Patents by Inventor Qun Zhong
Qun Zhong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20160281140Abstract: The invention generally relates to methods and systems for manipulating droplet size. In certain aspects, the invention provides methods for manipulating droplet size that include forming droplets of aqueous fluid surrounded by an immiscible carrier fluid, and manipulating droplet size during the forming step by adjusting pressure exerted on the aqueous fluid or the carrier fluid.Type: ApplicationFiled: June 8, 2016Publication date: September 29, 2016Inventors: Benjamin J. Miller, Qun Zhong, Darren Roy Link
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Patent number: 9441266Abstract: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.Type: GrantFiled: February 22, 2013Date of Patent: September 13, 2016Assignee: Raindance Technologies, Inc.Inventors: Jonathan William Larson, Qun Zhong, Darren Roy Link
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Publication number: 20160222433Abstract: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.Type: ApplicationFiled: February 9, 2016Publication date: August 4, 2016Inventors: Jonathan William Larson, Qun Zhong, Darren R. Link
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Publication number: 20160209303Abstract: The invention provides methods for assessing one or more predetermined characteristics or properties of a microfluidic droplet within a microfluidic channel, and regulating one or more fluid flow rates within that channel to selectively alter the predetermined microdroplet characteristic or property using a feedback control.Type: ApplicationFiled: March 28, 2016Publication date: July 21, 2016Inventors: Benjamin Miller, Brian Hutchison, Andrew Wilson, Jonathan William Larson, Qun Zhong, Yevgeny Yurkovetsky, Darren Link, Mark Weary
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Patent number: 9366632Abstract: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.Type: GrantFiled: April 19, 2013Date of Patent: June 14, 2016Assignee: Raindance Technologies, Inc.Inventors: Darren R. Link, Qun Zhong, Andrew Watson
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Patent number: 9341594Abstract: The invention provides methods for assessing one or more predetermined characteristics or properties of a microfluidic droplet within a microfluidic channel, and regulating one or more fluid flow rates within that channel to selectively alter the predetermined microdroplet characteristic or property using a feedback control.Type: GrantFiled: October 10, 2014Date of Patent: May 17, 2016Assignee: Raindance Technologies, Inc.Inventors: Benjamin J. Miller, Brian Hutchison, Andrew Wilson, Jonathan William Larson, Qun Zhong, Yevgeny Yurkovetsky, Darren R. Link, Mark Weary
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Patent number: 9127310Abstract: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.Type: GrantFiled: April 29, 2014Date of Patent: September 8, 2015Inventors: Jonathan William Larson, Qun Zhong, Darren R. Link
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Patent number: 9074242Abstract: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.Type: GrantFiled: February 11, 2011Date of Patent: July 7, 2015Assignee: Raindance Technologies, Inc.Inventors: Jonathan William Larson, Qun Zhong, Darren Roy Link
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Publication number: 20150027892Abstract: The invention provides methods for assessing one or more predetermined characteristics or properties of a microfluidic droplet within a microfluidic channel, and regulating one or more fluid flow rates within that channel to selectively alter the predetermined microdroplet characteristic or property using a feedback control.Type: ApplicationFiled: October 10, 2014Publication date: January 29, 2015Inventors: Benjamin J. Miller, John Brian Hutchison, Andrew Wilson, Jonathan William Larson, Qun Zhong, Yevgeny Yurkovetsky, Darren R. Link, Mark Weary
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Publication number: 20140329239Abstract: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.Type: ApplicationFiled: April 29, 2014Publication date: November 6, 2014Applicant: RAINDANCE TECHNOLOGIES, INC.Inventors: Jonathan William Larson, Qun Zhong, Darren R. Link
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Patent number: 8857462Abstract: The invention provides methods for assessing one or more predetermined characteristics or properties of a microfluidic droplet within a microfluidic channel, and regulating one or more fluid flow rates within that channel to selectively alter the predetermined microdroplet characteristic or property using a feedback control.Type: GrantFiled: September 9, 2013Date of Patent: October 14, 2014Assignee: Raindance Technologies, Inc.Inventors: Benjamin Miller, Brian Hutchison, Andrew Wilson, Jonathan Larson, Qun Zhong, Yevgeny Yurkovetsky, Darren Link, Mark Weary
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Patent number: 8838765Abstract: A computer-implemented process provides for intercepting a request from a management tool running on a management system. The request can be for a management tool to run on a managed system. Plural virtual consoles are created for the managed system. The original request is modified to generate a modified request that specifies that plural data types generated by said management tool are to be directed to different respective ones of said virtual consoles.Type: GrantFiled: December 14, 2009Date of Patent: September 16, 2014Assignee: Hewlett-Packard Development Company, L.P.Inventor: Qun Zhong
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Publication number: 20140154695Abstract: The invention generally relates to methods and systems for manipulating droplet size. In certain aspects, the invention provides methods for manipulating droplet size that include forming droplets of aqueous fluid surrounded by an immiscible carrier fluid, and manipulating droplet size during the forming step by adjusting pressure exerted on the aqueous fluid or the carrier fluid.Type: ApplicationFiled: February 6, 2014Publication date: June 5, 2014Applicant: Raindance Technologies, Inc.Inventors: Benjamin J. Miller, Qun Zhong, Darren Roy Link
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Publication number: 20140076430Abstract: The invention provides methods for assessing one or more predetermined characteristics or properties of a microfluidic droplet within a microfluidic channel, and regulating one or more fluid flow rates within that channel to selectively alter the predetermined microdroplet characteristic or property using a feedback control.Type: ApplicationFiled: September 9, 2013Publication date: March 20, 2014Applicant: RAINDANCE TECHNOLOGIES, INC.Inventors: Benjamin Miller, Brian Hutchison, Andrew Wilson, Jonathan Larson, Qun Zhong, Yevgeny Yurkovetsky, Darren Link, Mark Weary
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Patent number: 8658430Abstract: The invention generally relates to methods and systems for manipulating droplet size. In certain aspects, the invention provides methods for manipulating droplet size that include forming droplets of aqueous fluid surrounded by an immiscible carrier fluid, and manipulating droplet size during the forming step by adjusting pressure exerted on the aqueous fluid or the carrier fluid.Type: GrantFiled: July 20, 2012Date of Patent: February 25, 2014Assignee: Raindance Technologies, Inc.Inventors: Benjamin J. Miller, Qun Zhong, Darren Roy Link
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Publication number: 20130295567Abstract: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.Type: ApplicationFiled: April 19, 2013Publication date: November 7, 2013Inventors: Darren Roy Link, Qun Zhong, Andrew Watson
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Patent number: 8535889Abstract: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.Type: GrantFiled: February 11, 2011Date of Patent: September 17, 2013Assignee: Raindance Technologies, Inc.Inventors: Jonathan William Larson, Qun Zhong, Darren Roy Link
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Patent number: 8528589Abstract: The invention provides methods for assessing one or more predetermined characteristics or properties of a microfluidic droplet within a microfluidic channel, and regulating one or more fluid flow rates within that channel to selectively alter the predetermined microdroplet characteristic or property using a feedback control.Type: GrantFiled: March 23, 2010Date of Patent: September 10, 2013Assignee: Raindance Technologies, Inc.Inventors: Benjamin Miller, Brian Hutchison, Andrew Wilson, Jonathan Larson, Qun Zhong, Yevgeny Yurkovetsky, Darren Link, Mark Weary
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Publication number: 20130196324Abstract: The invention generally relates to droplet based digital PCR and methods for analyzing a target nucleic acid using the same. In certain embodiments, methods of the invention involve forming sample droplets containing, on average, a single target nucleic acid, amplifying the target in the droplets, excluding droplets containing amplicon from the target and amplicon from a variant of the target, and analyzing target amplicons.Type: ApplicationFiled: February 22, 2013Publication date: August 1, 2013Inventors: Jonathan William Larson, Qun Zhong, Darren Roy Link
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Publication number: 20130099018Abstract: The invention generally relates to methods and systems for manipulating droplet size. In certain aspects, the invention provides methods for manipulating droplet size that include forming droplets of aqueous fluid surrounded by an immiscible carrier fluid, and manipulating droplet size during the forming step by adjusting pressure exerted on the aqueous fluid or the carrier fluid.Type: ApplicationFiled: July 20, 2012Publication date: April 25, 2013Applicant: Raindance Technolgies, Inc.Inventors: Benjamin J. Miller, Qun Zhong, Darren Roy Link