Abstract: Methods, apparatuses, and systems related to managing operations performed in response to refresh management (RFM) commands. A controller generates the RFM command for coordinating a refresh management operation targeted for implementation at an apparatus. The apparatus tracks refresh target set that includes refresh management target locations within the apparatus. According to the tracked refresh management target set, the apparatus selectively implements the targeted refresh management operation and/or a response operation in addition to or as a replacement for the targeted refresh management operation.

Abstract: A fire protection sprinkler including a frame body having an inlet, an outlet, defining an internal passageway extending between the inlet and the outlet along a sprinkler axis. A dome shaped deflector member is centered, axially aligned with the sprinkler axis, and spaced from the outlet. The deflector member has an outer surface and an inner surface that preferably includes: a peripheral region, a central region and an intermediate region. The intermediate region includes a primary deflecting surface, and a secondary deflecting surface that is surrounded by the primary deflecting surface. The deflector member provides for generation of a non-circular spray pattern defined by four zones of fluid density concentrically formed about the sprinkler axis.

Abstract: A sterile drape assembly for a surgical system can comprise a sterile drape and a cinch assembly affixed to the sterile drape. A surgical support system can include a manipulator arm assembly comprising a first manipulator link extending between opposite ends; a drape guide lip extending from one end of the opposite ends of the first actively controlled manipulator link; and a second manipulator link coupled to the first manipulator link wherein the drape guide lip is a barrier between contact of a first drape portion covering the second manipulator link with a second drape portion covering the first manipulator link.

Abstract: A system includes an algae bioreactor that contains an algae slurry, a heat exchanger in fluid communication with the algae bioreactor to receive the algae slurry from the algae bioreactor and heat and increase a pressure of the algae slurry, and one or more valves and a flash vessel in fluid communication with a discharge of the heat exchanger to flash the algae slurry and create steam and algae biomass. A separator receives the algae biomass from the flash vessel and separates oils from the algae biomass to generate a biofuel.

Abstract: A fitting includes a first and second threaded fitting component and a conduit gripping device receivable within the first threaded fitting component. A stroke resisting member is integral with the first threaded fitting component and includes a web having a first radial thickness and extending axially inward from the first threaded fitting component to a distal ring portion having a second radial thickness greater than the first radial thickness. A radially extending bearing surface of the distal ring portion axially engages a radially extending portion of the second fitting component when the first and second fitting components are joined together to the first relative axial position. The stroke resisting member resists additional axial stroke of the first and second fitting components, such that a tightening torque beyond the first relative axial position is increased by the axial engagement.

Abstract: Devices, systems, and techniques are described to detect when a power transmitting and receiving system is in an inefficient position, which may cause a thermal response that less desirable than a more efficient position. The system may power transmitting device configured to wirelessly transfer electromagnetic energy to a power receiving device. Processing circuitry of the system may compute a target output power deliverable by the power transmitting device for a first duration and control the power transmitting device to output the target output power based in part on a heat limit. The processing circuitry may further calculate an energy transfer efficiency to the power receiving unit, update an adjustment factor based on the calculated energy transfer efficiency, and apply the adjustment factor to the heat limit for a subsequent duration.

Abstract: A check valve includes a valve element and a valve body having a body housing, an annular valve seat insert, a bushing, and a biasing member. The body housing includes an outer circumferential wall extending between an inlet port and an outlet port to define a valve cavity therebetween. The valve seat insert is seated in a body seat surface surrounding the inlet port. The bushing is disposed in the valve cavity and defines a central bore, with the bushing including an outboard end surface axially engageable with the valve seat insert. The biasing member is disposed between a bearing portion of the body housing and an inboard end of the bushing to allow for axial movement of the bushing with respect to the body seat surface. The valve element extends through the bushing central bore and is movable between a closed position and an open position.

Abstract: The disclosure provides adenosine deaminases that are capable of deaminating adenosine in DNA to treat Hutchin-son-Gilford progeria syndrome (HOPS). The disclosure also provides fusion proteins, guide RNAs and compositions comprising a Cas9 (e.g., a Cas9 nickase) domain and adenosine deaminases that deaminate adenosine in DNA, for example in a LNA gene. In some embodiments, adenosine deaminases provided herein are used to correct a C1824T mutation in LMNA. In some embodiments, the methods and compositions provided herein are used to treat Hutchinson-Gilford progeria syndrome (HGPS).

Abstract: A surface cleaning head includes a housing having a front side and back side, a brush roll rotatably mounted to the housing within a suction conduit and having at least a portion proximate the opening of the suction conduit, a leading roller mounted to the housing in front of the brush roll, and a drive mechanism operatively coupled to the brush roll and the leading roller for driving the brush roll and the leading roller at same time. The brush roll includes an agitator body and a first bristle/flap arrangement comprising a first deformable flap extending from the agitator body and a first bristle strip and/or row of tufts extending from the agitator body and disposed adjacent to the first deformable flap. The first deformable flap is disposed at an aggressive angle and the first bristle strip and/or row of tufts is arranged at a passive angle.

Abstract: A surface cleaning head includes a housing having a front side and back side, a brush roll rotatably mounted to the housing within a suction conduit and having at least a portion proximate the opening of the suction conduit, a leading roller mounted to the housing in front of the brush roll, and a drive mechanism operatively coupled to the brush roll and the leading roller for driving the brush roll and the leading roller at same time. The brush roll includes an agitator body and a first bristle/flap arrangement comprising a first deformable flap extending from the agitator body and a first bristle strip and/or row of tufts extending from the agitator body and disposed adjacent to the first deformable flap. The first deformable flap is disposed at an aggressive angle and the first bristle strip and/or row of tufts is arranged at a passive angle.

Abstract: A valve repair device for repairing a native valve of a patient. The valve repair device includes a paddle, a gripping member, and an indicator. The paddle and/or the gripping member are movable to form an opening or capture region between the gripping member and the paddle. The indicator is configured to indicate whether a leaflet of the native valve is inserted into the opening or capture region between the paddle and the gripping member to at least a minimum insertion depth.

Abstract: The invention provides a transgenic corn event MON 95379, plants, plant cells, seeds, plant parts, progeny plants, and commodity products comprising event MON 95379. The invention also provides polynucleotides specific for event MON 95379 and methods for using and detecting event MON 95379 as well as plants, plant cells, seeds, plant pails, progeny plants, and commodity products comprising event MON 95379.

Abstract: The disclosed simulation environment, methods, and system support simultaneous design and analysis of assemblies with unified computer aided design (CAD) and finite element analysis (FEA). The system provides a simulation environment that is unified with the architecture of the assembly environment, which significantly reduces the amount of time it takes to set up structural simulations as compared to prior simulation tools. The system enables CAD designers to obtain accurate mechanical guidance such as strength and rigidity early and often in the design process, seeing the structural impact of CAD modifications at the sketch, part, and configuration level. Such guidance can be particularly helpful when CAD engineers are determining product fit and form, defining dimensions, and shaping the overall weight and volume of designs.

Abstract: A device includes a match element that includes a first data input configured to receive a first result, wherein the first result is of an analysis performed on at least a portion of a data stream by an element of a state machine. The match element also includes a second data input configured to receive a second result, wherein the second result is of an analysis performed on at least a portion of the data stream by another element of the state machine. The match element further includes an output configured to selectively provide the first result or the second result.

Abstract: A chemical mechanical polishing apparatus has a platen to support a polishing pad, a carrier head comprising a rigid housing and configured to hold a surface of a substrate against the polishing pad, a motor to generate relative motion between the platen and the carrier head so as to polish the substrate, an in-situ carrier head monitoring system including a sensor positioned to interact with the housing and to detect vibrational motion of the housing and generate signals based on the detected vibrational motion, and a controller. The controller is configured to generate a value for a carrier head status parameter based on received signals from the in-situ carrier head monitoring system, and change a polishing parameter or generate an alert based on the carrier head status parameter.

Abstract: Energy consumption may be reduced by tracking a measure of baseline energy over time in order to determine which of the one or more appliances have a power on mode and a power standby mode based at least in part on the measure of baseline energy delivered to each of the appliances during the baseline time period, wherein the power standby mode consumes less power than the power on mode. During subsequent operation, the supervisor identifies when an appliance is in a power standby mode, and turns off the socket receptacles of the smart sockets that corresponds to those appliances identified as being in their power standby mode.

Abstract: For each discovered smart socket, the smart socket is automatically added to a supervisor database and a predetermined set of two or more objects for the smart socket are automatically added to the supervisor database. One or more predetermined alarm extensions are automatically added to predetermined ones of the two or more objects of the smart socket in the supervisor database. One or more predetermined history extensions are automatically added to predetermined ones of the two or more objects of the smart socket in the supervisor database. Predetermined ones of the two or more objects and/or extensions of each of the discovered smart sockets are automatically mapped to a predetermined dashboard.

Abstract: A method for maintaining a measure of accumulated energy delivered to an appliance includes a supervisor repeatedly receiving from a first smart socket a measure of energy delivered to the appliance by the first smart socket and maintaining a measure of accumulated energy delivered to the appliance. When the first smart socket fails and is replaced, the method includes repeatedly receiving from the second smart socket a measure of energy delivered to the appliance by the second smart socket, maintaining the measure of accumulated energy delivered to the appliance based at least in part on the measures previously received from the first smart socket and the measures repeatedly received from the second smart socket of energy delivered to the appliance by the second smart socket, and displaying the measure of accumulated energy delivered to the appliance on a dashboard.

Abstract: Table top sanitizer dispenser bottle bases are disclosed herein. An exemplary table top sanitizer dispenser bottle base includes a movable upper housing, the upper moveable housing has a floor with an aperture located therein and a peripheral wall. The top sanitizer dispenser bottle includes a lower stationary housing. The upper movable housing is connected to the lower stationary housing and is configured to move linearly upward and downward with respect to lower stationary. One or more biasing members bias the upper movable housing upward. A switch is included and the upper movable housing has an engagement member or surface for actuating the switch upon downward movement of the upper movable housing. At least one of a visual indicator and an audible indicator are also included. Control circuitry is provided for activating the one or more of a visual indicator and audible indicator when the engagement member actuates the switch.