Patents by Inventor Rachel Macmaster

Rachel Macmaster has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for increasing the efficiency of double-strand-break induced mutagenesis
    Patent number: 9540623
    Abstract: The present invention relates to a method for increasing double-strand-break induced mutagenesis at a genomic locus of interest in a cell, thereby giving new tools for genome engineering, including therapeutic applications and cell line engineering. More specifically, the present invention concerns the combined use of TALEN or meganucleases with TREX2, especially under the form of single-chain proteins.
    Type: Grant
    Filed: July 3, 2012
    Date of Patent: January 10, 2017
    Assignee: CELLECTIS
    Inventors: George H. Silva, Rachel Macmaster
  • METHOD FOR INCREASING THE EFFICIENCY OF DOUBLE-STRAND-BREAK INDUCED MUTAGENESIS
    Publication number: 20140234975
    Abstract: The present invention relates to a method for increasing double-strand-break induced mutagenesis at a genomic locus of interest in a cell, thereby giving new tools for genome engineering, including therapeutic applications and cell line engineering. More specifically, the present invention concerns the combined use of TALEN or meganucleases with TREX2, especially under the form of single-chain proteins.
    Type: Application
    Filed: July 3, 2012
    Publication date: August 21, 2014
    Applicant: CELLECTIS
    Inventors: George H Silva, Rachel Macmaster