Patents by Inventor R. Pease

R. Pease has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230419593
    Abstract: Various implementations disclosed herein include devices, systems, and methods that present views of media objects using different viewing states determined based on context. In some implementations, a view of a 3D environment is presented. Then, a context associated with viewing one or more media objects within the 3D environment is determined, the media objects associated with data for providing an appearance of depth within the one or more media objects. Based on the context, a viewing state is determined for viewing a media object of the one or more media objects within the 3D environment, the viewing state defining whether the media object will be presented as a planar object or with depth within the media object. In accordance with a determination that the viewing state is a first viewing state, the media object is presented within the 3D environment using its associated data for providing the appearance of depth.
    Type: Application
    Filed: September 11, 2023
    Publication date: December 28, 2023
    Inventors: Alexandre Da Veiga, Tobias Rick, Timothy R. Pease
  • Publication number: 20230298281
    Abstract: In an exemplary process, a set of parameters corresponding to characteristics of a physical setting of a user is obtained. Based on the parameters, at least one display placement value and a fixed boundary location corresponding to the physical setting are obtained. In accordance with a determination that the at least one display placement value satisfies a display placement criterion, a virtual display is displayed at the fixed boundary location corresponding to the physical setting.
    Type: Application
    Filed: December 20, 2022
    Publication date: September 21, 2023
    Inventors: Timothy R. PEASE, Alexandre DA VEIGA, David H. Y. HUANG, Peng LIU, Robert K. MOLHOLM
  • Patent number: 11763477
    Abstract: Various implementations disclosed herein include devices, systems, and methods that determines a distance between a portion (e.g., top) of a person's head and the floor below as an estimate of the person's height. For example, an example process may include determining a first position on a head of a person in a three-dimensional (3D) coordinate system, the first position determined based on detecting a feature on the head based on a two-dimensional (2D) image of the person in a physical environment, determining a second position on a floor below the first position in the 3D coordinate system, and estimating a height based on determining a distance between the first position and the second position.
    Type: Grant
    Filed: February 23, 2021
    Date of Patent: September 19, 2023
    Assignee: Apple Inc.
    Inventors: Alexandre Da Veiga, George J. Hito, Timothy R. Pease
  • Publication number: 20230281933
    Abstract: Various implementations disclosed herein include devices, systems, and methods that create a 3D video that includes determining first adjustments (e.g., first transforms) to video frames (e.g., one or more RGB images and depth images per frame) to align content in a coordinate system to remove the effects of capturing camera motion. Various implementations disclosed herein include devices, systems, and methods that playback a 3D video and includes determining second adjustments (e.g., second transforms) to remove the effects of movement of a viewing electronic device relative to a viewing environment during playback of the 3D video. Some implementations distinguish static content and moving content of the video frames to playback only moving objects or facilitate concurrent playback of multiple spatially related 3D videos. The 3D video may include images, audio, or 3D video of a video-capture-device user.
    Type: Application
    Filed: November 10, 2022
    Publication date: September 7, 2023
    Inventors: Timothy R. PEASE, Alexandre DA VEIGA, Benjamin H. BOESEL, David H. HUANG, Jonathan PERRON, Shih-Sang CHIU, Spencer H. RAY
  • Publication number: 20220251157
    Abstract: Materials and methods for using multivalent molecules (e.g., antibodies) to modulate cellular function. A molecule can be targeted to a particular type of cell, either through direct binding to an epitope on the surface of the cell, or through a linker that recognizes both the multivalent molecule and a marker on the cell surface.
    Type: Application
    Filed: February 17, 2022
    Publication date: August 11, 2022
    Inventors: Larry R. PEASE, Moses RODRIGUEZ
  • Patent number: 11274131
    Abstract: Materials and methods for using multivalent molecules (e.g., antibodies) to modulate cellular function. A molecule can be targeted to a particular type of cell, either through direct binding to an epitope on the surface of the cell, or through a linker that recognizes both the multivalent molecule and a marker on the cell surface.
    Type: Grant
    Filed: December 27, 2018
    Date of Patent: March 15, 2022
    Assignee: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Larry R. Pease, Moses Rodriguez
  • Publication number: 20210295548
    Abstract: Various implementations disclosed herein include devices, systems, and methods that determines a distance between a portion (e.g., top) of a person's head and the floor below as an estimate of the person's height. For example, an example process may include determining a first position on a head of a person in a three-dimensional (3D) coordinate system, the first position determined based on detecting a feature on the head based on a two-dimensional (2D) image of the person in a physical environment, determining a second position on a floor below the first position in the 3D coordinate system, and estimating a height based on determining a distance between the first position and the second position.
    Type: Application
    Filed: February 23, 2021
    Publication date: September 23, 2021
    Inventors: Alexandre Da Veiga, George J. Hito, Timothy R. Pease
  • Publication number: 20200397877
    Abstract: Materials and methods for identifying and using MEW molecule variants for activating self-reactive T cells in a peptide-specific manner, and their use to focus autoimmune cellular responses against diseases such as cancers and persisting viral infections, are described.
    Type: Application
    Filed: September 1, 2020
    Publication date: December 24, 2020
    Inventor: Larry R. Pease
  • Publication number: 20200397898
    Abstract: Specific binding members, particularly human antibodies, particularly recombinant antibodies, and fragments thereof, which are capable of binding to and recognizing neurons in the CNS and eliciting responses in CNS neurons are provided. The antibodies are useful for neuroprotection and in the diagnosis and treatment of conditions associated with nerve damage, injury or degeneration and neurodegenerative disease. The antibodies, variable regions or CDR domain sequences thereof, and fragments thereof of the invention may also be used in therapy in combination with chemotherapeutics, immune modulators, or neuroactive agents and/or with other antibodies or fragments thereof. Antibodies are exemplified by the antibodies IgM12 and IgM42 whose sequences are provided herein.
    Type: Application
    Filed: May 7, 2020
    Publication date: December 24, 2020
    Inventors: Moses Rodriguez, Arthur E. Warrington, Larry R. Pease
  • Patent number: 10792348
    Abstract: Materials and methods for identifying and using MEW molecule variants for activating self-reactive T cells in a peptide-specific manner, and their use to focus autoimmune cellular responses against diseases such as cancers and persisting viral infections, are described.
    Type: Grant
    Filed: April 22, 2016
    Date of Patent: October 6, 2020
    Assignee: Mayo Foundation for Medical Education and Research
    Inventor: Larry R. Pease
  • Publication number: 20200171170
    Abstract: This document relates to materials and methods for activating naïve T cells in vivo. For example, methods of activating naïve T cells in vivo to treat cancer are provided.
    Type: Application
    Filed: June 15, 2018
    Publication date: June 4, 2020
    Applicant: Mayo Foundation for Medical Education and Research
    Inventor: Larry R. Pease
  • Publication number: 20200017587
    Abstract: An antibody capable of potentiating immune responses and modifying existing states of immune responsiveness is described, as is the sequence of the antibody. Also described are compositions containing the antibody, as well as methods for using the antibody and the compositions to enhance immune responses, to enhance DC function, to modify an existing state of immune responsiveness, to immunize individuals, or to treat or inhibit conditions such as allergic asthma.
    Type: Application
    Filed: February 28, 2019
    Publication date: January 16, 2020
    Applicant: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Larry R. Pease, Virginia Van Keulen, Bogolub Ciric
  • Publication number: 20190256568
    Abstract: Materials and methods for using multivalent molecules (e.g., antibodies) to modulate cellular function. A molecule can be targeted to a particular type of cell, either through direct binding to an epitope on the surface of the cell, or through a linker that recognizes both the multivalent molecule and a marker on the cell surface.
    Type: Application
    Filed: December 27, 2018
    Publication date: August 22, 2019
    Inventors: Larry R. Pease, Moses Rodriguez
  • Patent number: 10369513
    Abstract: Ancillary embodiments and modifications to a homogenizer unit (“PPH”), and methods of use directed to purification of biogas or other raw methane streams. The apparatus includes a homogenizer body, one or more stream inlets (for the raw methane), one or more chilled water inlets, a mixing zone where the water stream is commingled with the raw methane stream, and a venturi immediately downstream from the mixing zone such that the commingled streams are pulled into the venturi resulting in homogenization. The PPH components are insulated to maintain the chilled water of the various streams at a cooled, below ambient temperature, increasing dissolution of the contaminant gases into the chilled water, and producing a purified methane stream including little or no H2S and CO2.
    Type: Grant
    Filed: September 6, 2017
    Date of Patent: August 6, 2019
    Inventors: John R. Pease, John F. Blatnick
  • Patent number: 10351620
    Abstract: Antibodies, particularly human antibodies, are disclosed having activity in treatment of demyelinating diseases and diseases of the central nervous system. Neuromodulatory agents are provided comprising a material selected from the group consisting of an antibody capable of binding structures or cells in the central nervous system, a peptide analog, and active fragments, monomers and combinations thereof having one or more of the following characteristics: capable of inducing remyelination; binding to neural tissue; promoting Ca++ signaling with oligodendrocytes; and promoting cellular proliferation of glial cells. Amino acid and DNA sequences of exemplary antibodies are disclosed. Methods are described for treating demyelinating diseases, and diseases of the central nervous system, using polyclonal IgM antibodies and human monoclonal antibodies sHIgm22(LYM 22), sHIgm46(LYM46) ebvHIgM MSI19D10, CB2bG8, AKJR4, CB2iE12, CB2iE7, MSI19E5 and MSI10E10, and active fragments thereof.
    Type: Grant
    Filed: June 21, 2017
    Date of Patent: July 16, 2019
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Moses Rodriguez, David J. Miller, Larry R. Pease
  • Patent number: 10253097
    Abstract: An antibody capable of potentiating immune responses and modifying existing states of immune responsiveness is described, as is the sequence of the antibody. Also described are compositions containing the antibody, as well as methods for using the antibody and the compositions to enhance immune responses, to enhance DC function, to modify an existing state of immune responsiveness, to immunize individuals, or to treat or inhibit conditions such as allergic asthma.
    Type: Grant
    Filed: January 6, 2016
    Date of Patent: April 9, 2019
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Larry R. Pease, Virginia Van Keulen, Bogolub Ciric
  • Patent number: 10202430
    Abstract: Materials and methods for using multivalent molecules (e.g., antibodies) to modulate cellular function. A molecule can be targeted to a particular type of cell, either through direct binding to an epitope on the surface of the cell, or through a linker that recognizes both the multivalent molecule and a marker on the cell surface. The invention provides a chimeric polypeptide comprising a first amino acid sequence and a second amino acid sequence, wherein the first amino acid sequence comprises an WIC Class I peptide sequence, and where the second amino acid sequence comprises an epitope to which a multivalent molecule binds, including wherein the multivalent molecule is an IgM antibody, including antibody hIgM22. The invention provides a linker molecule for targeting IgM antibody, including antibody hIgM22, to a cell in the oligodendrocyte lineage.
    Type: Grant
    Filed: October 17, 2008
    Date of Patent: February 12, 2019
    Assignee: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Larry R. Pease, Moses Rodriguez
  • Publication number: 20180193863
    Abstract: The present disclosure sets forth an automated apparatus and method for applying gas plasma coatings to aircraft engine parts. The process and apparatus employ a plurality of sensors which continually monitor various process parameters associated with the coating process. If any of the measured parameters fall out of tolerance, the coating process is interrupted to allow a user to fix the source of the problem, where upon the process is reengaged. Moreover, the process and apparatus employ a pause resume circuit which uses predetermined durations for pausing and resuming the coating process.
    Type: Application
    Filed: March 6, 2018
    Publication date: July 12, 2018
    Inventor: John R. Pease
  • Patent number: 9937512
    Abstract: The present disclosure sets forth an automated apparatus and method for applying gas plasma coatings to aircraft engine parts. The process and apparatus employ a plurality of sensors which continually monitor various process parameters associated with the coating process. If any of the measured parameters fall out of tolerance, the coating process is interrupted to allow a user to fix the source of the problem, where upon the process is reengaged. Moreover, the process and apparatus employ a pause resume circuit which uses predetermined durations for pausing and resuming the coating process.
    Type: Grant
    Filed: February 7, 2012
    Date of Patent: April 10, 2018
    Assignee: UNITED TECHNOLOGIES CORPORATION
    Inventor: John R. Pease
  • Publication number: 20180086821
    Abstract: Antibodies, particularly human antibodies, are disclosed having activity in treatment of demyelinating diseases and diseases of the central nervous system. Neuromodulatory agents are provided comprising a material selected from the group consisting of an antibody capable of binding structures or cells in the central nervous system, a peptide analog, and active fragments, monomers and combinations thereof having one or more of the following characteristics: capable of inducing remyelination; binding to neural tissue; promoting Ca++ signaling with oligodendrocytes; and promoting cellular proliferation of glial cells. Amino acid and DNA sequences of exemplary antibodies are disclosed. Methods are described for treating demyelinating diseases, and diseases of the central nervous system, using polyclonal IgM antibodies and human monoclonal antibodies sHIgm22(LYM 22), sHIgm46(LYM46) ebvHIgM MSI19D10, CB2bG8, AKJR4, CB2iE12, CB2iE7, MSI19E5 and MSI10E10, and active fragments thereof.
    Type: Application
    Filed: June 21, 2017
    Publication date: March 29, 2018
    Inventors: Moses Rodriguez, David J. Miller, Larry R. Pease