, Jiangsu UniversityInventors: Quansheng Chen, Huanhuan Li, Qin Ouyang, Jiaji Zhu, Yi Xu, Tianhui Jiao, Haihui Pan
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Publication number: 20220042918Abstract: A method for fast extracting an organic pollutant in a complex system is disclosed, which includes following steps. A surface-enhanced Raman scattering (SERS) spectrum of an organic pollutant is divided to obtain P wavelength sub-intervals with overlapping regions. The P wavelength sub-intervals are screened to obtain ? wavelength sub-intervals. The ? wavelength sub-intervals are screened to obtain a required wavelength sub-interval. The required wavelength sub-interval is screened to obtain a required wavelength subset. A method and a system for fast detecting an organic pollutant in a complex system are also disclosed.Type: ApplicationFiled: October 20, 2021Publication date: February 10, 2022Inventors: Quansheng CHEN, Huanhuan LI, Qin OUYANG, Jiaji ZHU, Yi XU, Tianhui JIAO, Haihui PAN
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Publication number: 20220026357Abstract: The invention discloses a portable visible/near-infrared spectrum detection device, comprising a housing, a bottom plate, a screen support frame, a battery part on which a microprocessor is arranged, a detection part and a switch part, wherein the battery part, the detection part and the switch part are arranged in the housing; and the detection part comprises a spectrometer, a light source, a collimating mirror and the microprocessor. The device has the characteristics of rapidness, no damage and portability, and can realize rapid detection and early warning of food quality.Type: ApplicationFiled: May 25, 2021Publication date: January 27, 2022Inventors: Qin Ouyang, Li Wang, Quansheng Chen, Zhiming Guo, Huanhuan Li, Jizhong Wu, Haihui Pan
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Publication number: 20160366903Abstract: The invention involves a method and a device that converting the summer-autumn tea concentrate to instant powdered black tea by oxidation reaction. The method is comprised of the following steps: pushing the summer-autumn tea concentrate and oxygen into a long spiral pipe, making them flow, impact, and mix in a high speed which can achieve a high efficient oxidation; the intelligent control of the oxidation process can be realized by the change of the color of the concentrate in the oxidation process; the color value of the concentrate can be detected in real time by peristalsis pump, which flows into the color detection channel based on the multi spectral flash LED light transmission technology; the oxidation can be stopped immediately when the detected chromatic value is within the range of the preset target chromatic value. The patent also provides a device for aerating oxygen, including summer-autumn tea concentrate liquid storage tank, gas-liquid mixing pipe loop and color pipeline detection circuit.Type: ApplicationFiled: April 29, 2015Publication date: December 22, 2016Applicant: Jiangsu UniversityInventors: Quansheng CHEN, Dongliang ZHANG, Qin OUYANG, Pengxiang YUE, Jiewen ZHAO
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Patent number: 9347029Abstract: A multi-sensor based automatic brewing mass overturn machine comprising a moving module, a vinegar brewing mass information monitoring module, a system control module and a brewing mass overturn execution module is provided. The moving module comprises a moving motor, and the vinegar brewing mass information monitoring module comprises a vinegar brewing mass temperature and acidity information monitoring unit, a vinegar brewing mass smell information monitoring unit, and an overturned brewing mass appearance information monitoring unit. The system control module comprises a computer and a programmable controller, the computer being connected with a temperature sensor, an acidity sensor, a gas sensor array, a color camera and the programmable controller, respectively. The brewing mass overturn execution module comprises an overturn motor and brewing mass overturn motors.Type: GrantFiled: November 28, 2012Date of Patent: May 24, 2016Assignee: JIANGSU UNIVERSITYInventors: Xiaobo Zou, Jiyong Shi, Jiewen Zhao, Zongbao Sun, Rong Xia, Leliu Sun, Xiaowei Huang, Xingyi Huang, Jianrong Cai, Quansheng Chen, Hao Lin
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Publication number: 20140245896Abstract: A multi-sensor based automatic brewing mass overturn machine comprising a moving module, a vinegar brewing mass information monitoring module, a system control module and a brewing mass overturn execution module is provided. The moving module comprises a moving motor, and the vinegar brewing mass information monitoring module comprises a vinegar brewing mass temperature and acidity information monitoring unit, a vinegar brewing mass smell information monitoring unit, and an overturned brewing mass appearance information monitoring unit. The system control module comprises a computer and a programmable controller, the computer being connected with a temperature sensor, an acidity sensor, a gas sensor array, a color camera and the programmable controller, respectively. The brewing mass overturn execution module comprises an overturn motor and brewing mass overturn motors.Type: ApplicationFiled: November 28, 2012Publication date: September 4, 2014Applicant: JIANGSU UNIVERSITYInventors: Xiaobo Zou, Jiyong Shi, Jiewen Zhao, Zongbao Sun, Rong Xia, Leliu Sun, Xiaowei Huang, Xingyi Huang, Jianrong Cai, Quansheng Chen, Hao Lin
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Patent number: 8564769Abstract: A hyperspectral imaging light source system includes a light box (1). The light box (1) is a sealed cuboid. In the chamber of the box body a line-scanning camera (2), a beam splitting system (3), an electric control translation platform carrier (5) and the object to be detected (4) on the electric control translation platform carrier, an electric control translation platform screw (6), a linear light source box (7) and a photosensitive diode (8) are respectively provided. A linear light source controller (9), a step motor (10) and a computer (11) are provided outside the box body. The photosensitive diode (8) senses linear light source intensity variation and inputs a feedback signal to the linear light source controller (9). A halogen lamp (13) is installed in the linear light source box (7), and is connected with the linear light source controller (9).Type: GrantFiled: May 24, 2010Date of Patent: October 22, 2013Assignee: Jiangsu UniversityInventors: Xiaobo Zou, Jiyong Shi, Jiewen Zhao, Xiaoping Yin, Zhengwei Chen, Xingyi Huang, Jianrong Cai, Quansheng Chen
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Publication number: 20130201350Abstract: A hyperspectral imaging light source system includes a light box (1). The light box (1) is a sealed cuboid. In the chamber of the box body a line-scanning camera (2), a beam splitting system (3), an electric control translation platform carrier (5) and the object to be detected (4) on the electric control translation platform carrier, an electric control translation platform screw (6), a linear light source box (7) and a photosensitive diode (8) are respectively provided. A linear light source controller (9), a step motor (10) and a computer (11) are provided outside the box body. The photosensitive diode (8) senses linear light source intensity variation and inputs a feedback signal to the linear light source controller (9). A halogen lamp (13) is installed in the linear light source box (7), and is connected with the linear light source controller (9).Type: ApplicationFiled: May 24, 2010Publication date: August 8, 2013Applicant: JIANGSU UNIVERSITYInventors: Xiaobo Zou, Jiyong Shi, Jiewen Zhao, Xiaoping Yin, Zhengwei Chen, Xingyi Huang, Jianrong Cai, Quansheng Chen