Abstract: The present invention relates to an implant having a surface comprising a coating on at least a portion of the surface of the implant, wherein the coating comprises at least two coating layers of bioactive compounds adjacent to each other, obtainable in a process comprising the following steps: providing an implant with a surface, providing a first suspension comprising at least one first bioactive compound in a first solvent, wherein the first bioactive compound is non-soluble or partially soluble in the first solvent, applying said first suspension comprising the at least one first bioactive compound onto at least a part of the implant surface forming a first coating layer; drying the first coating layer, providing a second solution comprising at least one second bioactive compound in a second solvent, wherein the second bioactive compound is soluble or readily soluble in the second solvent; applying said second solution comprising the at least one second bioactive compound onto the first coating layer form

Abstract: The present invention relates to an implant having a surface comprising a coating on at least a portion of the surface of the implant, wherein the coating comprises at least two coating layers of bioactive compounds adjacent to each other, obtainable in a process comprising the following steps: providing an implant with a surface, providing a first suspension comprising at least one first bioactive compound in a first solvent, wherein the first bioactive compound is non-soluble or partially soluble in the first solvent, applying said first suspension comprising the at least one first bioactive compound onto at least a part of the implant surface forming a first coating layer; drying the first coating layer, providing a second solution comprising at least one second bioactive compound in a second solvent, wherein the second bioactive compound is soluble or readily soluble in the second solvent; applying said second solution comprising the at least one second bioactive compound onto the first coating layer form

Abstract: A device (100) for determining the solution rate and release kinetics of aerosol formulations comprises an inhaler (2) connected to a cascade impactor (3), wherein a membrane (6) is disposed on a filter plate of the cascade impactor (2), and an air-liquid model system with a device for collecting measured data.

Abstract: The present invention pertains to a three compartment structured polymer nanoparticle (core-shell-corona) for multimodal imaging with specificity for cells or cellular components, thus enabling more advanced diagnostic approaches and targeted therapy on the cellular level without the use of additional biologically active materials.

Abstract: A device (100) for determining the solution rate and release kinetics of aerosol formulations comprises an inhaler (2) connected to a cascade impactor (3), wherein a membrane (6) is disposed on a filter plate of the cascade impactor (2), and an air-liquid model system with a device for collecting measured data.

Abstract: The invention relates to the preparation of inhalable powders which exhibit a delayed release of active substance and processes for preparing them as well as medicaments that can be produced using these inhalable powders.

Abstract: The invention relates to the preparation of stable, polymer-based emulsions which have an ionic strength of more than 10 mM in their aqueous phase, and to processes for preparing them and medicaments that can be obtained using these emulsions.

Abstract: The present invention pertains to a three compartment structured polymer nanoparticle (core-shell-corona) for multimodal imaging with specificity for cells or cellular components, thus enabling more advanced diagnostic approaches and targeted therapy on the cellular level without the use of additional biologically active materials.

Abstract: The invention relates to a method for improving transfection efficiency through the use of K16-peptides. In addition, the invention further relates to novel K16-peptides, including a K16-CYC peptide.

Abstract: The invention relates to a method for improving transfection efficiency by using K16 peptides. The invention further relates to novel K16 peptides, especially to the K16-CYCi, having the peptide sequence: K1 CYC (1). and to K16mVprN having the peptde sequence KKKKKKKKKKKKKKKGGGC NEWTLELLEELKNEAVRHE.