Patents by Inventor Radoje T. Drmanac

Radoje T. Drmanac has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND MATERIALS RELATING TO SEMAPHORIN-LIKE POLYNUCLEOTIDES
    Publication number: 20040220383
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted semaphorin-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from fetal liver-spleen (Hyseq clone identification numbers 5688868 (SEQ ID NO. 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted semaphorin-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: June 12, 2003
    Publication date: November 4, 2004
    Inventors: Bryan J. Boyle, George Yeung, Matthew C. Arterburn, Nancy K. Mize, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Novel nucleic acids and polypeptides
    Publication number: 20040219521
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: April 22, 2002
    Publication date: November 4, 2004
    Inventors: Y. Tom Tang, Zhiwei Wang, Gezhi Weng, Bryan J. Boyle, Radoje T. Drmanac
  • Methods and materials relating to alpha-2-macroglobulin-like polypeptides and polynucleotides
    Patent number: 6806254
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to novel human secreted alpha-2-macroglobulin-like polypeptides. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from fetal brain mRNA (Clontech) (SEQ ID NO: 1) and uterus mRNA (Clontech) (SEQ ID NO: 26). Other aspects of the invention include vectors containing processes for producing novel human secreted alpha-2-macroglobulin-like polypeptides, and antibodies specific for such polypeptides.
    Type: Grant
    Filed: January 8, 2001
    Date of Patent: October 19, 2004
    Assignee: Nuvelo, Inc.
    Inventors: Shubhada D. Godbole, Bryan J. Boyle, Nancy K. Mize, Cenhua Deng, Ryle W. Goodrich, Matthew C. Arterburn, Ping Zhou, Y. Tom Tang, Chenghua Liu, George Yeung, Radoje T. Drmanac
  • Cathepsin V-like polypeptides
    Patent number: 6783969
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Grant
    Filed: March 5, 2001
    Date of Patent: August 31, 2004
    Assignee: Nuvelo, Inc.
    Inventors: Y. Tom Tang, Ryle W. Goodrich, Vinod Asundi, Radoje T. Drmanac
  • Methods and materials relating to novel growth regulatory-like polypeptides and polynucleotides
    Publication number: 20040162419
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human growth regulatory-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA libraries from human thymus (Hyseq clone identification number 16372272). Other aspects of the invention include vectors containing processes for producing novel human growth regulatory-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: October 2, 2003
    Publication date: August 19, 2004
    Inventors: Bryan J. Boyle, Nancy K. Mize, Matthew C. Arterburn, John E. Ford, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Methods and materials relating to alpha-2-macroglobulin like polypeptides and polynucleotides
    Publication number: 20040152884
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to novel human secreted alpha-2-macroglobulin-like polypeptides. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from fetal brain mRNA (Clontech) (SEQ ID NO: 1) and uterus mRNA (Clontech) (SEQ ID NO: 26). Other aspects of the invention include vectors containing processes for producing novel human secreted alpha-2-macroglobulin-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: March 5, 2004
    Publication date: August 5, 2004
    Inventors: Shubhada D. Godbole, Bryan J. Boyle, Nancy K. Mize, Cenhua Deng, Ryle W. Goodrich, Matthew C. Arterburn, Ping Zhou, Y. Tom Tang, Chenghua Liu, George Yeung, Radoje T. Drmanac
  • Novel nucleic acids and polypeptides
    Publication number: 20040137434
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: April 3, 2002
    Publication date: July 15, 2004
    Inventors: Y. Tom Tang, Ping Zhou, Ryle Goodrich, Chenghua Liu, Vinod Asundi, Feiyan Ren, Jie Zhang, Qing A. Zhao, Aidong Xue, Yonghong Yang, Tom Wehrman, Radoje T. Drmanac
  • Methods and materials relating to soluble transforming growth factor alpha-like polypeptides and polynucleotides
    Publication number: 20040132022
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted TGF alpha-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human adult kidney (Hyseq clone identification number 16441036). Other aspects of the invention include vectors containing processes for producing novel human secreted TGF alpha-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: March 1, 2004
    Publication date: July 8, 2004
    Inventors: Bryan J. Boyle, Nancy K. Mize, Matthew C. Arterburn, Servando Palencia, Y Tom Tang, Chenghua Liu, Radoje T. Drmanac, Ivan Labat, Birgit Stache-Crain, Kody Nguyen, Veronica E. Garcia
  • Methods and materials relating to semaphorin-like polypeptides and polynucleotides
    Publication number: 20040121948
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted semaphorin-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from fetal liver-spleen (Hyseq clone identification numbers 5688868 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted semaphorin-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: October 3, 2003
    Publication date: June 24, 2004
    Inventors: Bryan J Boyle, Nancy K. Mize, Matthew C. Arterburn, George Yeung, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Methods and materials relating to neurotrimin-like polypeptides and polynucleotides
    Publication number: 20040116683
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted neurotrimin-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from human thalamus (Hyseq clone identification number 10468562). Other aspects of the invention include vectors containing processes for producing novel human secreted neurotrimin-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: September 29, 2003
    Publication date: June 17, 2004
    Inventors: Bryan J. Boyle, Nancy K. Mize, Matthew C. Arterburn, George Yeung, Y. Tom Tang, Ping Zhou, Chenghua Liu, Radoje T. Drmanac, Vinod Asundi, Menq-Yun Wang, Lichuan Chen, Yea-Huey Yang
  • Novel nucleic acids and polypeptides
    Publication number: 20040110940
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: June 10, 2002
    Publication date: June 10, 2004
    Inventors: Y. Tom Tang, Ping Zhou, Feiyan Ren, Radoje T. Drmanac
  • Methods and materials relating to hematopoietic cytokine-like polypeptides and polynucleotides
    Publication number: 20040106116
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted HC-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from thymus (Hyseq clone identification numbers 15097076 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted HC-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: July 15, 2003
    Publication date: June 3, 2004
    Inventors: Bryan J. Boyle, Nancy K. Mize, Matthew C. Arterburn, Servando Palencia, Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Nucleic acids and polypeptides
    Patent number: 6743619
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Grant
    Filed: January 30, 2001
    Date of Patent: June 1, 2004
    Assignee: Nuvelo
    Inventors: Y. Tom Tang, Ping Zhou, Ryle Goodrich, Chenghua Liu, Vinod Asundi, Feiyan Ren, Jie Zhang, Qing A. Zhao, Yonghong Yang, Aidong J. Xue, Tom Wehrman, Jian-Rui Wang, Dunrui Wang, Radoje T. Drmanac
  • Methods and materials relating to leucine-rich repeat protein-like (lrr protein-like) polypeptides and polynucleotides
    Publication number: 20040072173
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted LRR protein-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA library from thymus (Hyseq clone identification numbers 16395938 (SEQ ID NO: 1)). Other aspects of the invention include vectors containing processes for producing novel human secreted LRR protein-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: September 26, 2003
    Publication date: April 15, 2004
    Inventors: Bryan J. Boyle, Nancy K. Mize, Mattew C. Arterburn, George Yeung, Y.Tom Tang, Chenghua Liu, Radoje T. Drmanac, Menq-Yun Wang, Linchuan Chen, Yea-Huey Yang
  • Method and materials relating to g protein-coupled receptor-like polypeptides and polynucleotides
    Publication number: 20040068097
    Abstract: The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human secreted GPCR-like polypeptide. These polynucleotides comprise nucleic acid sequences isolated from cDNA libraries from human leukocyte mRNA (GIBCO Laboratories) (SEQ ID NO: 1), from human adult liver mRNA (GIBCO) (SEQ ID NO: 10); from human adult kidney mRNA (GIBCO) (SEQ ID NO: 17); from human adult brain mRNA (GIBCO) (SEQ ID NO: 26) and from human adult kidney mRNA (Invitrogen) (SEQ ID NO: 33). Other aspects of the invention include vectors containing processes for producing novel human secreted GPCR-like polypeptides, and antibodies specific for such polypeptides.
    Type: Application
    Filed: September 26, 2003
    Publication date: April 8, 2004
    Inventors: Victoria Yamazaki, Y. Tom Tang, Chenghua Liu, Ping Zhou, Dunrui Wang, Jie Zhang, Feiyan Ren, Vinod Asundi, Radoje T. Drmanac
  • Egf motif protein, egfl6 materials and methods
    Publication number: 20040059098
    Abstract: The present invention provides novel polynucleotides and proteins encoded by such polynucleotides, along with therapeutic, diagnostic and research utilities for these polynucleotides and proteins. In particular, the polypeptides of the invention is useful for detecting cancers.
    Type: Application
    Filed: October 2, 2003
    Publication date: March 25, 2004
    Inventors: Y. Tom Tang, Chenghua Liu, Vinod Asundi, John E. Ford, Victoria Yamazaki, George Yeung, Jie Zhang, Ping Zhou, Radoje T. Drmanac, Hua Zhou
  • Novel nucleic acids and polypeptides
    Publication number: 20040053245
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: June 24, 2003
    Publication date: March 18, 2004
    Inventors: Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Novel arginine-rich protein-like nucleic acids and polypeptides
    Publication number: 20040053250
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: November 21, 2002
    Publication date: March 18, 2004
    Inventors: Y. Tom Tang, Aidong Xue, Radoje T. Drmanac
  • Novel nucleic acids and polypeptides
    Publication number: 20040053248
    Abstract: The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
    Type: Application
    Filed: June 24, 2003
    Publication date: March 18, 2004
    Inventors: Y. Tom Tang, Chenghua Liu, Radoje T. Drmanac
  • Methods of immunotherapy and diagnosis
    Publication number: 20040048817
    Abstract: Certain cells, including types of cancer cells such as T-cell lymphoma, T-cell leukemia, multiple myeloma, and chronic myeloid leukemia, B cell lymphoma of mature B cell lineage, non-Hodgkin's lymphoma of mature B-cell lineage, and Burkitt's lymphoma of mature B cell lineage, are capable of expressing SEQ ID NO: 2 or 4-ecoding RNA. Immunotargeting using SEQ ID NO: 2 or 4 polypeptides, nucleic acids encoding for SEQ ID NO: 2 or 4 polypeptides and anti-SEQ ID NO: 2 or 4 antibodies provides a method of killing or inhibiting that growth of cancer cells that express the SEQ ID NO: 2 or 4 protein. Methods of immunotherapy and diagnosis of disorders associated with SEQ ID NO: 2 or 4 protein-expressing cells, such as T-cell lymphoma, T-cell leukemia, multiple myeloma, and chronic myeloid leukemia, B cell lymphoma of mature B cell lineage, non-Hodgkin's lymphoma of mature B-cell lineage, and Burkitt's lymphoma of mature B cell lineage, are described.
    Type: Application
    Filed: November 26, 2002
    Publication date: March 11, 2004
    Inventors: Peter C.R. Emtage, Y. Tom Tang, Zhiwei Wang, Radoje T. Drmanac