Patents by Inventor Rachel Ofir

Rachel Ofir has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR TREATING VIRAL INFECTIONS AND SEQUELAE THEREOF
    Publication number: 20230338432
    Abstract: Disclosed herein are methods and compositions comprising placental adherent stromal cells for treating viral infections and sequelae thereof.
    Type: Application
    Filed: March 11, 2021
    Publication date: October 26, 2023
    Applicant: PLURISTEM LTD.
    Inventors: Yaacob YANAY, Rachel OFIR, Marc TRITEL
  • METHODS AND COMPOSITIONS FOR ENRICHMENT OF TARGET CELLS
    Publication number: 20230190822
    Abstract: Disclosed herein are compositions comprising subcellular fractions from expanded placental adherent stromal cells, and methods utilizing same.
    Type: Application
    Filed: May 5, 2021
    Publication date: June 22, 2023
    Inventors: Rachel Ofir, Zami Aberman, Niva Shraga Heled
  • ADHERENT CELLS FROM ADIPOSE OR PLACENTA TISSUES AND USE THEREOF IN THERAPY
    Publication number: 20220378847
    Abstract: A method of treating ischemia in a subject in need thereof is disclosed. The method comprising administering to the subject a therapeutically effective amount of adherent cells of a tissue selected from the group consisting of a placenta and an adipose tissue, thereby treating the ischemia in the subject. A method of treating a medical condition requiring connective tissue regeneration and/or repair is also disclosed.
    Type: Application
    Filed: August 4, 2022
    Publication date: December 1, 2022
    Inventors: Moran Meiron, Amir Toren, Rachel Ofir, Zami Aberman, Nirit Drori-Carmi
  • METHODS AND COMPOSITIONS FOR TREATING SUBJECTS EXPOSED TO VESICANTS AND OTHER CHEMICAL AGENTS
    Publication number: 20210353687
    Abstract: Disclosed herein are methods and compositions comprising adherent stromal cells.
    Type: Application
    Filed: June 18, 2019
    Publication date: November 18, 2021
    Applicant: PLURISTEM LTD.
    Inventors: Arie EISENKRAFT, Yaacob YANAY, Rachel OFIR
  • THERAPEUTIC METHODS AND COMPOSITIONS
    Publication number: 20210338740
    Abstract: Disclosed herein are pharmaceutical compositions and methods comprising or utilizing placental adherent stromal cells. The pharmaceutical compositions may be indicated for ameliorating or treating various disorders, e.g., impaired glucose tolerance. Alternatively, the pharmaceutical composition may be indicated for ameliorating or treating systemic inflammation, e.g., in a subject with impaired glucose tolerance. The pharmaceutical compositions may further include pharmacologically acceptable excipients.
    Type: Application
    Filed: November 6, 2019
    Publication date: November 4, 2021
    Applicant: PLURISTEM LTD.
    Inventors: Zami ABERMAN, Yaacob YANAY, Rachel OFIR, Marc TRITEL, Hoshea Yissachar ALLEN, Niva SHRAGA HELED
  • METHODS AND COMPOSITIONS FOR TREATING VIRAL INFECTIONS
    Publication number: 20210283189
    Abstract: Disclosed herein are methods and compositions comprising placental adherent stromal cells for treating viral infections and sequelae thereof.
    Type: Application
    Filed: March 11, 2021
    Publication date: September 16, 2021
    Applicant: PLURISTEM LTD.
    Inventors: Yaacob Yanay, Rachel Ofir, Marc Tritel
  • THERAPEUTIC DOSAGE REGIMENS COMPRISING ADHERENT STROMAL CELLS
    Publication number: 20210228635
    Abstract: Disclosed herein are pharmaceutical compositions and therapeutic dosage regimens comprising or utilizing adherent stromal cells. The adherent stromal cells may be derived e.g. from placental tissue, from adipose tissue, or from bone marrow. The pharmaceutical compositions may be indicated for treating various disorders, e.g. ischemic disorders, hematopoietic disorders, and neurodegenerative disorders, inflammatory disorders, and neoplasms. The pharmaceutical compositions may further include pharmacologically acceptable excipients.
    Type: Application
    Filed: June 10, 2019
    Publication date: July 29, 2021
    Applicant: PLURISTEM LTD.
    Inventors: Zami ABERMAN, Yaacob YANAY, Rachel OFIR, Marc TRITEL
  • METHODS AND COMPOSITIONS FOR TREATING CANCERS AND NEOPLASMS
    Publication number: 20210205370
    Abstract: Described herein are methods of anti-tumor therapy using adherent stromal cells and conditioned medium produced thereby.
    Type: Application
    Filed: February 16, 2017
    Publication date: July 8, 2021
    Inventors: Zami Aberman, Rachel Ofir, Hoshea Yissachar Allen, Ariel Gilert, Niva Shraga Heled
  • METHODS AND COMPOSITIONS FOR TREATING NEUROLOGICAL DISORDERS
    Publication number: 20200246386
    Abstract: Disclosed herein are methods and compositions for cell induction and treating neurological disorders, utilizing adherent stromal cells, which may, for example, be derived from placental tissue, bone marrow, or adipose tissue. Also provided are pharmaceutical compositions comprising the described cells, optionally in combination with pharmaceutically acceptable excipients.
    Type: Application
    Filed: April 23, 2018
    Publication date: August 6, 2020
    Applicant: PLURISTEM LTD.
    Inventors: Rachel OFIR, Niva SHRAGA HELED
  • METHODS AND COMPOSITIONS FOR TREATING ADDICTIONS
    Publication number: 20200155611
    Abstract: Disclosed herein are methods and compositions comprising adherent stromal cells.
    Type: Application
    Filed: July 23, 2018
    Publication date: May 21, 2020
    Applicants: PLURISTEM LTD., BAR ILAN UNIVERSITY
    Inventors: Gal YADID, Rachel OFIR, Niva SHRAGA HELED
  • METHODS AND COMPOSITIONS FOR TUMOR ASSESSMENT
    Publication number: 20200080147
    Abstract: Described herein are methods and articles of manufacture for determining the suitability of a tumor or neoplastic cell to treatment with adherent stromal cells or with conditioned medium derived therefrom.
    Type: Application
    Filed: February 18, 2018
    Publication date: March 12, 2020
    Applicant: PLURISTEM LTD.
    Inventors: Zami ABERMAN, Rachel OFIR, Hoshea Yissachar ALLEN
  • Gene and protein expression properties of adherent stromal cells cultured in 3D
    Patent number: 10351910
    Abstract: Adherent stromal cells cultured under three dimensional conditions are provided, characterized, and distinguished from adherent stromal cells cultured under two dimensional conditions.
    Type: Grant
    Filed: February 20, 2014
    Date of Patent: July 16, 2019
    Assignee: PLURISTEM LTD
    Inventors: Rachel Ofir, Eytan Abraham
  • Methods and compositions for treating and preventing muscle wasting disorders
    Patent number: 10258652
    Abstract: Described herein are methods of treating and preventing muscle wasting and muscle loss, using adherent stromal cells and conditioned medium produced thereby.
    Type: Grant
    Filed: December 18, 2015
    Date of Patent: April 16, 2019
    Assignee: PLURISTEM LTD.
    Inventors: Esther Lukasiewicz Hagai, Rachel Ofir, Dana Fuchs Telem
  • ADHERENT CELLS FROM ADIPOSE OR PLACENTA TISSUES AND USE THEREOF IN THERAPY
    Publication number: 20180256648
    Abstract: A method of treating ischemia in a subject in need thereof is disclosed. The method comprising administering to the subject a therapeutically effective amount of adherent cells of a tissue selected from the group consisting of a placenta and an adipose tissue, thereby treating the ischemia in the subject. A method of treating a medical condition requiring connective tissue regeneration and/or repair is also disclosed.
    Type: Application
    Filed: August 5, 2013
    Publication date: September 13, 2018
    Applicant: Pluristem Ltd.
    Inventors: Moran Meiron, Amir Toren, Rachel Ofir, Zami Aberman, Nirit Drori-Carmi
  • METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING MUSCLE WASTING DISORDERS
    Publication number: 20170304370
    Abstract: Described herein are methods of treating and preventing muscle wasting and muscle loss, using adherent stromal cells and conditioned medium produced thereby.
    Type: Application
    Filed: December 18, 2015
    Publication date: October 26, 2017
    Inventors: Esther Lukasiewicz Hagai, Rachel Ofir, Dana Fuchs Telem
  • Adherent cells from adipose or placenta tissues and use thereof in therapy
    Patent number: 9517248
    Abstract: A method of treating ischemia in a subject in need thereof is disclosed. The method comprising administering to the subject a therapeutically effective amount of adherent cells of a tissue selected from the group consisting of a placenta and an adipose tissue, thereby treating the ischemia in the subject. A method of treating a medical condition requiring connective tissue regeneration and/or repair is also disclosed.
    Type: Grant
    Filed: February 13, 2014
    Date of Patent: December 13, 2016
    Assignee: Pluristem Ltd.
    Inventors: Moran Meiron, Amir Toren, Rachel Ofir, Zami Aberman, Nirit Drori-Carmi
  • GENE AND PROTEIN EXPRESSION PROPERTIES OF ADHERENT STROMAL CELLS CULTURED IN 3D
    Publication number: 20160186259
    Abstract: Adherent stromal cells cultured under three dimensional conditions are provided, characterized, and distinguished from adherent stromal cells cultured under two dimensional conditions.
    Type: Application
    Filed: February 20, 2014
    Publication date: June 30, 2016
    Applicant: Pluristem Ltd.
    Inventors: Rachel Ofir, Eytan Abraham
  • Adherent cells from placenta tissue and use thereof in therapy
    Patent number: 9096827
    Abstract: A method of culturing adherent cells from a placenta or adipose tissue is disclosed. The method comprising culturing the adherent cells from the placenta or adipose tissue under 2 dimensional (2D) culturing conditions which allow cell expansion, the conditions comprising continuous passaging of the cells for at least 4 passages.
    Type: Grant
    Filed: September 1, 2009
    Date of Patent: August 4, 2015
    Assignee: Pluristem Ltd.
    Inventors: Moran Meiron, Amir Toren, Rachel Ofir, Nirit Drori-Carmi
  • ADHERENT CELLS FROM ADIPOSE OR PLACENTA TISSUES AND USE THEREOF IN THERAPY
    Publication number: 20140242039
    Abstract: A method of treating ischemia in a subject in need thereof is disclosed. The method comprising administering to the subject a therapeutically effective amount of adherent cells of a tissue selected from the group consisting of a placenta and an adipose tissue, thereby treating the ischemia in the subject. A method of treating a medical condition requiring connective tissue regeneration and/or repair is also disclosed.
    Type: Application
    Filed: February 13, 2014
    Publication date: August 28, 2014
    Applicant: Pluristem Ltd.
    Inventors: Moran Meiron, Amir Toren, Rachel Ofir, Zami Aberman, Nirit Drori-Carmi
  • ADHERENT CELLS FROM PLACENTA TISSUE AND USE THEREOF IN THERAPY
    Publication number: 20130337558
    Abstract: A method of culturing adherent cells from a placenta or adipose tissue is disclosed. The method comprises culturing the adherent cells from the placenta or adipose tissue under 3 dimensional (3D) culturing conditions which allow cell expansion, the conditions comprising perfusion.
    Type: Application
    Filed: August 20, 2013
    Publication date: December 19, 2013
    Applicant: PLURISTEM LTD.
    Inventors: Moran Meiron, Amir Toren, Rachel Ofir, Nirit Drori-Carmi