Patents by Inventor Radhakrishnan P. Iyer

Radhakrishnan P. Iyer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE
    Publication number: 20240058461
    Abstract: Disclosed are compounds and compositions for the activation or induction of expression of a pattern recognition receptor (e.g., STING, RIG-I, MDA5), and methods of use thereof.
    Type: Application
    Filed: June 30, 2023
    Publication date: February 22, 2024
    Inventor: Radhakrishnan P. Iyer
  • Compounds,compositions, and methods for the treatment of disease
    Patent number: 11744845
    Abstract: Disclosed are compounds and compositions for the activation or induction of expression of a pattern recognition receptor (e.g., STING, RIG-I, MDA5), and methods of use thereof.
    Type: Grant
    Filed: June 4, 2021
    Date of Patent: September 5, 2023
    Assignee: F-star Therapeutics, Inc.
    Inventors: Radhakrishnan P. Iyer, Anjaneyulu Sheri, Seetharamaiyer Padmanabhan, Geeta Meher, Shenghua Zhou, Sreerupa Challa, Rayomand H. Gimi, Dillon Cleary
  • COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE
    Publication number: 20230271999
    Abstract: Disclosed are compounds and compositions for the activation or induction of expression of a pattern recognition receptor (e.g., STING, RIG-I, MDA5), and methods of use thereof.
    Type: Application
    Filed: January 20, 2023
    Publication date: August 31, 2023
    Inventors: Radhakrishnan P. Iyer, Geeta Meher, Anjaneyulu Sheri, Shenghua Zhou, Sreerupa Challa, Rayomand H. Gimi, Seetharamaiyer Padmanabhan, Dillon Cleary
  • Compounds, compositions, and methods for the treatment of disease
    Patent number: 11707531
    Abstract: Disclosed are compounds and compositions for the activation or induction of expression of a pattern recognition receptor (e.g., STING, RIG-I, MDA5), and methods of use thereof.
    Type: Grant
    Filed: September 11, 2018
    Date of Patent: July 25, 2023
    Assignee: F-star Therapeutics, Inc.
    Inventor: Radhakrishnan P. Iyer
  • Compounds, compositions, and methods for the treatment of disease
    Patent number: 11638716
    Abstract: Disclosed are compounds and compositions for the activation or induction of expression of a pattern recognition receptor (e.g., STING, RIG-I, MDA5), and methods of use thereof.
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: May 2, 2023
    Assignee: F-star Therapeutics, Inc.
    Inventors: Radhakrishnan P. Iyer, Anjaneyulu Sheri, Geeta Meher, Sreerupa Challa, Shenghua Zhou
  • Compounds, compositions, and methods for the treatment of disease
    Patent number: 11584774
    Abstract: Disclosed are compounds and compositions for the activation or induction of expression of a pattern recognition receptor (e.g., STING, RIG-I, MDA5), and methods of use thereof.
    Type: Grant
    Filed: September 11, 2018
    Date of Patent: February 21, 2023
    Assignee: F-star Therapeutics, Inc.
    Inventors: Radhakrishnan P. Iyer, Geeta Meher, Anjaneyulu Sheri, Shenghua Zhou, Sreerupa Challa, Rayomand H. Gimi, Seetharamaiyer Padmanabhan, Dillon Cleary
  • COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE
    Publication number: 20220168309
    Abstract: Disclosed are compounds and compositions for inhibiting the expression of a pattern recognition receptor (e.g., STING), and methods of use thereof.
    Type: Application
    Filed: March 5, 2020
    Publication date: June 2, 2022
    Inventors: RADHAKRISHNAN P. IYER, SEETHARAMAIYER PADMANABHAN, SUBRAMANIAN BASKARAN, ANJANEYULU SHERI, DILLON CLEARY, RON MASTROLIA, SHENGHUA ZHOU, SREERUPA CHALLA, RAYOMAND H. GIMI, VISHAL NAIR, LEENA PRABA SUPPIAH
  • COMPOUNDS,COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE
    Publication number: 20220054523
    Abstract: Disclosed are compounds and compositions for the activation or induction of expression of a pattern recognition receptor (e.g., STING, RIG-I, MDA5), and methods of use thereof.
    Type: Application
    Filed: June 4, 2021
    Publication date: February 24, 2022
    Inventors: Radhakrishnan P. Iyer, Anjaneyulu Sheri, Seetharamaiyer Padmanabhan, Geeta Meher, Shenghua Zhou, Sreerupa Challa, Rayomand H. Gimi, Dillon Cleary
  • COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE
    Publication number: 20210309692
    Abstract: Disclosed are compounds and compositions for the activation or induction of expression of a pattern recognition receptor (e.g., STING, RIG-I, MDA5), and methods of use thereof.
    Type: Application
    Filed: July 8, 2019
    Publication date: October 7, 2021
    Inventors: Radhakrishnan P. Iyer, Geeta Meher, Sreerupa Challa, Shenghua Zhou
  • COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE
    Publication number: 20210205347
    Abstract: Disclosed are compounds and compositions for the activation or induction of expression of a pattern recognition receptor (e.g., STING, RIG-I, MDA5), and methods of use thereof.
    Type: Application
    Filed: August 30, 2018
    Publication date: July 8, 2021
    Inventors: Radhakrishnan P. Iyer, Anjaneyulu Sheri, Geeta Meher, Sreerupa Challa, Shenghua Zhou
  • Compounds,Compositions, and methods for the treatment of disease
    Patent number: 11033569
    Abstract: Disclosed are compounds and compositions for the activation or induction of expression of a pattern recognition receptor (e.g., STING, RIG-I, MDA5), and methods of use thereof.
    Type: Grant
    Filed: July 6, 2017
    Date of Patent: June 15, 2021
    Assignee: Sperovie Biosciences, Inc.
    Inventors: Radhakrishnan P. Iyer, Anjaneyulu Sheri, Seetharamaiyer Padmanabhan, Geeta Meher, Shenghua Zhou, Sreerupa Challa, Rayomand H. Gimi, Dillon Cleary
  • COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE
    Publication number: 20200270299
    Abstract: Disclosed are compounds and compositions for the activation or induction of expression of a pattern recognition receptor (e.g., STING, RIG-I, MDA5), and methods of use thereof.
    Type: Application
    Filed: September 11, 2018
    Publication date: August 27, 2020
    Inventors: Radhakrishnan P. Iyer, Geeta Meher, Anjaneyulu Sheri, Shenghua Zhou, Sreerupa Challa, Rayomand H. Gimi, Seetharamaiyer Padmanabhan, Dillon Cleary
  • COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE
    Publication number: 20200268899
    Abstract: Disclosed are compounds and compositions for the activation or induction of expression of a pattern recognition receptor (e.g., STING, RIG-I, MDA5), and methods of use thereof.
    Type: Application
    Filed: September 11, 2018
    Publication date: August 27, 2020
    Inventor: Radhakrishnan P. Iyer
  • NUCLEOTIDE AND OLIGONUCLEOTIDE PRODRUGS
    Publication number: 20200087338
    Abstract: The present invention discloses compounds of formula (I): which exhibit antiviral properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of anti-HBV treatment. The invention also relates to methods of treating a HBV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
    Type: Application
    Filed: May 23, 2019
    Publication date: March 19, 2020
    Inventors: Radhakrishnan P. Iyer, Seetharamaiyer Padmanabhan
  • COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE
    Publication number: 20190292215
    Abstract: Disclosed are compounds and compositions for the induction of expression of a pattern recognition receptor (e.g., STING) and methods of use thereof.
    Type: Application
    Filed: July 14, 2017
    Publication date: September 26, 2019
    Inventors: Radhakrishnan P. Iyer, Seetharamaiyer Padmanabhan, Dillon Cleary, Geeta Meher, Rayomand H. Gimi, Anjaneyulu Sheri, Shenghua Zhou, Sreerupa Challa
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF HBV INFECTION
    Publication number: 20190290673
    Abstract: This invention relates to methods useful in the treatment of a hepatitis infection.
    Type: Application
    Filed: October 24, 2017
    Publication date: September 26, 2019
    Inventors: Radhakrishnan P. Iyer, Rayomand H. Gimi
  • COMPOUNDS,COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE
    Publication number: 20190262372
    Abstract: Disclosed are compounds and compositions for the activation or induction of expression of a pattern recognition receptor (e.g., STING, RIG-I, MDA5), and methods of use thereof.
    Type: Application
    Filed: July 6, 2017
    Publication date: August 29, 2019
    Inventors: Radhakrishnan P. Iyer, Anjaneyulu Sheri, Seetharamaiyer Padmanabhan, Geeta Meher, Shenghua Zhou, Sreerupa Challa, Rayomand H. Gimi, Dillon Cleary
  • Short oligonucleotides as vaccine adjuvants and therapeutic agents
    Patent number: 10391166
    Abstract: The invention provides a method of treating a microbial infection in a subject and a method of improving an immune system response in a subject against a disease, condition, infection, or virus thereof, by administering an effective amount of a nucleoside, short oligonucleotide compound or an analog thereof, or a pharmaceutically acceptable salt, racemate, enantiomer, diastereomer, geometric isomer, or tautomer thereof. In addition, the invention provides methods for treating or preventing a viral infection, bacterial infection, parasitic infection, or fungal infection in a subject (such as, a human). The compounds of the invention include, for example, di-, and trinucleotide compounds as provided herein. The compounds of the invention are useful for different therapeutic applications including, such as, prophylactics and therapeutics. The invention also provides design and synthesis of a compound that is useful for various therapeutic applications as mentioned herein.
    Type: Grant
    Filed: February 18, 2014
    Date of Patent: August 27, 2019
    Assignee: SPRING BREAK PHARMACEUTICALS, INC.
    Inventor: Radhakrishnan P. Iyer
  • Compositions and methods for treating viral infections
    Patent number: 10376533
    Abstract: The present invention provides compositions methods for treating susceptible viral infections, especially hepatitis C viral (HCV) infections as well as co infections of HCV with other viruses such as HBV and/or HIV. In one embodiment, the present invention provides compositions having the formula (I) and their use in treating viral infections: or a pharmaceutically acceptable salt, ester, stereoisomer, tautomers, solvate, prodrug, or combination thereof.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: August 13, 2019
    Assignee: Spring Bank Pharmaceuticals, Inc.
    Inventors: Radhakrishnan P. Iyer, Seetharamaiyer Padmanabhan
  • Nucleotide and oligonucleotide prodrugs
    Patent number: 10344046
    Abstract: The present invention discloses compounds of formula (I): which exhibit antiviral properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of anti-HBV treatment. The invention also relates to methods of treating a HBV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
    Type: Grant
    Filed: March 15, 2018
    Date of Patent: July 9, 2019
    Assignee: Spring Bank Pharmaceuticals, Inc.
    Inventors: Radhakrishnan P. Iyer, Seetharamaiyer Padmanabhan