Patents by Inventor Quyen T Nguyen

Quyen T Nguyen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240124523
    Abstract: The present invention provides methods for guiding preservation of human neurons or human nerves during surgery by administering a fluorescently-labeled peptide that specifically binds to the human neurons or human nerves. The invention further provides human neuron or nerve targeting molecules comprising fluorescently-labeled peptides that specifically bind to human neurons or human nerves and compositions thereof.
    Type: Application
    Filed: August 30, 2023
    Publication date: April 18, 2024
    Inventors: Quyen T. Nguyen, Mike Whitney, Dina Hingorani, Roger Y. Tsien, Stephen Adams
  • Patent number: 11802138
    Abstract: The present invention provides methods for guiding preservation of human neurons or human nerves during surgery by administering a fluorescently-labeled peptide that specifically binds to the human neurons or human nerves. The invention further provides human neuron or nerve targeting molecules comprising fluorescently-labeled peptides that specifically bind to human neurons or human nerves and compositions thereof.
    Type: Grant
    Filed: May 21, 2021
    Date of Patent: October 31, 2023
    Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Quyen T. Nguyen, Mike Whitney, Dina Hingorani, Roger Y. Tsien, Stephen Adams
  • Patent number: 11299515
    Abstract: The present invention provides methods for guiding preservation of human neurons or human nerves during surgery by administering a fluorescently-labeled peptide that specifically binds to the human neurons or human nerves. The invention further provides human neuron or nerve targeting molecules comprising fluorescently-labeled peptides that specifically bind to human neurons or human nerves and compositions thereof.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: April 12, 2022
    Assignee: The Regents of the University of California
    Inventors: Quyen T. Nguyen, Mike Whitney, Dina Hingorani, Roger Y. Tsien, Stephen Adams
  • Publication number: 20210363186
    Abstract: The present invention provides methods for guiding preservation of human neurons or human nerves during surgery by administering a fluorescently-labeled peptide that specifically binds to the human neurons or human nerves. The invention further provides human neuron or nerve targeting molecules comprising fluorescently-labeled peptides that specifically bind to human neurons or human nerves and compositions thereof.
    Type: Application
    Filed: May 21, 2021
    Publication date: November 25, 2021
    Inventors: Quyen T. Nguyen, Mike Whitney, Dina Hingorani, Roger Y. Tsien, Stephen Adams
  • Patent number: 11021517
    Abstract: The present invention provides methods for guiding preservation of human neurons or human nerves during surgery by administering a fluorescently-labeled peptide that specifically binds to the human neurons or human nerves. The invention further provides human neuron or nerve targeting molecules comprising fluorescently-labeled peptides that specifically bind to human neurons or human nerves and compositions thereof.
    Type: Grant
    Filed: February 3, 2020
    Date of Patent: June 1, 2021
    Assignee: The Regents of the University of California
    Inventors: Quyen T. Nguyen, Mike Whitney, Dina Hingorani, Roger Y. Tsien, Stephen Adams
  • Publication number: 20210087229
    Abstract: The present invention provides methods for guiding preservation of human neurons or human nerves during surgery by administering a fluorescently-labeled peptide that specifically binds to the human neurons or human nerves. The invention further provides human neuron or nerve targeting molecules comprising fluorescently-labeled peptides that specifically bind to human neurons or human nerves and compositions thereof.
    Type: Application
    Filed: August 2, 2018
    Publication date: March 25, 2021
    Inventors: Quyen T. Nguyen, Micheal A. Whitney, Dina Hingorani, Roger Y. Tsien, Stephen Adams
  • Publication number: 20200239522
    Abstract: The present invention provides methods for guiding preservation of human neurons or human nerves during surgery by administering a fluorescently-labeled peptide that specifically binds to the human neurons or human nerves. The invention further provides human neuron or nerve targeting molecules comprising fluorescently-labeled peptides that specifically bind to human neurons or human nerves and compositions thereof.
    Type: Application
    Filed: February 3, 2020
    Publication date: July 30, 2020
    Inventors: Quyen T. Nguyen, Mike Whitney, Dina Hingorani, Roger Y. Tsien, Stephen Adams
  • Patent number: 10385380
    Abstract: Disclosed herein, the invention pertains to methods and compositions that find use in diagnostic, prognostic and characterization of neoplasia samples based on the ability of a neoplasia sample to cleave a MTS molecule of the present invention. In some embodiments, a MTS molecule disclosed herein has the formula (A-X-B-C), wherein A is a peptide with a sequence comprising 5 to 9 consecutive acidic amino acids, wherein the amino acids are selected from: aspartates and glutamates; B is a peptide with a sequence comprising 5 to 20 consecutive basic amino acids; X is a linker; and C is a detectable moiety.
    Type: Grant
    Filed: October 2, 2015
    Date of Patent: August 20, 2019
    Assignee: The Regents of the University of California
    Inventors: Mike Whitney, Quyen T. Nguyen, Roger Y. Tsien
  • Publication number: 20190175021
    Abstract: Imaging systems for fluorescence guided surgery are provided. An imaging system comprises a light source unit for providing one or more illumination and excitation lights to a target, a detection unit for detecting reflectance and fluorescence from the target, an optical train for directing the one or more illumination and excitation lights from the light source unit to the target and for directing the reflectance and fluorescence from the target to the detection unit, and a control unit for controlling the light source unit and the detection unit. Imaging methods for fluorescence guided surgery are also provided.
    Type: Application
    Filed: October 10, 2018
    Publication date: June 13, 2019
    Inventors: Paul Steinbach, Quyen T. Nguyen, Roger Y. Tsien
  • Patent number: 10231626
    Abstract: Imaging systems for fluorescence guided surgery are provided. An imaging system comprises a light source unit for providing one or more illumination and excitation lights to a target, a detection unit for detecting reflectance and fluorescence from the target, an optical train for directing the one or more illumination and excitation lights from the light source unit to the target and for directing the reflectance and fluorescence from the target to the detection unit, and a control unit for controlling the light source unit and the detection unit. Imaging methods for fluorescence guided surgery are also provided.
    Type: Grant
    Filed: March 17, 2014
    Date of Patent: March 19, 2019
    Assignee: The Regents of the University of California
    Inventors: Paul Steinbach, Quyen T. Nguyen, Roger Y. Tsien
  • Publication number: 20160160263
    Abstract: Disclosed herein, the invention pertains to methods and compositions that find use in diagnostic, prognostic and characterization of neoplasia samples based on the ability of a neoplasia sample to cleave a MTS molecule of the present invention. In some embodiments, a MTS molecule disclosed herein has the formula (A-X-B-C), wherein A is a peptide with a sequence comprising 5 to 9 consecutive acidic amino acids, wherein the amino acids are selected from: aspartates and glutamates; B is a peptide with a sequence comprising 5 to 20 consecutive basic amino acids; X is a linker; and C is a detectable moiety.
    Type: Application
    Filed: October 2, 2015
    Publication date: June 9, 2016
    Inventors: Mike Whitney, Quyen T. Nguyen, Roger Y. Tsien
  • Publication number: 20160095374
    Abstract: A single section lift-up technique for eyelash extensions with curved tweezers. Place three pieces of surgical tape over upper natural eyelashes to divide the eyelid into an outer corner, a middle and an inner corner section. Lift up the upper eyelashes one at a time from under the surgical tape on each section with a curved tweezers. Attach adhesive coated false eyelashes one at a time against the upper lashes of the each section with the curved tweezers. Attach adhesive coded false eyelashes one at a time against the upper eyelashes of each section with the curved tweezers.
    Type: Application
    Filed: October 6, 2014
    Publication date: April 7, 2016
    Inventor: QUYEN T. NGUYEN
  • Publication number: 20140276008
    Abstract: Imaging systems for fluorescence guided surgery are provided. An imaging system comprises a light source unit for providing one or more illumination and excitation lights to a target, a detection unit for detecting reflectance and fluorescence from the target, an optical train for directing the one or more illumination and excitation lights from the light source unit to the target and for directing the reflectance and fluorescence from the target to the detection unit, and a control unit for controlling the light source unit and the detection unit. Imaging methods for fluorescence guided surgery are also provided.
    Type: Application
    Filed: March 17, 2014
    Publication date: September 18, 2014
    Applicant: The Regents of the University of California
    Inventors: Paul Steinbach, Quyen T. Nguyen, Roger Y. Tsien
  • Patent number: 8685372
    Abstract: The present invention provides methods for guiding preservation of neurons or nerves during surgery by administering a fluorescently-labeled peptide or aptamer that specifically binds to the neurons or nerves. The invention further provides targeting molecules of fluorescently-labeled peptides or aptamers that specifically bind to neurons or nerves and for compositions thereof.
    Type: Grant
    Filed: April 15, 2010
    Date of Patent: April 1, 2014
    Assignee: The Regents of the University of California
    Inventors: Roger Y. Tsien, Quyen T. Nguyen, Michael Whitney
  • Publication number: 20120148499
    Abstract: The present invention provides methods for guiding preservation of neurons or nerves during surgery by administering a fluorescently-labeled peptide or aptamer that specifically binds to the neurons or nerves. The invention further provides targeting molecules of fluorescently-labeled peptides or aptamers that specifically bind to neurons or nerves and for compositions thereof.
    Type: Application
    Filed: April 15, 2010
    Publication date: June 14, 2012
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Roger Y. Tsien, Quyen T. Nguyen, Michael Whitney
  • Patent number: 8113218
    Abstract: A method to apply a V-shaped eyelash having four symmetric tapered strands attached at the mounting portion to natural eyelash's hair. The V-shaped eyelash has two strands on each side. The V flare corresponds to an angle can be less than or equal to 160° degrees. The thickness of each strand can be 0.10 mm to 0.30 mm thick at the base and tapered at the tips. The lengths can be from 7 mm to 17 mm giving the illusion of a natural long, beautiful and luscious eyelash. Because the eyelash extension is a V shape with the two strands on each side, the eyelash can distribute weight evenly on each side. The natural hair strand as the holder at center also making the eyelash extensions last longer. The eyelashes are made from synthetic fiber which is crimp free and can be permed to a C, and J curl.
    Type: Grant
    Filed: January 8, 2009
    Date of Patent: February 14, 2012
    Inventor: Quyen T Nguyen