Patents by Inventor R. Michael Roe
R. Michael Roe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20130005573Abstract: Compositions and methods of use for ketones and aldehydes as herbicides are disclosed herein. According to an aspect, a method includes applying an effective amount of an herbicide composition comprising an acyclic, chemically-synthesized or plant-derived ketone or aldehyde of the invention to a locus where undesirable vegetation is to be controlled. The plant-derived or synthesized ketone may be a 2-undecanone. Further, various other acyclic ketones and aldehydes and their derivatives may be used.Type: ApplicationFiled: March 3, 2011Publication date: January 3, 2013Applicant: North Carolina State UniversityInventors: R. Michael Roe, George Kennedy
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Publication number: 20110189251Abstract: A method of killing a pest such as an arthropod or invertebrate pest comprises contacting an active agent such as 2-undecanone to said pest in an amount effective to kill said pest. In some embodiments, the contacting step is carried out by applying the active agent such as 2-undecanone or composition containing the same to a plant or animal (e.g., a human, or other mammalian species such as dog, cat, horse, pig, cow sheep, goat, etc.) in an amount substantially non-toxic to said plant or animal. In some embodiments, the contacting step is carried out by applying said active agent such as 2-undecanone as a composition (e.g., an aqueous composition) comprising said 2-undecanone in combination with a soy methyl ester. The composition may be in the form of an emulsion (including microemulsions).Type: ApplicationFiled: June 24, 2008Publication date: August 4, 2011Inventors: R. Michael Roe, Allen L. Jones, JR.
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Patent number: 7455975Abstract: An electrochemical detection system which specifically detects selected nucleic acid segments is described. The system utilizes biological probes such as nucleic acid or peptide nucleic acid probes which are complementary to and specifically hybridize with selected nucleic acid segments in order to generate a measurable current when an amperometric potential is applied. The electrochemical signal can be quantified.Type: GrantFiled: January 3, 2007Date of Patent: November 25, 2008Assignee: ESA Biosciences, Inc.Inventors: Robert W. Henkens, John P. O'Daly, Marek Wojciechowski, Honghua Zhang, Najih Naser, R. Michael Roe, Thomas N. Stewart, Deborah M. Thompson, Rebecca Sundseth, Steven E. Wegner
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Patent number: 7288573Abstract: A method of repelling an insect pest such as a tick, mosquito or cockroach comprises applying to a subject or substrate, in an amount effect to repel the insect pest, a compound of Formula I: wherein R is C4-C20 linear or branched alkyl. Particularly preferred compounds of Formula (I) are 2-tridecanone and 2-undecanone.Type: GrantFiled: February 14, 2002Date of Patent: October 30, 2007Assignee: North Carolina State UniversityInventor: R. Michael Roe
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Patent number: 7169358Abstract: An electrochemical detection system which specifically detects selected nucleic acid segments is described. The system utilizes biological probes such as nucleic acid or peptide nucleic acid probes which are complementary to and specifically hybridize with selected nucleic acid segments in order to generate a measurable current when an amperometric potential is applied. The electrochemical signal can be quantified.Type: GrantFiled: February 25, 2002Date of Patent: January 30, 2007Inventors: Robert W. Henkens, John P. O'Daly, Marek Wojciechowski, Honghua Zhang, Najih Naser, R. Michael Roe, Thomas N. Stewart, Deborah M. Thompson, Rebecca Sundseth, Steven E. Wegner
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Publication number: 20040242703Abstract: A method of repelling an insect pest such as a tick, mosquito or cockroach comprises applying to a subject or substrate, in an amount effect to repel the insect pest, a compound of Formula I: 1Type: ApplicationFiled: July 23, 2004Publication date: December 2, 2004Inventor: R. Michael Roe
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Patent number: 6800662Abstract: A method of repelling an insect pest such as a tick, mosquito or cockroach comprises applying to a subject or substrate, in an amount effect to repel the insect pest, a compound of Formula I: wherein R is C4-C20 linear or branched alkyl. Particularly preferred compounds of Formula (I) are 2-tridecanone and 2-undecanone.Type: GrantFiled: June 21, 2002Date of Patent: October 5, 2004Assignee: North Carolina State UniversityInventor: R. Michael Roe
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Publication number: 20040072158Abstract: An electrochemical detection system which specifically detects selected nucleic acid segments is described. The system utilizes biological probes such as nucleic acid or peptide nucleic acid probes which are complementary to and specifically hybridize with selected nucleic acid segments in order to generate a measurable current when an amperometric potential is applied. The electrochemical signal can be quantified.Type: ApplicationFiled: February 25, 2002Publication date: April 15, 2004Inventors: Robert W. Henkens, John P. O'Daly, Marek Wojciechowski, Honghua Zhang, Najih Naser, R. Michael Roe, Thomas N. Stewart, Deborah M. Thompson, Rebecca Sundseth, Steven E. Wegner
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Publication number: 20040034097Abstract: The present invention provides non-peptide organic compounds that have a structure analogous to or reminiscent of the TMOF structure and have pesticidal activity. Thus the present invention concerns pesticidal compounds that inhibit digestion in pests by terminating or otherwise blocking synthesis of digestive enzymes by activating a TMOF receptor (collectively referred to herein as “pesticidal compounds”). The pesticidal compounds and other compounds of the present invention are usefully employed in the control of pests, particularly insect pests Such as mosquitoes, which ingest blood.Type: ApplicationFiled: August 13, 2003Publication date: February 19, 2004Inventors: Russell J. Linderman, R. Michael Roe, Deborah M. Thompson, Matthew Vanderherehen
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Patent number: 6660770Abstract: The present invention provides non-peptide organic compounds that have a structure analogous to or reminiscent of the TMOF structure and have pesticidal activity. Thus the present invention concerns pesticidal compounds that inhibit digestion in pests by terminating or otherwise blocking synthesis of digestive enzymes by activating a TMOF receptor (collectively referred to herein as “pesticidal compounds”). The pesticidal compounds and other compounds of the present invention are usefully employed in the control of pests, particularly insect pests such as mosquitoes, which ingest blood.Type: GrantFiled: June 7, 2001Date of Patent: December 9, 2003Assignee: North Carolina State UniversityInventors: Russell J. Linderman, R. Michael Roe, Deborah M. Thompson, Matthew Vanderherehen
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Publication number: 20030108585Abstract: Insecticidal compounds comprising an insecticidal peptide (e.g., juvenile hormone esters) or nucleic acid (e.g. Ea baculovirus) or insecticide covalently conjugated to a polymer are described. Methods of use thereof for controlling insects and compositions containing the same are also described.Type: ApplicationFiled: October 31, 2002Publication date: June 12, 2003Inventors: R. Michael Roe, Alan E. Brandt
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Publication number: 20030083387Abstract: A method of repelling an insect pest such as a tick, mosquito or cockroach comprises applying to a subject or substrate, in an amount effect to repel the insect pest, a compound of Formula I: 1Type: ApplicationFiled: June 21, 2002Publication date: May 1, 2003Inventor: R. Michael Roe
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Patent number: 6517856Abstract: Methods of assaying insects for pesticide resistance and to identify insect species are based on feeding disruption caused by insecticide such as the biopesticide Bacillius thuringiensis toxin (Bt). Further provided are methods for monitoring insecticide resistance in a population of insects, as well as methods of screening compounds for insecticidal activity. Insecticide resistance can be assessed at the level of an individual insect or at population levels. Apparatus and dehydrated insect meal pads useful in such assays are described.Type: GrantFiled: May 9, 2000Date of Patent: February 11, 2003Assignees: Agdia Incorporated, North Carolina State UniversityInventors: R. Michael Roe, Woodward D. Bailey, Fred Gould, George G. Kennedy, Chester L. Sutula
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Publication number: 20020193436Abstract: The present invention provides non-peptide organic compounds that have a structure analogous to or reminiscent of the TMOF structure and have pesticidal activity. Thus the present invention concerns pesticidal compounds that inhibit digestion in pests by terminating or otherwise blocking synthesis of digestive enzymes by activating a TMOF receptor (collectively referred to herein as “pesticidal compounds”). The pesticidal compounds and other compounds of the present invention are usefully employed in the control of pests, particularly insect pests such as mosquitoes, which ingest blood.Type: ApplicationFiled: June 7, 2001Publication date: December 19, 2002Inventors: Russell J. Linderman, R. Michael Roe, Deborah M. Thompson, Matthew Vanderherehen
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Publication number: 20020187178Abstract: Insecticidal compounds comprising an insecticidal peptide (e.g., Juvenile hormone esterase) or nucleic acid (e.g. a baculovirus) covalently conjugated to a water soluble polymer such as polyethylene glycol are described. Methods of use thereof for controlling insects such as moths, and compositions containing the same are also described.Type: ApplicationFiled: May 3, 2002Publication date: December 12, 2002Inventor: R. Michael Roe
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Patent number: 6437001Abstract: A method of repelling an insect pest such as a tick, mosquito or cockroach comprises applying to a subject or substrate, in an amount effect to repel the insect pest, a compound of Formula I: wherein R is C4-C20 linear or branched alkyl. Particularly preferred compounds of Formula (I) are 2-tridecanone and 2-undecanone.Type: GrantFiled: March 14, 2001Date of Patent: August 20, 2002Assignee: North Carolina State UniversityInventor: R. Michael Roe
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Patent number: 6391558Abstract: An electrochemical detection system which specifically detects selected nucleic acid segments is described. The system utilizes biological probes such as nucleic acid or peptide nucleic acid probes which are complementary to and specifically hybridize with selected nucleic acid segments in order to generate a measurable current when an amperometric potential is applied. The electrochemical signal can be quantified.Type: GrantFiled: April 14, 2000Date of Patent: May 21, 2002Assignee: Andcare, Inc.Inventors: Robert W. Henkens, John P. O'Daly, Marek Wojciechowski, Honghua Zhang, Najih Naser, R. Michael Roe, Thomas N. Stewart, Deborah M. Thompson, Rebecca Sundseth, Steven E. Wegner
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Patent number: 6060039Abstract: Methods of assaying insects for pesticide resistance and to identify insect species are based on feeding disruption caused by pesticides such as the biopesticide Bacillus thuringiensis toxin (Bt). The assay end-point is feeding disruption, measured by the fecal production of insects exposed to a diagnostic dose of pesticide in a test diet. Pesticide resistance can be assessed at the level of an individual insect or at population levels. Apparatus useful in such assays are described.Type: GrantFiled: July 8, 1998Date of Patent: May 9, 2000Assignee: North Carolina State UniversityInventors: R. Michael Roe, Woodward D. Bailey, Fred Gould, George G. Kennedy